325results about How to "Alleviate the condition" patented technology

A system that facilitates device and/or machinery diagnostics, prognostics and control by way of condition sensing, such as sensing the condition of the device and/or a fluid of the device (e.g., fluid health indicators). The system can employ a plurality of sensors to determine a current state and estimate a future state of the fluid and/or device, as well as providing control of the device, e.g., in order to increase the remaining useful life of the fluid and/or operation of the device. The sensors can communicate wirelessly with each other, with the device, and/or with a central control system that provides, e.g., sensor fusion, prognostics and control integration. In addition, the sensors can be powered locally based upon the physical or chemical properties of the environment.

The present invention discloses a PFC-PWM controller having interleaved switching. A PFC stage generates a PFC signal for switching a PFC boost converter of a power converter. A PWM stage generates a PWM signal for switching a DC-to-DC converter of the power converter. The PFC-PWM controller includes a power manager for generating a discharge current and a burst-signal. Under light-load conditions, the discharge current decreases in proportion to a load of the power converter. The burst signal is utilized to disable the PFC signal in a suspended condition for power saving. A pulse width of the pulse-signal ensures a dead time to spread switching signals, such as the PFC and PWM signals, and reduces switching noise. When the discharge current decreases, the pulse width of the pulse-signal will increase and a frequency of the pulse-signal will decrease correspondingly. This further reduces power consumption under light-load and zero-load conditions.

An electrically-variable transmission for use with an engine includes an input member configured for operative interconnection with the engine, an output member, and a stationary member. First and second motor/generators, a first and a second planetary gear set each having respective first, second, and third members are included. A first, a second, and a third selectively engagable torque-transmitting mechanism are included. The input member is connectable for common rotation with the first member of the first planetary gear set either continuously or selectively by engagement of the third torque-transmitting mechanism. The output member is connected for common rotation with the first member of the second planetary gear set. The motor/generators are controllable and the torque-transmitting mechanisms are selectively engagable to establish at least one electric-only mode, a series mode, an output-split mode, and at least one neutral mode.

The invention provides a method and system for continuous optimization of a data center. The method includes monitoring loads of storage modules, server modules and switch modules in the data center, detecting an overload condition upon a load exceeding a load threshold, combining server and storage virtualization to address storage overloads by planning allocation migration between the storage modules, to address server overloads by planning allocation migration between the server modules, to address switch overloads by planning allocation migration mix between server modules and storage modules for overload reduction, and orchestrating the planned allocation migration to reduce the overload condition in the data center.

The invention discloses a method for carrying out in-situ repairing on blood coagulation factor F8/F9. The method comprises the following steps: in a target genome sequence, selecting the mutation sites of blood coagulation factor as the gene sites for in-situ repairing; designing the binding sites of nuclease of sgRNA sequence of a CRISPR/Cas system; designing a homologous recombinant repairing donor sequence for in-situ repairing; delivering nuclease protein and/or sgRNA and the nucleotide sequence of the homologous recombinant repairing donor to the gene sites of in-situ repairing by a delivering carrier; generating damages to the genome DNA by the nuclease on the gene in-situ repairing sites; and inserting the homologous recombinant repairing donor sequence into the gene in-situ repairing sites so as to repair the gene or supplement the expression of gene. The in-situ repairing of mutation sites of blood coagulation factor can be applied to the clinic, and the method has the advantages of precise induction, safer and controllable process, and definite target.

An intelligent turn signal control system for turning on and off left and right turn signals in a vehicle includes a computer, such as an antilock braking system computer, with programmed software operably disposed on a vehicle, a driver interface switch assembly as input to the computer. Two or more wheel speed sensors transmit differential wheel movement data as input to the computer, a circuit drives turn signal indicator lamps from conditionally computed output data from the computer to turn on and off turn signals in a situation-appropriate manner. Upon turn signal indication intent data input from the driver, extensive travel and turn data is computed, including yaw rotation and steering system position to turn off or cancel the turn signal at the appropriate point.

An energy dissipating helmet, such as a football, baseball, hockey, construction, combat, bicycle, or motorcycle helmet, including a structural component adapted to receive an anticipatory impact having energy, and a stress-activated active material element, such as a Austenitic shape memory alloy wire, mesh, layer, or spring, communicatively coupled to the component, and activatable by the impact, so as to dissipate at least a portion of the energy.

