Application of (E)-2-(3,5-dimethoxybenzylidene)-cyclopentanone in preparing medicine for treating cerebrovascular diseases

A drug and ischemic stroke technology, applied in cardiovascular system diseases, drug combinations, nervous system diseases, etc.
CN102824336BInactive Publication Date: 2014-02-26SUZHOU UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SUZHOU UNIV
Publication Date
2014-02-26
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses application of (E)-2-(3,5-dimethoxybenzylidene)-cyclopentanone in preparing a medicine for treating cerebrovascular diseases. The related research indicates that the compound has an obvious cranial nerve protection effect, obviously reduces the focal cerebral ischemia rat cerebral infarction volume and remarkably improves the neurologic symptom. The (E)-2-(3,5-dimethoxybenzylidene)-cyclopentanone is used for preventing or treating the diseases such as ischemic brain injury, cerebral hemorrhage, cerebral thrombosis, cerebral embolism, cerebral infarction, cerebral apoplexy, lacunar infarction, transient ischemic attack, cerebral arteriosclerosis, diabetic cerebrovascular complications and the like.
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Description

technical field

[0001] The invention relates to the field of medicines, in particular to the application of (E)-2-(3,5-dimethoxybenzylidene)-cyclopentanone in the preparation of medicines for treating mammalian cerebrovascular diseases. Background technique

[0002] Cerebral stroke is a group of diseases whose main clinical manifestations are cerebral tissue ischemia and hemorrhagic injury symptoms, also known as stroke or cerebrovascular accident. The disease has an acute onset, high disability rate and high mortality rate, and is one of the most important diseases that endanger human health in the world today. Stroke is mainly divided into two categories: hemorrhagic stroke (cerebral hemorrhage or subarachnoid hemorrhage) and ischemic stroke (ischemic brain injury, including cerebral infarction and cerebral thrombosis). Stroke is the most common.

[0003] At present, the clinical treatment of ischemic stroke mainly adopts drug therapy, including thrombolysis, vasodilator...

Claims

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