The invention discloses Shenkangding Jiaonang for treating chronic nephrosis. The Shenkangding Jiaonang is prepared from the following raw materials in part by weight: 27 to 33 parts of sculellaria barbata, 27 to 33 parts of winged euonymus twig, 27 to 33 parts of oldenlandia diffusa, 8 to 12 parts of paniculate swallowwort root, 13 to 17 parts of alisma plantagoaquatica, 13 to 17 parts of fried atractylodes lancea, 27 to 33 parts of lightyellow sophora root, 8 to 12 parts of honeysuckle, 8 to 12 parts of hiraute shiny bugleweed herb, 17 to 23 parts of root of red-rooted salvia, 13 to 17 parts of Chinese pyrola herb, 22 to 28 parts of hairyvein agrimonia herb and bud, 11 to 14 parts of root of rehmannia, 13 to 17 parts of fried bighead atractylodes rhizome, 8 to 12 parts of eucommia bark, and 8 to 12 parts of safflower. The invention has the advantages of eliminating the pathogenic factor and eliminating body resistance by strengthening the spleen, tonifying kidney and qi, nourishing yin, activating blood circulation, promoting dieresis, detoxifying and removing stasis. Meanwhile, Shenkangding Jiaonang can reduce proteinuria and hematuresis and can improve kidney functions. The Shenkangding Jiaonang also has the characteristics of good treatment effect, readily available material, simple preparation process, low preparation cost, low price that can be afforded by ordinary people, safety, no toxic or side effects, and convenient administration.