Chinese medicinal capsules for treating prostatitis and prostatic hyperplasia and preparation method for Chinese medicinal capsules

A technology for prostatic hyperplasia and traditional Chinese medicine capsules is applied in the field of traditional Chinese medicine, which can solve the problems of low transfer rate of active ingredients, and achieve the effects of improving bioavailability, stable quality and preventing moisture.

Inactive Publication Date: 2012-07-04
史志辉 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The present invention aims at the defect that the current similar products have a low transfer rate of active ingredients in the extraction method of the six Chinese medicinal materials of Radix Paeoniae Rubra, Danshen, Peach Kernel, Wuyao, Wangbuliuxing, and Angelica dahurica, an

Method used

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  • Chinese medicinal capsules for treating prostatitis and prostatic hyperplasia and preparation method for Chinese medicinal capsules
  • Chinese medicinal capsules for treating prostatitis and prostatic hyperplasia and preparation method for Chinese medicinal capsules
  • Chinese medicinal capsules for treating prostatitis and prostatic hyperplasia and preparation method for Chinese medicinal capsules

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Effect test

Embodiment 1

[0030] According to the preparation method of the present invention, the following Chinese medicine raw materials are processed and prepared in parts by weight: 200 parts of Radix Paeoniae Rubra, 100 parts of Salvia Miltiorrhiza, 140 parts of Peach Kernel, 120 parts of Eupatorium, 120 parts of Wuyao, and 80 parts of Wang Buliuxing , 80 parts of Angelica dahurica. Add red peony root, salvia miltiorrhiza, zeilan, wangbuliuxing and angelica dahurica, add water and heat to 80°C, then add peach kernels, continue heating, decoct three times, the first time for 2 hours, the mass ratio of the raw materials to distilled water is 1:12 1.5 hours for the second time, the mass ratio of the raw material and distilled water was 1: 10; 1 hour for the third time, the mass ratio of the raw material and distilled water was 1: 10, the combined decoction was filtered, and the filtrate was concentrated into a relative The thick paste with a density of 1.35 (80° C.) was dried under reduced pressure ...

Embodiment 2

[0067] Embodiment 2: Chinese medicine capsules made according to the preparation method of the present invention

[0068] Weigh 200kg of Cortex Phellodendri, 200kg of Radix Paeoniae Rubra, 100kg of Salvia Miltiorrhiza, 140kg of Peach Kernel, 120kg of Eupatorium, 120kg of Wuyao, 80kg of Wangbuliuxing, and 80kg of Angelica dahurica; Chishao, Danshen, Zelan, Wuyao, Wangbuliuxing and Baizhi add 12 times the amount of water and heat to 80°C, then add peach kernels, make up the water to 12 times the weight of the total medicinal materials, continue heating, and decoct three times , for the first time for 2 hours; for the second time, add 10 times the amount of water to decoct for 1.5 hours; for the third time, add 10 times the amount of water to decoct for 1 hour, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.35 (80°C ) thick paste, dried under reduced pressure, crushed into fine powder, added Cortex Phellodendri fine powder, mixed evenly, pa...

Embodiment 3

[0073] Embodiment 3: the pharmaceutical test of the capsule prepared by the preparation method of the present invention

[0074] According to the preparation method provided by the embodiment of the present invention 2, the traditional Chinese medicine capsules made by the acute toxicity maximum tolerance test in the animal body, the daily maximum tolerated dose of intragastric administration to mice is 582 times of the adult clinical daily dose. The toxic reaction of the traditional Chinese medicine capsules made by the preparation method provided by the invention is not observed under this dosage.

[0075] The traditional Chinese medicine capsules prepared according to the preparation method provided in Example 2 of the present invention were subjected to a 6-month long-term toxicity test in animals, and administered to rats by intragastric administration every day, and the doses were respectively equivalent to 100 times the clinical daily dosage of adults. , 50 times, 25 time...

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Abstract

The invention relates to the field of Chinese medicines and discloses Chinese medicinal capsules for treating prostatitis and prostatic hyperplasia and a preparation method for the Chinese medicinal capsules. By the preparation method, the transfer rates of eight medicinal active ingredients, namely phellodendrine, tanshinone IIA, salvianolic acid B, paeoniflorin, amarogentin, linderane, vaccarin and imperatorin in phellodendron, red paeony root, root of red-rooted salvia, peach kernel, root of combined spicebush, cowherb seed and angelica dahurica are all improved to over 95 percent, and are remarkably higher than the transfer rate obtained by the conventional method in China, so that the medicinal effect is improved and the cost is reduced.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine capsule for treating prostatitis and benign prostatic hyperplasia and a preparation method thereof. Background technique [0002] From the analysis of clinical manifestations, prostatitis and benign prostatic hyperplasia should belong to the category of "damp-heat syndrome". According to the point of view of TCM syndrome differentiation and treatment, this disease is mostly caused by the accumulation of damp-heat in the lower energizer. The treatment should focus on clearing away heat and promoting dampness. Those who recover should invigorate the spleen and kidney, supplemented by clearing away heat and promoting dampness. [0003] Cortex Phellodendri clears away heat and dampness, purging fire and removing steam; Radix Paeoniae Rubra clears heat and cools blood, dissipates blood stasis and relieves pain; Water reduces swelling; Wuyao s...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K9/48A61P13/08
Inventor 史志辉
Owner 史志辉
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