Medicinal composition for treating acquired immune deficiency syndrome (Aids) as well as preparation method, quality control method and application thereof

A composition and drug technology, applied in the directions of drug delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problem that the curative effect needs to be improved, and achieve the improvement of the CD4+T cell ratio, the improvement of the quality of life, and the improvement of the count level. Effect

Active Publication Date: 2014-01-15
GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, its efficacy still needs to be improved

Method used

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  • Medicinal composition for treating acquired immune deficiency syndrome (Aids) as well as preparation method, quality control method and application thereof
  • Medicinal composition for treating acquired immune deficiency syndrome (Aids) as well as preparation method, quality control method and application thereof
  • Medicinal composition for treating acquired immune deficiency syndrome (Aids) as well as preparation method, quality control method and application thereof

Examples

Experimental program
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Effect test

preparation example Construction

[0043] The preparation method of above-mentioned pharmaceutical composition, comprises the steps:

[0044] 1) Take the crude drug, decoct it with water, filter, and take the filtrate;

[0045] 2) centrifuging the filtrate, taking the supernatant, concentrating, and extracting the concentrate with water;

[0046] 3) adding ethanol to the concentrated water extract, stirring, standing still, and then centrifuging, taking the supernatant, removing ethanol, and obtaining the ethanol extract;

[0047] 4) Prepare the pharmaceutical preparation by combining the alcohol extract and other acceptable pharmaceutical excipients.

[0048] Furthermore, its preparation method includes the following steps:

[0049] 1) Take the raw material drug, add water to decoct 3 times, add 20 times the amount of water each time, decoct for 2 hours, let cool, filter, and combine the filtrate;

[0050] 2) Centrifuge the filtrate, take the supernatant and concentrate it to the weight of the raw material ...

Embodiment 1

[0072] Raw material composition:

[0073] 25 parts of cooked aconite, 12.5 parts of epimedium, 12.5 parts of dried ginger, 12.5 parts of licorice, 7.82 parts of red ginseng, 7.81 parts of poria cocos, 7.81 parts of knotweed, 7.81 parts of salvia miltiorrhiza, 3.75 parts of Phellodendron phellodendri, and 2.5 parts of skullcap.

Embodiment 2

[0075] Raw material composition:

[0076] 20 parts of cooked aconite, 14 parts of epimedium, 15 parts of dried ginger, 10 parts of licorice, 10 parts of red ginseng, 12 parts of poria cocos, 6 parts of knotweed, 10 parts of salvia miltiorrhiza, 5 parts of Phellodendron phellodendri, and 3 parts of skullcap.

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Abstract

A pharmaceutical composition for treating AIDS and preparation method, quality controlling method and use thereof. The raw material of the composition consists of Radix Aconiti Lateralis Preparata, Herba Epimedii, Rhizoma Zingiberis, Radix Glycyrrhizae, Radix Ginseng, Radix Salviae Miltiorrhizae, Rhizoma Polygoni Cuspidati, Poria, Cortex Phellodendri and Radix Scutellariae.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition for treating AIDS. The invention also relates to a quality control method and use of the composition. Background technique [0002] AIDS is an acquired immunodeficiency syndrome caused by HIV infection. The clinical manifestations of different stages of HIV infection process and pathogenesis are complex and diverse, including fatal malignant tumors and various opportunistic infections that occur later. [0003] People generally enter the onset period after 7-12 years after being infected with HIV-1. According to the current standard of diagnosis and treatment, antiviral therapy is not recommended for HIV carriers who are asymptomatic and whose CD+ T cell count has not been greatly reduced (for example, still above 300 per microliter), otherwise it will cause patients and society Take the huge risk of inducing severe drug resistance. According to the ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61P31/18
CPCA61K36/537A61K36/484A61K36/076A61K36/714A61K9/00A61K36/756A61K36/9068A61K36/539A61K36/296A61K36/704A61K36/258A61K9/4858A61P31/18A61K2300/00
Inventor 胡英杰符林春
Owner GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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