Method for extracting salicin from white willow bark

A technology of salicin and white willow, which is applied in the field of extraction and separation of plant active ingredients, can solve the problems of low extraction purity and low extraction rate, and achieve the effects of short extraction time, high extraction rate and good adsorption effect

Active Publication Date: 2015-04-22
DAXINGANLING LINGOBERRY BOREAL BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to overcome the shortcomings of conventional techniques such as relatively low extraction rate and low extraction purity, and to provide a method for purifying salicin in white willow bark using ultrasonic extraction-macroporous resin combination technology

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Embodiment 1: a kind of method utilizing ultrasonic extraction-macroporous resin combination technique to purify salicin in white willow bark, its steps are as follows:

[0018] (1) Crush 1 kg of white willow bark into 1-2 cm segments, mix with quicklime, the mass ratio is 1:8, and let stand for 10 minutes.

[0019] (2) The mixed raw materials were added with 80% ethanol solution, and extracted twice by ultrasonic wave, the ultrasonic power was 200W, the extraction time was 20min, the extraction temperature was 40°C, and the working mode was 5 seconds of work and 5 seconds of rest.

[0020] (3) The raw materials extracted by ultrasonic waves were extracted by reflux for 1 hour, extracted twice, filtered, and the extracts were combined.

[0021] (4) The extract is concentrated under reduced pressure, the pressure is controlled at 0.1 Mpa, the temperature is controlled at 50° C., and concentrated to no alcohol.

[0022] (5) Dilute the concentrated solution with 4 times o...

Embodiment example 2

[0026] Implementation case 2: A method for purifying salicin in white willow bark using ultrasonic extraction-macroporous resin combination technology, the steps are as follows:

[0027] (1) Crush 1 kg of white willow bark into 1 to 2 cm segments, mix with quicklime at a mass ratio of 1:10, and place for 10 minutes.

[0028] (2) The mixed raw materials are added with 90% ethanol solution, and extracted twice by ultrasonic wave, the ultrasonic power is 300W, the extraction time is 30min, the extraction temperature is 50°C, the working mode is 5 seconds, and the interval is 5 seconds.

[0029] (3) Raw materials extracted by ultrasonic waves were extracted by reflux for 1.5 hours, extracted twice, filtered, and combined extracts

[0030] (4) Concentrate the extract under reduced pressure, control the pressure at 0.15Mpa, control the temperature at 55°C, and concentrate until alcohol-free

[0031] (5) Dilute the concentrated solution with 5 times of water, let it stand for 1 hour...

Embodiment example 3

[0035] Implementation case 3: A method for purifying salicin in white willow bark using ultrasonic extraction-macroporous resin combination technology, the steps are as follows:

[0036] (1) Crush 1 kg of white willow bark into 1-2 cm segments, mix with quicklime, the mass ratio is 1:12, and let stand for 10 min.

[0037] (2) The mixed raw materials are added with ethanol solution with a concentration of 95%, and extracted twice by ultrasonic waves, the ultrasonic power is 400W, the extraction time is 10min, the extraction temperature is 60°C, and the working mode is 5 seconds of work and 5 seconds of rest.

[0038] (3) The raw materials extracted by ultrasonic waves were extracted by reflux for 2 hours, extracted twice, filtered, and the extracts were combined.

[0039] (4) The extract is concentrated under reduced pressure, the pressure is controlled at 0.2Mpa, the temperature is controlled at 60° C., and concentrated to no alcohol.

[0040] (5) Dilute the concentrated solu...

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PUM

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Abstract

The invention belongs to the technical field of extraction and separation of active ingredients from a plant, and specifically relates to a method for purifying salicin in white willow bark by using an ultrasonic extraction-macroporous resin combined technology. The method is characterized in that: the purpose of the method is to overcome disadvantages of relatively low extraction rate, low extraction purity and the like of the conventional technology, and to provide a method for purifying salicin in white willow bark by using an ultrasonic extraction-macroporous resin combined technology. The method has the following advantages that: the ultrasonic extraction is adopted, such that advantages of low extraction temperature, high efficiency, short extraction time, and the like are provided, the salicin extraction rate is substantially improved, and the extraction time is shortened; the macroporous resin is adopted to adsorb the salicin, such that the good adsorption effect on the salicin is provided; and an ethanol water solution is adopted to extract salicin, such that the dissolving effect is good, the salicin consumption is reduced, and the yield is increased.

Description

Technical field: [0001] The invention belongs to the extraction and separation technology of plant effective components, and in particular relates to a method for purifying salicin in white willow bark by using ultrasonic extraction-macroporous resin combination technology. Background technique: [0002] White willow is a deciduous tree, 10-12 meters high, with long and drooping branches, the lower branches are brown and glabrous, slightly hairy when young, the leaves are lanceolate or linear-lanceolate, 9-16cm long, 5-15cm wide , the apex is long and acuminate, can be harvested throughout the year, and used for bark. Born in waterside wetlands, it is cultivated all over the country. Mainly distributed in the Yangtze River Basin and South China. [0003] The white willow bark extract is a yellow powder, which has the functions of clearing heat and detoxifying, expelling wind and dampness, promoting blood circulation and removing blood stasis. The main ingredient with medi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C07H15/203C07H1/08
Inventor 姚德坤姚德利张亚红万莉
Owner DAXINGANLING LINGOBERRY BOREAL BIOTECH CO LTD
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