119results about How to "Avoid oxidative degradation" patented technology

The invention discloses a copolymer with temperature resistance and water solubility and the preparation method and application thereof, which is characterized in that: 20 portions of acrylic amide, 0.1 to 10 portions of anion monomer or/and cation monomer, 0.05 to 3 portions of fluorine-containing styrene or/and perfluoroalkyl styrene hydrophobic monomer, 0.5 to 60 portions of surface active agent and 50 to 700 portions of deionized water are put into a three-necked reaction bulb; after the solution pH is regulated to be equal to 2.5 to 9 and N2 is connected for 30 minutes, 0.001 to 0.2 portion of an evocating agent of persulfate is added under temperature of 20 to 70 DEG C, reacting for 6 to 36 hours, and PATF is prepared. Then water is used for diluting so as to prepare PATF concentrated solution, thus obtaining a copolymer that has medium molecular weight and water solubility, is high-temperature resistant, has an ability of molecular association and can be used in high temperature and high salinity reservoir. The copolymer is prepared into aqueous solution with a mass concentration of 0.3 to 3g/L and a surface-active-agent concentration of 0.01 to 4mmol/L, which is put in a blending container with a dasher and is stirred even at room temperature to prepare a polymer oil-displacing agent which is high-temperature resistant, high tackifying and anti-sharing and has excellent aging resistance under high salinity and the temperature of 110 DEG C. The prepared oil-displacing polymer has excellent solution properties owing to the supermolecular structure formed by the association between molecules of fluorine-containing cinnamene or/and alkylbenzene hydrophobic groups, thus having favorable application prospects in high temperature and high salinity reservoir exploitation.

The invention relates to the field of high polymer materials and particularly relates to a highly-abrasion-resistant anti-scratching modified PC (polycarbonate) material and a preparation method thereof. The high-abrasion-resistant anti-scratching modified PC material comprises the following raw materials in parts by weight: 65-90 parts of PC, 10-35 parts of abrasion-resistant anti-scratching auxiliary agent, 0.5-1.5 parts of coupling agent, 1-10 parts of toughening agent, 0.1-1 part of antioxidant and 0.1-1 part of lubricating agent. According to the invention, PC is used as a substrate material, and composite systems such as the abrasion-resistant anti-scratching auxiliary agent, the lubricating agent, other auxiliary agents and the like are added, so that the abrasion-resistant anti-scratching property of the material is improved; the abrasion-resistant anti-scratching modified PC material is prepared by adopting high-temperature smelting, mixing and extruding modes in a twin-screw extruder, thus the hardness and abrasion-resistant anti-scratching effect of PC are improved; and modified PC has the advantages of high rigidity, high toughness, high flowability, high heat resistance, bright surface and the like.

A modified water-immiscible solvent useful in the extraction of acetic acid from aqueous streams is a substantially pure mixture of isomers of highly branched di-alkyl amines. This solvent is substantially devoid of mono-alkyl amines and alcohols. Solvent mixtures formed of such a modified solvent with a desired cosolvent, preferably a low boiling hydrocarbon which forms an azeotrope with water are useful in the extraction of acetic acid from aqueous gaseous streams. An anaerobic microbial fermentation process for the production of acetic acid employs such solvents, under conditions which limit amide formation by the solvent and thus increase the efficiency of acetic acid recovery. Methods for the direct extraction of acetic acid and the extractive fermentation of acetic acid also employ the modified solvents and increase efficiency of acetic acid production. Such increases in efficiency are also obtained where the energy source for the microbial fermentation contains carbon dioxide and the method includes a carbon dioxide stripping step prior to extraction of acetic acid in solvent.

The invention relates to a method for thermally modifying wood by oil palm oil. The method comprises the following steps of: stacking the wood stably, and then placing the wood stack in a treating tank; heating up the oil palm oil and then filling to the treating tank, completely covering the wood by the oil palm oil, heating up the wood, and keeping the temperature for 0.5-3 hours for thermally modifying the wood when the temperature of the wood reaches 200-215 DGE C; and stopping heat supply, then discharging the oil palm oil immediately, filling atomized water into the treating tank to gradually cool the wood, and then naturally cooling the wood to the room temperature (30 DEG C) so as to complete the treatment. The method in the invention is simple in process; the wood is isolated from the air by the oil palm oil; the wood is effectively prevented from oxidation and degradation; the thermal treatment features in fast heating speed, short treating period and low cost; the treated wood features in increased size stability, small bending resistance intensity loss, high corrosion resistance, high intensity, good durability and the like; and the wood is convenient for industrial application, and can be widely used for the indoor and outdoor furniture, landscapes, finishing materials and the like.

