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11results about How to "Avoid oxidative degradation" patented technology

A method for multi-product cascade separation of haematococcus based on coupling of low eutectic solvent sequential extraction and enzyme membrane reactor

ActiveCN121371677BEffective dissociationImprove extraction efficiencyDepsipeptidesNatural dyesEnzyme membraneHaematococcus
The application belongs to the technical field of natural substance separation and extraction, and particularly relates to a kind of Haematococcus pluvialis multi-product cascade separation method based on eutectic solvent sequential extraction and enzyme membrane reactor coupling, comprising the following steps: (1) cell wall weakening pretreatment step; (2) water-soluble component extraction step; (3) pigment component extraction step; (4) astaxanthin extraction step; (5) enzyme conversion step. Through the synergistic effect of eutectic solvent sequential extraction and enzyme membrane reactor, efficient, green and continuous cascade separation of water-soluble components, pigments, astaxanthin and xylo-oligosaccharides in Haematococcus pluvialis is realized, and product purity and resource utilization are improved.
Owner:ERFA BIOTECHNOLOGY (JIAXING) CO LTD

A trenchless composite inner liner pipe resistant to chemical corrosion

ActiveCN224622380UEffective against erosionresist erosion
This utility model discloses a trenchless composite liner pipe with chemical corrosion resistance, comprising a chemical corrosion resistant inner layer, an outer surface of which is provided with a reinforcing structural layer, an outer surface of which is provided with an elastic buffer layer, an outer surface of which is provided with an adhesive transition layer, and a connector fixedly connected to the side surface of the chemical corrosion resistant inner layer. A sealing ring is provided on the inner surface of the connector. Through the dual protection of hindered phenolic antioxidants and benzotriazole ultraviolet absorbers in the chemical corrosion resistant inner layer, it can not only effectively resist the erosion of the inner layer by corrosive media such as acids, alkalis, and solvents, preventing material oxidation and degradation, but also block aging and cracking problems caused by ultraviolet radiation, ensuring that the inner layer maintains its structural integrity for a long time. This fundamentally reduces the frequency of pipeline maintenance and replacement due to corrosion damage, and significantly extends the overall service life of the pipeline.
Owner:TUOHONG PIPELINE MATERIALS (KUNSHAN) CO LTD

Lycopene water dispersible powder and preparation method thereof

PendingCN121942900AHigh embedding ratereduce lossFood shapingBiotechnologyLycopersene
The invention relates to lycopene water dispersible powder and a preparation method thereof, and belongs to the technical field of food additives. The method comprises the following steps: esterifying octadecyl alcohol and food-grade phosphoric acid, and reacting with edible gelatin to prepare modified edible gelatin; then lycopene dry powder is dispersed in ethyl acetate, a compound emulsifier, modified edible gelatin and 1, 3-propylene glycol are added, and preliminary embedding is achieved through high-speed shearing and ultrasonic nanocrystallization treatment; and step-by-step vacuum drying, secondary embedding with an excipient, freezing, crushing and screening are carried out, such that the water dispersible powder with a particle size of 0.1-0.2 mm is prepared. Through the hydrophobic binding and charge repulsion effects of the modified gelatin and the synergistic process of ultrasonic nanocrystallization and double embedding, the technical problems that traditional lycopene is poor in water dispersibility, prone to layering, high in solvent residue and insufficient in stability are solved. The prepared product is suitable for healthy food systems such as water-based food, beverage and the like, and has the advantages of convenience in storage and transportation and high bioavailability.
Owner:XINJIANG KEYU TECH

High-temperature-resistant hot melt adhesive and preparation method thereof

The invention discloses a high-temperature-resistant hot melt adhesive and a preparation method thereof, and relates to the technical field of hot melt adhesives. The high-temperature-resistant hot melt adhesive is prepared from the following raw materials in parts by weight: 25 to 35 parts of modified polyimide resin, 20 to 30 parts of modified benzoxazine resin, 8 to 12 parts of carboxyl-terminated nitrile rubber, 5 to 8 parts of C5 / C9 copolymerized petroleum resin, 3 to 5 parts of hydrophobic modified nano silicon dioxide, 1 to 2 parts of silicone powder, 0.5 to 1.0 part of antioxidant 1010, 0.3 to 0.8 part of zinc stearate and 0.05 to 0.1 part of tetrabutylammonium bromide. The high-temperature-resistant hot melt adhesive is scientific in raw material ratio, core resin is modified to improve heat resistance and compatibility, filler such as hydrophobic nano silicon dioxide is added to enhance performance, the preparation process is controllable, nitrogen protection is achieved in the whole process, moisture absorption is prevented through granulation and drying treatment, and a finished product is excellent in high-temperature resistance, good in comprehensive performance and good in storage stability.
Owner:KUNSHAN TAITIAN NEW MATERIAL CO LTD

