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Powder of vitreous composition having biocidal activity

A technology of biocide and glass state, which is applied in the direction of biocide, animal repellent, plant growth regulator, etc., can solve the problem of not having biocidal activity, and achieve the effect of simple preparation method

Inactive Publication Date: 2012-12-19
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Furthermore, it is well known that glassy products with high silica content (e.g. laboratory glasses, bottles, etc.) do not have biocidal activity

Method used

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  • Powder of vitreous composition having biocidal activity
  • Powder of vitreous composition having biocidal activity
  • Powder of vitreous composition having biocidal activity

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Example 1. Bactericidal activity test against Gram-negative bacteria Escherichia coli

[0028] Three vitrified composition powders (average particle size less than 200 μm) with different compositions and high calcium content were subjected to biocide tests to evaluate their bactericidal activity against the Gram-negative bacterium Escherichia coli. In addition, a commercially available soda lime glass with a CaO content of less than 10% by weight (commonly used in the manufacture of windows and bottles) was also used for biocide testing in order to demonstrate that this glass does not have biocidal activity. The chemical analysis of these glasses is as follows:

[0029] 1. Glass A with 15% by weight of CaO.

[0030] This glass has the following chemical composition (% by weight): 47.6% SiO 2 ; 27.5% Na 2 O; 14.9% CaO; 1% K 2 O; 2% Al 2 o 3 ;6.9%B 2 o 3 ; and 1.9% of other substances.

[0031]2. Glass B with 20% by weight of CaO.

[0032] This glass has the fol...

Embodiment 2

[0044] Example 2. Bactericidal Activity Test Against Gram-Positive Bacteria Micrococcus Luteus

[0045] Following the previous procedure, biocide tests were performed against the three types of glass previously described against the Gram-positive bacterium M. luteus.

[0046] The results obtained, expressed as the logarithm of the reduction in colony-forming units (Table 2), show safe disinfection for all glasses (glasses A, B, C and bioglass) with a CaO content of more than 10 wt. After 48 hours of incubation, the log reduction in colony forming units was log[eta]>4. However, soda lime glass with a CaO content below 10% by weight did not show any biocidal activity.

[0047]

[0048] Table 2: Shows the log reduction in colony forming units of M. luteus after 24 and 48 hours of biocide testing.

Embodiment 3

[0049] Example 3. Biocide activity test against the yeast Candida krusei

[0050] Following the previous process, biocide tests were performed against the three types of glass previously described against the yeast I. orientalis.

[0051] The results obtained, expressed as the logarithm of the reduction in colony forming units (Table 3), show safe disinfection (log η > 4) for all glasses (glasses A, B, C and bioglass) with a CaO content exceeding 10% by weight . However, soda lime glass with a CaO content below 10% by weight did not show any biocidal activity.

[0052]

[0053] Table 3: Shows the log reduction in colony forming units of I. orientalis after 24 and 48 hours of biocide testing.

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Abstract

The present invention refers to the use of a powder of vitreous composition, characterised in that it has a minimum CaO content of 10% by weight, as biocide.

Description

technical field [0001] The invention relates to the use of a powder of a glassy composition as a biocide, characterized in that said powder has a minimum CaO content of 10% by weight. Background technique [0002] The use of glasses having copper, silver or zinc components with bactericidal and fungicidal activity can be discussed by Esteban-Tejeda L, Malpartida F, Esteban-Cubillo A, Pecharromán C and Moya JS, 2009, Nanotechnology 20 art.num.085103( 6pp); Esteban-Tejeda L, Malpartida F, Esteban-Cubillo A, Pecharromán C and Moya JS, 2009, Nanotechnology 20505701 doi: 10.1088 / 0957-4484 / 20 / 50 / 505701 (2009); Fang M, Chena JH, Xub XL , Yang PH and Hildebrand HF, 2006, International Journal of Antimicrobial Agents 27513-17; Rai M, Yadav A and Gade A, 2009, Biotechnology Advances 2776-83. These metal particles of copper, silver or zinc may be toxic and / or harmful to the environment. The same is the case with organic biocides such as triclosan, which is highly toxic and contaminat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N59/06A01N59/26
CPCC03C2204/02C03C12/00A01N59/06C03C3/091A01N25/10A01N25/34A01N59/26
Inventor J·莫亚科拉尔L·埃斯特班C·佩查罗曼F·马尔帕蒂达
Owner CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)
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