Preparation method of water-soluble isofraxidin mixed powder
A technology of isoxapidine and mixed powder, which is applied in the field of preparation of water-soluble isoxapidine mixed powder, can solve the problems that isoxapidine is difficult to dissolve in water, easily cause allergic reactions, and has poor water solubility, and achieves The effect of high utilization efficiency, good fluidity and low production cost for oral administration
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[0021] First configure 50mg / ml of isoxapyridine solution, and then slowly release the isoxapyridine solution into the homogenized mannitol aqueous solution whose rotation speed is 5000 rpm, the ratio of mannitol to water is 20mg / ml; at 20°C range mix. Homogenize the mixed liquid to make it into a uniform emulsion, remove the organic solvent by drying at 70°C, and obtain a powder with a uniform particle size of not more than 1000 microns by negative pressure freeze-drying.
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