The invention relates to methods of modulating immune cells in a patient by altering microbiota of the patient. The invention also relates to methods of modulating treatments or therapies in a subject organism by altering microbiota of the subject. The invention also relates to cell populations, systems, arrays, cells, RNA, kits and other means for effecting this. In an example, advantageously selective targeting of a particular species in a human gut microbiota using guided nucleic acid modification is carried out to effect the alteration.

A work station comprises a base. A seat and a tower are each cooperatively connected to the base thereby providing an adjustable interaction between the seat and the tower. The tower supports a keyboard support and the seat has an armrest for supporting an occupant. At least one armrest adjustment device is disposed between the seat and the armrest and is moveable between an unlocked position to allow for adjustment of the armrest relative to the seat to an ergonomically correct position relative to the keyboard support and to a locked position to lock the armrest in the ergonomically correct position. An armrest lever is operatively connected to the at least one armrest adjustment device to move the at least one armrest adjustment device between the unlocked position and the locked position.

Systems and methods of the invention relate to treatment of a health condition, and particular, a respiratory health condition, through the use of a personalized, technology agnostic kits for tracking of specific health and/or wellness parameters, sharing parameters, and distributing health and/or wellness advice between a treatment provider and a user. A treatment provider can communicate medical advice and/or health advice to manage the condition of a user based on data representative of parameter(s) that can affect the condition. The user can select one or more devices that collect data related to the parameter(s) and a secure channel is used to communicate such data to the treatment provider that is handling the condition to allow for communicating the medical advice and/or health advice.

A subject of the present invention is to provide a door handle device capable of controlling its opening/closing action by using a piezoelectric sensor that has a flexible structure and can attain an enough sensitivity even by a light touch, and a keyless entry system having the same.

A door handle device (100) that is able to open a lock of a door locking means, which is provided to a door (13) with a handle (11) used for an opening/closing operation to lock an opening operation of the door (13), by an operation of the handle, includes a piezoelectric sensor (15) formed of a piezoelectric element fitted to the handle (11) and having a flexibility, and a controlling portion for receiving a sensed signal of the piezoelectric sensor (15) generated by a touch on the handle (11) to open the lock of the door locking means.

The present invention provides methods and compositions for expanding T regulatory cells ex vivo or in vivo using one or more SAP agonists. The methods and compositions are useful in the treatment of autoimmune diseases and in preventing foreign graft rejection.

The establishment and reception of a service, such as a multimedia service, over different networks is described. A first and second network coupled by a home gateway may respectively employ first and second radio access technologies. An interface between the radio access technologies may communicate downlink channel setup requests. Uplink and downlink control signals are communicated via a first network. In response to the exchange of uplink and downlink control signals via a first network, multimedia data is received via the second network.

A thermal fluid flow sensor and method of forming same. The flow sensor has an integrated circuit substrate, such as a silicon substrate, and a region of low thermal conductivity material carried on the top surface of the integrated circuit substrate. One or more pairs of temperature sensing elements are disposed on the low thermal conductivity region together with a heating element so that a robust flow sensor can be provided at low cost. Signal conditioning circuitry is disposed on the same surface as the temperature sensing elements and connected to the sensing elements thereby further reducing costs and improving the flow sensor sensitivity.

The present invention provides a compound of formula I:

or a pharmaceutically acceptable derivative thereof. These compounds are inhibitors of protein kinases, particularly inhibitors of GSK3 mammalian protein kinase. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of utilizing those compounds and compositions in the treatment of various protein kinase mediated disorders.

Methods and compositions containing bicifadine are provided for the treatment and prevention of hyperthermia in mammalian subjects. The methods and compositions may be used to prevent or treat fever, pyresis, menopausal hot flashes; peri menopausal hot flashes, postmenopausal hot flashes, hot flashes caused by anti-estrogen therapy, hot flashes secondary to surgical removal of estrogen producing tissue, hot flashes caused by radiation therapy, malignant hyperthermia, serotonin syndrome, heat stroke, febrile seizures, and neuroleptic malignant syndrome, among other conditions. Additional compositions and methods are provided employing bicifadine to treat pyresis and simultaneously elicit an analgesic response in mammalian subjects. Yet additional compositions and methods are provided which employ bicifadine in combination with a second antipyretic agent, a second analgesic agent, or a different therapeutic agent to yield more effective antipyretic treatment tools, and/or dual activity therapeutic methods and formulations useful to prevent or reduce hyperthermia and one or more additional symptoms (e.g., pain, or depression) in mammalian subjects.