Ceftriaxone sodium powder injection and preparation method thereof

The invention belongs to the technical field of medicines, and particularly relates to a ceftriaxone sodium powder injection and a preparation method thereof. According to the invention, the water-soluble vitamin E and the L-cysteine are used for synergistically exerting anti-oxidation and anti-agglomeration effects, so that the agglomeration phenomenon in the polymer generation and crystallization process is effectively inhibited; chitosan modified mesoporous silica is adopted as a drug carrier, and drugs are promoted to orderly enter mesoporous channels through positive charge mediation, so that efficient loading of the drugs is realized, and biocompatibility is improved; by utilizing a supercritical anti-solvent crystallization technology, the drug is crystallized in situ in a mesoporous channel to form a highly dispersed state, and the specific surface area of the drug is obviously increased, so that the ultra-fast dissolution is realized; the ceftriaxone sodium powder injection prepared by the invention has the excellent characteristics of high dissolution speed, uniform particle size, no agglomeration, good stability, high safety and high drug loading efficiency.
Owner:SHANDONG ERYE PHARM CO LTD

Cleaning solution for allergen acridinium ester chemiluminescent immunoassay, its preparation method and application

PendingCN122468959AReduce non-specific adsorptionEfficient removalHemolysisActive agent
The application belongs to the technical field of in vitro diagnostic reagents, and discloses a cleaning solution for acridinium ester chemiluminescence immunoassay of allergens, a preparation method and application thereof. The cleaning solution is composed of HEPES buffer, a triple surfactant system (poloxamer 188, sodium deoxycholate and octyldecyl glucoside), glycerol, PEG8000, disodium EDTA and a composite preservative of Proclin 950 and BHT. The triple surfactant synergistic system is adopted to reduce non-specific adsorption, the HEPES weak alkaline buffer system avoids the inhibition of phosphates on acridinium ester luminescence, and the composite preservative system solves the toxicity and stability problems of traditional preservatives. The cleaning solution can significantly reduce the background luminescence value, the inhibition rate of hemolysis / lipemia / jaundice interference is less than 5%, the detection accuracy deviation is within ±5% (r>0.99), the precision is less than 3.5%, and the room temperature stability is more than 13 months, and the comprehensive performance is better than that of the commercially available products.
Owner:ANKERUI (SHANXI) BIOLOGICAL CELL CO LTD

A composition for repairing the lipid barrier and its use in sensitive skin care

This invention relates to a composition for repairing the lipid barrier and its application in sensitive skin care, belonging to the field of cosmetic technology. The composition includes *Plasmodium purpureus* extract, flaxseed extract, senna-based glycosides, and oat extract. The rational combination of these four components not only promotes lipid synthesis but also ensures effective lipid transport and prevents the oxidative degradation of newly synthesized lipids. By covering the entire lipid metabolism process, it achieves a long-lasting and stable barrier repair effect, and can be applied to the repair of the lipid barrier in people with sensitive skin. Efficacy testing shows that the *Plasmodium purpureus* extract, flaxseed extract, senna-based glycosides, and oat extract in the composition can synergistically enhance the composition's antioxidant and lipid synthesis-promoting capabilities, while effectively promoting skin barrier repair and increasing skin moisture content, exhibiting significant skin-soothing and repairing effects, making it highly suitable for people with sensitive skin.
Owner:N O D TOPIA (GUANGZHOU) BIOTECHNOLOGY CO LTD

High toughness thermal insulation epoxy resin, composite material and preparation method thereof