The present invention discloses one kind of heat resistant nylon material containing thermal liquid crystal polymer. The heat resistant nylon material consists of nylon-6 slice 60-70 wt%, thermal liquid crystal polymer 25-35 wt%, cross-linking agent 4.5 wt% and antioxidant 0.5 wt%. Its preparation process includes the steps of: mixing all the components via stirring, extruding at 250 deg.c or 260 deg.c, drawing, pelletizing and injection molding. The heat resistant nylon material has Vicat softening point up to 230 deg.c and high melt flow rate, and may be used in making different kinds of heat resistant nylon parts.

The invention relates to the technical field of pharmaceutical preparations, in particular to a pharmaceutical composition containing mecobalamin and a preparation method thereof. The pharmaceutical composition containing mecobalamin is composed of, by mass percentage, 0.01-1% of methylcobalamin, 1%-10% of a stabilizer, 40-95% of a diluent, 0-20% of a disintegrant, and 0.1-10% of a lubricant. The preparation method consists of: premixing mecobalamine and part of the diluents, then mixing the pre-mixture with the stabilizer, the diluent and the disintegrant to obtain mixed powder, mixing the mixed powder with the lubricant for a certain period of time to obtain mixed raw material powder, and subjecting the mixed raw material powder to direct tabletting and coating. The method provided by the invention adopts a dry granulation process, involves fewer steps, avoids the influence of moisture and heat to the main drug, further improves the quality of mecobalamin tablets, lowers the cost, and is beneficial to industrial production.

The present invention is directed to compositions and devices for transdermally administering vitamin B₁₂ to a subject. In one aspect, a vitamin B₁₂ containing composition suitable for transdermal administration is provided in the form of a shelf stable transdermal delivery patch. Such patches contain vitamin B₁₂ combined with selected penetration enhancers and vitamin B₁₂ stabilizers.

The invention discloses a preparation method of everolimus solid dispersion. The preparation method particularly comprises the following steps that 1, everolimus, hydroxypropyl methyl cellulose and organic solvent are stirred and mixed to be uniform; 2, the organic solvent in the materials which are stirred to be uniform in the step 1 is removed through a microwave vacuum drying method, and then the everolimus solid dispersion is obtained, wherein the vacuum degree of microwave vacuum drying is lower than or equal to 0.080 MPa, and the drying temperature is lower than or equal to 55 DEG C. According to the method, the organic solvent in the preparation process of the everolimus solid dispersion is removed by adopting the microwave vacuum drying method which is conventionally applied to agricultural product and food processing, oxidative degradation of everolimus can be effectively avoided, the drying efficiency can be greatly improved, the dried materials are loose in surface, and the next processing step is easy to operate.

The invention discloses a preparation method of antibacterial conductive adhesive hydrogel. The preparation method is characterized by comprising the following steps: forming an aqueous solution with a certain concentration from chitosan quaternary ammonium salt, adding a proper amount of tannic acid, stirring to form a tannic acid/chitosan quaternary ammonium salt precursor solution, then adding an acrylic monomer, uniformly stirring, adding a cross-linking agent and an initiator, and preparing and molding through a one-pot method. The hydrogel obtained by the invention has good biocompatibility, antibacterial property, adhesiveness and oxidation resistance, also has good conductivity and strain sensitivity, and can be used in the biomedical fields of wound repair, electronic skin, human-computer interaction, health monitoring, wearable electronic equipment and the like.

