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Compound fructus crataegi-turmeric root tuber particle and preparation method thereof

A technology of gold granules and compound recipes, which is applied in the direction of anti-toxins, pharmaceutical formulas, and medical preparations containing active ingredients, etc., can solve the problems of non-alcoholic steatohepatitis traditional Chinese medicine granules, such as the limited research and application, to block cell Effects of Factor Network, Lowering Blood Lipid, and Anti-inflammatory Liver Pathology

Inactive Publication Date: 2012-07-11
施军平
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

More than 400 well-known Chinese medicine hospitals in more than 30 provinces and cities in my country have used traditional Chinese medicine formula granules, but the research and application of traditional Chinese medicine granules for the treatment of non-alcoholic steatohepatitis is still not much

Method used

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  • Compound fructus crataegi-turmeric root tuber particle and preparation method thereof
  • Compound fructus crataegi-turmeric root tuber particle and preparation method thereof
  • Compound fructus crataegi-turmeric root tuber particle and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] A compound hawthorn granule is prepared from the following raw materials in parts by weight: 130g of hawthorn, 90g of curcuma, 60g of Alisma, 120g of seaweed, 60g of elephant shellfish, 120g of milk thistle and 40g of peach kernel.

[0018] The preparation method of compound zhajin granule, it comprises following concrete steps:

[0019] (1) Weigh hawthorn, turmeric, Alisma, seaweed, elephant shellfish, milk thistle and peach kernel according to the above weight parts, and then add water to soak for 30 minutes;

[0020] (2) Micropowder silica gel is selected as a single auxiliary material for spray drying, and lactose is an auxiliary material for granulation, which is stored separately for subsequent use;

[0021] (3) Add 4 to 10 times the amount of water to the raw material drug soaked in step (1) for the first time, decoct for 20 minutes, add 4 to 10 times the amount of water for the second time, and decoct for 30 minutes. The amount of water added twice is optimal B...

Embodiment 2

[0033] A compound hawthorn granule is prepared from the following raw materials in parts by weight: 170g of hawthorn, 60g of curcuma, 90g of Alisma, 80g of seaweed, 90g of elephant shellfish, 80g of milk thistle and 60g of peach kernel.

[0034] The preparation method is the same as in Example 1.

Embodiment 3

[0036] A compound hawthorn granule, which is prepared from the following raw materials in parts by weight: 150g of hawthorn, 75g of turmeric, 75g of Alisma, 100g of seaweed, 75g of elephant shellfish, 100g of milk thistle, and 50g of peach kernel.

[0037] The preparation method is the same as in Example 1.

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Abstract

The invention relates to a compound fructus crataegi-turmeric root tuber particle, which is prepared from the following bulk pharmaceuticals in parts by weight: 130-170 parts of fructus crataegi, 60-90 parts of turmeric root tuber, 60-90 parts of oriental waterplantain rhizome, 80-120 parts of seaweed, 60-90 parts of bulb of thunberg fritillary, 80-120 parts of milk thistle and 40-60 parts of peach kernel. The invention further provides a preparation method for the compound fructus crataegi-turmeric root tuber particle. The method comprises the following steps of: weighing fructus crataegi, turmeric root tuber, oriental waterplantain rhizome, seaweed, bulb of thunberg fritillary, milk thistle and peach kernel according to parts by weight, and adding water for soaking; preparing micro-powder silica gel serving as a single auxiliary material of spray drying and lactose serving as an auxiliary material of particle forming, and standing for later use; adding water in an amount which is 4-10 times that of soaked Chinese medicinal materials including fructus crataegi, turmeric root tuber, oriental waterplantain rhizome, seaweed, bulb of thunberg fritillary, milk thistle and peach kernel for a first time, adding water in an amount which is 4-10 times that of the Chinese medicinal materials for a second time, and decocting; concentrating an obtained compound extract till the relative density is 1.065, adding an auxiliary material, i.e., micro-powder silica gel, performing spraying drying to obtain extract powder; and adding lactose and ethanol into the extract powder, uniformly mixing, granulating, drying and regulating particles.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to compound zhajin granules which can be used for medically treating simple fatty liver and steatohepatitis diseases and a preparation method thereof. Background technique [0002] In recent years, a series of clinical and experimental studies have been conducted on the anti-nonalcoholic steatohepatitis of the principle Qihuatan Quyu formula (composed of hawthorn, turmeric, peach kernel, Alisma, seaweed, elephant shellfish, and citron), and it was found that regulating qi Huatan Quyu Prescription can significantly improve insulin sensitivity, imaging and serum enzyme indexes of NASH patients, and can significantly improve clinical symptoms such as fatigue and liver pain; animal experiments have shown that this prescription has a positive effect on the insulin signaling network in NASH rats. Extensive regulation can significantly reduce the liver peroxisome proliferator...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/16A61P1/16A61P3/06A61P39/06
Inventor 施军平
Owner 施军平
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