ActiveCN121610034Bavoid oxidative degradationlow thermal conductivity
This invention provides a high-toughness thermal insulation epoxy resin, a composite material, and a method for preparing the same. The high-toughness thermal insulation epoxy resin is prepared from raw materials comprising: component A and component B; the mass ratio of component A to component B is 95~150:80~120; component A comprises: 62~150 parts epoxy resin and 8~15 parts toughening agent; component B comprises: 25~45 parts curing agent, 0.3~0.8 parts antioxidant, 12~28 parts additives, and 32~50 parts lightweight filler; the additives are at least one of nano-titanium dioxide and silicon-titanium stacked composite microspheres. The addition of additives to this epoxy resin and composite material allows for synergistic effects with the low thermal conductivity of the lightweight filler, achieving high-efficiency thermal insulation. The additives also absorb energy through interlayer slip and strengthen interfacial bonding through hydrogen bonding with the epoxy resin matrix and glass microspheres, improving the material's mechanical properties. Furthermore, the addition of toughening agents and antioxidants enhances the mechanical properties and anti-aging properties of the composite material.
Owner:TIANJIN ISTAR ADVANCED MATERIAL TECH CO LTD

Graded preparation method and application of antibacterial active components based on multi-color mango peel residues

The invention relates to a graded preparation method of bacteriostatic active components based on multi-color mango peel residues, which comprises the following steps: crushing dried mango peel residues, and carrying out enzymolysis pretreatment by using a compound enzyme system containing cellulase and pectinase; carrying out ultrasonic-assisted extraction by adopting a deep eutectic solvent in which the molar ratio of choline chloride to glycerol is 1: 2, and carrying out centrifugal separation to obtain a crude extract; loading the crude extract on a macroporous adsorption resin column, carrying out gradient elution by using an ethanol-water solution containing 1-3% of hydroxypropyl-beta-cyclodextrin as a protective eluent, and collecting an active fraction; and directly cutting the active fraction into a preparative high performance liquid chromatography system by adopting a column switching technology, collecting a chromatographic peak with the retention time of 14.5-15.5 minutes, and volatilizing a solvent to obtain the targeted malassezia-resistant active component. The method can be used for preparing medicines or cosmetics for inhibiting malassezia.
Owner:BAISE UNIV

A raw material extraction device for detecting anthocyanin content of pure rice breeding material

PendingCN122282374Aefficient separationRealize automatic grindingAgricultural engineeringBroken rice
This invention discloses a raw material extraction device for detecting anthocyanin content in pure black rice breeding materials, relating to the field of anthocyanin extraction technology in pure black rice breeding materials. The device includes a main structure comprising an extraction tank. A support is fixedly installed on the bottom surface of the extraction tank, and a tank lid is fixedly installed on the upper surface of the extraction tank. A discharge pipe is fixedly connected to the bottom of the extraction tank, and an extraction processing mechanism is provided on the outside of the extraction tank. This raw material extraction device for detecting anthocyanin content in pure black rice breeding materials, through a grinding and air separation unit, can precisely grind the pure black rice breeding materials using grinding rollers, efficiently separating the rice husks from the rice grains. After filtration through a filter screen, the pure rice grains and seed coats enter the extraction tank through the husks, while the broken rice husk impurities are discharged through the discharge chamber. This achieves automated grinding, screening, and conveying of the raw materials, effectively solving the problem of rice husks hindering the contact between the extraction solvent and anthocyanins.
Owner:FOOD CROPS RES INST YUNNAN ACAD OF AGRI SCI +3

Submerged fermentation extraction process method of ganoderma triterpenic acid

The invention belongs to the technical field of biological fermentation, and particularly relates to a submerged fermentation extraction process method of ganoderma triterpenic acid. Preparing to obtain a seed solution; preparing a fermentation culture medium, and performing two-stage submerged fermentation on the seed solution to obtain a fermentation solution; filtering and separating the fermentation liquor to obtain mycelia containing intracellular ganoderma triterpenic acid and supernate containing extracellular ganoderma triterpenic acid, drying and crushing the mycelia, and carrying out ultrasonic and enzymolysis synergistic extraction to obtain an extracting solution; mixing the supernate and the extracting solution, filtering to obtain a clear solution, and purifying, concentrating and drying the clear solution to obtain a ganoderma triterpenic acid refined product. The method solves the problem of low yield of ganoderma triterpenic acid caused by uniform mycelium growth and ganoderma triterpenic acid synthesis environment, insufficient carbon source supply and limited induction effect in traditional submerged fermentation through innovative combination of staged fermentation, a fermentation composite carbon source, a composite inducer and beta-cyclodextrin.
Owner:杭州玥洋生物科技有限公司