The invention discloses a carbon fiber reinforced resin composite material, use thereof and a preparation method of a rubber frame of an electronic equipment enclosure and/or a module, and relates to the technical field of carbon fiber reinforced resin composite materials. A product injection-molded by the carbon fiber reinforced resin composite material can not only meet the requirements of high rigidity and high dimensional stability, but also obtain high-light spraying-free effects. The carbon fiber reinforced resin composite material is prepared from the following components: 15-25wt% of carbon fibers, 50-70wt% of PC+ABS alloy, 10-20wt% of a smoothing agent, 2-4wt% of a flexibilizer and 0.3-0.5wt% of an antioxidant, wherein the melt index of the PC+ABS alloy is greater than and equal to 40. The carbon fiber reinforced resin composite material disclosed by the invention is applicable to the injection molding of thin-wall products.

The invention discloses a polycarbonate nylon polymer alloy of solvent-resistant xylene and the preparation method. Based on weight proportion, the polycarbonate nylon polymer alloy is composed of 74.5 to 81.7 portions of polycarbonate, 15 to 20 portions of polydecamrthylene sebacamide, 3 to 5 portions of compatibilizer and 0.3 to 0.5 portion of antioxidant. The preparation method is that the components are dried and mixed evenly, and then extruded, towed and granulated at 255 to 275 DEG C to prepare the polycarbonate nylon polymer alloy of solvent-resistant xylene. As polydecamrthylene sebacamide forms network micro-fiber structures in the polycarbonate resin matrix, so the polycarbonate is endowed with excellent solvent-resistant performance so as to improve the solvent-resistant cracking property of the polycarbonate and enable the alloy to have good processing flowability, as well as ensure good mechanical properties at the same time, therefore, the alloy can be used as plastic parts for xylene-resistant solvents.

The invention discloses a method for simultaneously extracting paclitaxel and 10-DABIII (10-Deacetyl Baccatin III) from taxus chinensis. The method comprises the following steps: crushing taxus chinensis leaves into powder; soaking with an extraction solvent; putting a mixed liquid into a crushing extraction device; extracting for 1-3 times; performing crushing extraction at a low temperature andhigh pressure; after paclitaxel and 10-DABIII are rapidly dissolved into the extraction solvent, performing centrifugal separation on supernate and precipitate, thereby obtaining the supernate, that is, extracts of paclitaxel and 10-DABIII. Due to the low temperature and the high pressure, paclitaxel and 10-DABIII can be simultaneously extracted in one process, and in addition, the extraction rateof paclitaxel and 10-DABIII is as high as 96%. The method disclosed by the invention has the advantages of being good in stability, simple to operate, short in preparation time, high in extraction efficiency, safe and non-toxic, and the like, and meanwhile paclitaxel and 10-DABIII can be effectively prevented from oxydative degradation.

The invention discloses a formula and a preparation method of a non-allergenic and painless novel propofol fatty microemulsion freeze-drying preparation. The novel preparation comprises artificially synthesized phospholipid and artificially synthesized fatty acid glyceride, the presence of such allergic sources as a trace of protein in lecithin and soybean oil as natural sources is avoided, the uses of a metal complex EDTA, an antioxidant sulfite and thiosulfate is avoided, the allergic reaction caused by a metal complexing agent and sulfide is eliminated; a water phase free propofol is removed through various means in the formulation and preparation process, so that the injection pain is alleviated or eliminated and thus the safety of the preparation and the compliance of patients are improved.

The invention relates to a method for extracting molybdenum by sub-step dynamic acid adjustment. The method comprises the following steps: (S101) ammonium sulfate and vanadium and molybdenum-contained waste catalyst solution are mixed, and are filtered after full precipitation to obtain residues-ammonium metavanadate and filtrates; (S102) the pH value of the filtrates is adjusted to 6.5-6.8 by acid solution; and (S103) a transformed extracting agent is adopted to extract the filtrates treated in the step (S102) to obtain a molybdenum-loaded organic phase and a raffinate water phase, wherein the extraction is single-grade three-section extraction; and in the extracting process, the acid solution is respectively fed by three stages. The method for extracting molybdenum by sub-step dynamic acid adjustment realizes adjustment of acid during extracting through a sub-step acid feeding method to reduce the concentration of molybdenum in the water phase, so that the molybdenum is not precipitated in the extracting process, the molybdenum is extracted in an optimal pH value range by tertiary amine-kerosene solution, the high-efficiency molybdenum extraction is realized, the operation conditions are improved, the consumption of sulfuric acid is saved, and the molybdenum recovery rate is increased.