The production yield about defect free devices is improved by so controlling the size and density of void defects that they are under predetermined levels without marring the productivity. The pull-up speed V of a silicon crystal (10) by a pull-up mechanism (4) is controlled, and the rate of cooling by a cooler (30) is also controlled. As a result, the axial temperature gradient G₁ at and near the melting point of the silicon crystal (10) is increased. The growth condition V/G₁ is lowered to a temperature near the critical value under the condition that the growth rate V lies in the range from 97% to 75% of the limit rate Vmax and that the solid-liquid interface is convex with respect to the melt surface. Thus a silicon crystal (10) is grown by pulling up.

The present invention features a unique, natural formulation and method of administering the same to treat and prevent diabetes, or rather advances treatment of diabetes, by providing a nutraceutical composition or treatment formulated with one or more processed Morinda citrifolia products, including TAHITIAN NONI® juice and juice concentrate, as derived from the Indian Mulberry plant.

A formation treatment tool assembly is conveyed within a well casing by a tubing string and has a housing defining treatment fluid supply and discharge passages and a fluid injection port through which treatment fluid is directed from the supply passage into a packer isolated casing interval and a fluid inlet port permitting flow from the isolated casing interval to the fluid discharge passage. Spaced straddle packer elements of the tool are energized to establish sealing engagement with the well casing and define an isolated casing interval and are de-energized to retract from sealing engagement with the well casing and permit tubing conveyance. A dump valve connected with the tool housing is opened to permit flow of treatment fluid from the isolated casing interval through the treatment fluid discharge passage and is closed to confine treatment fluid to the isolated casing interval. A hydraulic or mechanically actuated tubing isolation valve is selectively closed to isolate the tubing string from casing or formation pressure and permit tool conveyance while maximizing the service life of the tubing string and to accommodate overpressured and underbalanced reservoir conditions.

An infusor system for administering medications to a venous blood vessel in the body of a patient. The infusor system includes a flexible, elongated delivery tube having opposite ends. One of the ends is couplable to a supply of liquid medication, which is remote from the venous blood vessel. The system further includes a delivery component coupled to the other end of the delivery tube. This delivery component is adaptable to be placed in confronting relationship with the venous blood vessel so that medication from said supply may be introduced directly into the venous blood vessel and distributed in the body of the patient. The infusor system further includes a pressure-altering device used for increasing intraabdominal pressure in the body of the patient. Sampling of venous blood from the meningorrhachidian vasculature is also possible.

The electric highway includes at least one electrified lane that may be separated from other non-electrified lanes by a non-elevated strip of dividers, a roadside subsystem that includes a system operation monitoring center that monitors system operation; a plurality of roadside conductor assemblies, each of which includes at least one roadside conductor laid within a coaxial pipe made of a non-magnet field shielding material, and its/their housing in the traffic lane; a roadside part of an on-board part of a lateral location sensor; a plurality of roadside controller each of which includes a power supply assembly, at least one communication device housed in a roadside box, and a plurality of roadside posts with a camera affixed to it. The electric highway system is monitored continuously at the system operation monitoring center.

A technique triggers packing of path computation requests (PCRs) for traffic engineering (TE) label switched paths (LSPs) that are sent from one or more label-switched routers (LSRs) to a path computation element (PCE) of a computer network. According to the novel technique, incoming PCRs are packed into sets in response to a certain event, and one or more TE-LSPs (paths) are computed for each PCR of a particular set based on the PCRs of that set. Specifically, the PCE detects an event in the network (“network event”) indicating that an increase in the number of incoming PCRs has occurred, or that an increase is likely to occur due to, e.g., a change in a network element. Once the net-work event has been detected, the PCE packs the incoming PCRs into configured-length sets, such as, e.g., for a specified time interval or a certain number of PCRs. The PCE computes paths for each PCR of a particular set while considering the other PCRs of that set, thereby reducing race conditions, signaling overhead, and set-up failures.

A computer compressed memory system for storing and retrieving data in a processing system, includes a memory including at least one memory device for storing at least one of uncompressed data and compressed data, a compressor for encoding data blocks into smaller compressed data blocks for storage in the memory, a decompressor for reconstituting encoded data into original uncompressed data blocks, a memory controller for generating, receiving and responding to memory access requests from processing and input/output units and responsively controlling access to the memory from the compressor and the decompressor for storing and retrieving data, and a hardware priority filter associated with the memory controller for selecting specific memory access requests according to attributes and access type within prescribed rates and under specific conditions.