The invention discloses a preparation method of a
traditional Chinese medicine composition for treating advanced non-
small cell lung cancers. The method comprises the following steps of: 1. taking root of glaucescent
fissistigma, barbated skullcup
herb, radix astragali, sanqi and platycodon root; 2. removing impurities from sanqi and washing,
drying,
grinding, sieving and sterilizing sanqi, removing impurities from barbated skullcup
herb and washing and
cutting barbated skullcup
herb into segments, removing impurities from glaucescent
fissistigma, radix astragali and platycodon root and washing, moistening and
slicing glaucescent
fissistigma, radix astragali and platycodon root; 3. mixing barbated skullcup herb, glaucescent fissistigma, radix astragali and platycodon root and then adding water to soak the medicines, decocting the medicines and filtering the decoction; 4. adding water to the
medicine dregs, decocting the
medicine dregs, filtering the decoction, mixing the filtrate and concentrating the filtrate into thick paste under reduced pressure; 5. adding sanqi to the thick paste, mixing the medicines uniformly and then
drying the mixture under reduced pressure,
grinding the dried mixture and sieving the
powder to obtain dry paste
powder; and 6. capsulizing the dry paste
powder to obtain a
capsule, or adding
dextrin and
magnesium stearate to the dry paste powder, mixing the materials uniformly, granulating the mixture,
drying the granules under reduced pressure, tabletting the dried granules and sugarcoating, thus obtaining a tablet. The preparation method has the advantages that the anticancer active ingredients in the
traditional Chinese medicine are fully extracted and the transfer rates of the anticancer active ingredients are above 90%.