The embodiment of the invention further discloses an externally applied medicinal liquor for treating arthralgia and a preparation method thereof, and belongs to the technical field of medicines. Theexternally applied medicinal liquor is prepared from pericarpium zanthoxyli, the root of single roxburgh rose, wild loquat roots, long-noded pit viper, the bark of eucommia, ground beeltle, rhizoma polygoni cuspidati, rhizoma curcumae longae, radix cynanchi panicullati, rhizoma chuanxiong, trogopterus dung, olibanum, myrrh, teasel roots, herba taxilli, the root of bidentate achyranthes, medulla tetrapanacis, rhizoma drynariae, rhizoma cibotii, the bark of ash, rhizoma gastrodiae, cassia twigs, rhizoma sinomeni cauliset, radix clematidis, fructus chaenomelis, radix angelicae pubescentis, notopterygium roots, the suberect spatholobus stem, sanguis draxonis, radix aconiti, cortex acanthopanacis, herba asari cum radice, resina liquidambaris, borneol and ethyl alcohol. All the medicine materials are combined to achieve the effects of promoting blood circulation to remove blood stasis, dredging collaterals to dispel cold, drawing out poison to relieve swelling and pain, and a good effect ontreatment of the arthralgia is achieved. The externally applied medicinal liquor is free of irritation to skin and high in safety, has few obvious toxic and side effects and is wide in application prospect.