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Chinese medicinal preparation for treating vaginitis and preparation method thereof

A technology of traditional Chinese medicine preparations and vaginitis, applied in the field of pharmaceutical preparations, can solve problems such as difficult to completely cure diseases, large loss of medicinal liquid, and inability to maintain long-term effects

Active Publication Date: 2012-07-18
陕西步长高新制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

During the actual experimental research, we found that the single herb of Hawthorn has unexpected therapeutic effects on vaginitis caused by various reasons. Therefore, we applied for the application number 03139655.0 on June 26, 2003 The invention patent was obtained after that, and the patent document is mainly protected from the aspects of prescription ratio and lotion. However, because the vaginal lotion formulation itself belongs to local application, it is inconvenient to use and the loss of liquid medicine is large, so it cannot be maintained. Shortcomings such as long-term effect and difficult to completely cure the disease, which lead to its influence on the promotion and use of the drug itself to a certain extent

Method used

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  • Chinese medicinal preparation for treating vaginitis and preparation method thereof
  • Chinese medicinal preparation for treating vaginitis and preparation method thereof
  • Chinese medicinal preparation for treating vaginitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0090] (1) Take 1170g of hawthorn core, pulverize it, add water with a weight ratio of 8 times that of the medicinal material, and soak for 30 minutes with a pH value of 4.0, heat and reflux for extraction for 2 hours, filter, and keep the filtrate for use; 6 times the water with a pH value of 6.5, heated and refluxed for 1.5 hours, filtered, and the filtrate was kept for use; the water with a weight ratio of 5 times that of the medicinal material and a pH value of 8.0 was added to the medicinal residue, heated and refluxed for 1 hour, filtered, The filtrate is retained;

[0091] (2) Combine the filtrates obtained in the above (1), concentrate under reduced pressure to a relative density of 1.1, add ethanol to make the alcohol content 60%, refrigerate for 24 hours, and centrifuge at 2000r / min, and recover ethanol from the centrifuge under reduced pressure Concentrate and dry, pulverize into dry cream powder, add antiseptic and corrective agent, add water and adjust to 1000ml, ...

Embodiment 2

[0093] (1) Take 1170g of hawthorn core, pulverize it, add water with a weight ratio of 6 times that of the medicinal material, and soak for 40 minutes with a pH value of 3.0, heat and reflux for extraction for 3 hours, filter, and keep the filtrate for use; 8 times water with a pH value of 7.0, heated and refluxed for 2 hours, filtered, and the filtrate was kept for use; water with a weight ratio of 4 times that of the medicinal material and a pH value of 7.5 was added to the medicinal residue, heated and refluxed for 0.5 hours, filtered, The filtrate is retained;

[0094] (2) Combine the filtrates obtained in the above (1), concentrate under reduced pressure to a relative density of 1.0, add ethanol to make the alcohol content 80%, refrigerate for 12 hours, and centrifuge at 1000r / min, and recover ethanol from the centrifuge under reduced pressure Concentrate and dry, crush into dry cream powder, mix with 100 mesh compressible starch, take out 25% of the mixed powder for late...

Embodiment 3

[0096] (1) Take 1170g of hawthorn core, pulverize it, add water with a weight ratio of 10 times that of the medicinal material, and soak for 20 minutes with a pH value of 5.5, heat and reflux for extraction for 1.5 hours, filter, and keep the filtrate for use; 5 times the water with a pH value of 6.0, heated and refluxed for 1 hour, filtered, and the filtrate was retained; the water with a weight ratio of 6 times the medicinal material and a pH value of 8.5 was added to the medicinal residue, heated and refluxed for 2 hours, filtered, The filtrate is retained;

[0097] (2) Combine the filtrates obtained in the above (1), concentrate under reduced pressure to a relative density of 1.2, add ethanol to make the alcohol content 50%, refrigerate for 36 hours, and centrifuge at 3000r / min, and recover ethanol from the centrifuge under reduced pressure Concentrate and dry, pulverize into dry cream powder, granulate, dry, and make 1000g, obtain the granule of the present invention.

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Abstract

The invention relates to a Chinese medicinal preparation for treating vaginitis and a preparation method thereof. The Chinese medicinal preparation is an oral Chinese medicinal preparation prepared by extracting and purifying Chinese hawthorn seed serving as a raw material according to a certain process and adding pharmaceutically-acceptable auxiliary materials. The Chinese medicinal preparation has the characteristics that a preparation process is simple, feasible, safe and effective, and a pharmacological effect and a medicinal effect are obvious.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation for treating vaginitis and a preparation method thereof, belonging to the technical field of medical preparations. Background technique [0002] Vaginitis is a common and frequently-occurring disease in women's reproductive system inflammation. The main symptoms are increased leukorrhea, pruritus vulvae or accompanied by scorching heat in the vulva, which belongs to the scope of leukorrhea and pruritus vulvae in the motherland's medicine. The etiology is mostly negligence of hygiene, infection of vaginal worms, or damp-heat betting, accumulation of stagnation and worms, or spleen deficiency and damp resistance, dampness and turbidity overflowing the lower energizer, hurting the two veins of the kidney, or liver and kidney yin deficiency, dryness and wind, or Stagnation of heart and liver qi, long-term fire of stagnation caused by disturbing the meridians. Modern Western medicine belie...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/734A61P15/02
Inventor 赵涛卢露谢伟
Owner 陕西步长高新制药有限公司
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