The invention discloses a high-quality high-yield dragon fruit control-release fertilizer, which comprises the following raw materials including fertilizer particles and covering films, wherein the fertilizer particles are prepared from the following raw materials including cow manure, chicken manure, pig manure, waste slag, earthworm powder, compound bacteria, trace elements, water-retaining agents, dispersing agents, conditioning agents, seeping agents, regulating agents and tackifiers; the covering films are prepared from the following raw materials including animal glue, silicon carbide fiber, sodium phosphate, dampproof agents, oxidizing agents, coupling agents, cold-resistant agents, waterproof agents, synergists, seeping agents, flocculation agents, alkaline white soil, sludge and ammonium nitrate. The high-quality high-yield dragon fruit control-release fertilizer has the advantages that the control release speed is proper and stable; the fertilizer particle nutrition is balanced; the loss rate of the fertilizers can be effectively reduced; the utilization efficiency of the fertilizer is improved; the fast and health growth of the dragon fruit is promoted; the yield and the sugar content of the dragon fruit are improved. The high-quality high-yield dragon fruit control-release fertilizer provided by the invention has the advantages that the plant diseases and insect pests can be effectively prevented; the growth period can be shortened; the crop yield is improved; in addition, the soil environment can be improved.