This invention provides a safe and high efficiency method for extracting bee pollen grease by using supercritical fluid. The method comprises: (1) adding bee pollen to an extractor, adding propane, butane or their mixture, and extracting under stirring; (2) removing the solvent from bee pollen and mixed oil, respectively; (3) recovering and recycling the solvents, and obtaining bee pollen and bee pollen grease. The method has such advantages as high efficiency, high extraction rate, short extraction time, low cost, low solvent consumption, and high product quality. The bee pollen grease can be used to treat cardiovascular diseases, inflammation and cancer, and can promote brain development.

The invention discloses application of juglone in the treatment of human liver cancer, wherein the juglone can inhibit the proliferation and invasion of human liver cancer cells, can inhibit the growth of tumor cells in the treatment of human liver cancer, and can be used for preparing anti-tumor drugs; meanwhile, the invention also discloses an extraction method of the juglone, firstly, walnut green tangerine peel is dried and crushed, then the walnut green tangerine peel is leached with ethanol solution under the aid of double-frequency ultrasonic waves, and finally, the walnut green tangerine peel is purified by D101 resin to obtain a juglone pure product. The juglone has the advantages of inhibiting proliferation and invasion of HepG2 cells, inhibiting the growth of tumor cells in thetreatment of human liver cancer, and directly killing tumor cells and inhibiting the invasion. The method of extracting the juglone from walnut green tangerine peel is simple and easy. The yield and the biological efficacy of the juglone can be well preserved, and oxidative degradation of the juglone and the derivatives thereof can be prevented.

The invention discloses rare earth composite coated titanium dioxide as well as a preparation method and application thereof, and belongs to the technical field of titanium dioxide production. The method comprises the following steps: a titanium dioxide crude product is crushed by a rolling mill and then enters a pulping tank, desalted water and a dispersing agent are added at the same time, uniform stirring is performed to prepare titanium dioxide crude product slurry, and the obtained slurry is subjected to wet grinding by a ball mill; grinding the slurry by a sand mill; transferring the ground slurry into a surface treatment tank for inorganic surface treatment; transferring the obtained slurry into a plate-and-frame filter press for filter pressing, and washing with desalted water to obtain a filter cake; and drying the filter cake to obtain a titanium dioxide material, and carrying out organic coating on the titanium dioxide material through a jet milling process to obtain a titanium dioxide finished product. Compared with a conventional product, the titanium dioxide prepared by the preparation method disclosed by the invention is better in whiteness and stronger in light resistance, and has better application performance in an application system.

The invention discloses a method for dissolving ambroxol hydrochloride raw materials. The method comprises the following steps: A, taking 25L of water for injection, adding auxiliary materials such as 3.0kg of citric acid, 2.4kg of disodium hydrogen phosphate and 1.5kg of sodium hydrogen sulfite, and adding 0.9kg of ambroxol hydrochloride after dissolving, thereby obtaining the concentrated liquor of ambroxol hydrochloride for later use; B, adding the concentrated liquor of ambroxol hydrochloride into a dilution tank, adding water for injection to reach 3000L, and stirring for 10 minutes, thereby obtaining an initial solution of ambroxol hydrochloride; and C, performing circulating filtration by virtue of a titanium stick filter, and preparing the ambroxol hydrochloride solution at the temperature of 50-60 DEG C by virtue of a first pleated filter cartridge filter and a second pleated filter cartridge filter. According to the method disclosed by the invention, ambroxol hydrochloride can be completely dissolved in water, the uniformity is high, the oxidative degradation problem of ambroxol hydrochloride can be effectively solved, and the ambroxol hydrochloride solution with good dissolving property and difficulty in denaturation is prepared.

The invention discloses a desulfurization wastewater treatment process, which comprises a desulfurization wastewater pretreatment step, a desulfurization wastewater membrane concentration treatment step and a desulfurization wastewater salting-out pretreatment step, wherein the desulfurization wastewater pretreatment step comprises a two-stage electrochemical treatment step and a two-stage softening treatment step, the membrane concentration treatment section is designed into two-stage membrane treatment and comprises a rolled RO device and a mesh pipe type STRO device, and an MVR evaporator and a spray evaporator are combined in the salting-out the treatment section. According to the present invention, any organic agents are not added in the whole process.