Kit for detecting antinuclear antibody spectrum related to autoimmune diseases (AIDs)

An autoimmune disease and antinuclear antibody spectrum technology, applied in the field of disease diagnosis kits and autoimmune disease-related antinuclear antibody spectrum detection kits, can solve the problem that cannot be used as a basis for diagnosis, false positives, and different strip intervals and other problems, to achieve the effect of simple and reliable result judgment, uniform width and clean background
CN102937648BActive Publication Date: 2014-08-20SICHUAN XINCHENG BIOLOGICAL CO LTD
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Patents(China)
Current Assignee / Owner
SICHUAN XINCHENG BIOLOGICAL CO LTD
Publication Date
2014-08-20

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Abstract

The invention relates to a kit for detecting antinuclear antibody spectrum related to AIDs. The kit comprises a membrane strip, enzyme-labeled liquid, a substrate and concentrating and washing incubation liquid, wherein the membrane strip is composed of a carrier piece and an antigen band, a critical quality control band and a functional quality control line which are sequentially fixed on the carrier piece. The antigen band is composed of at least two of dsDNA, nucleosomes, SmD1, ribosome P0proteins, histones, U1snRNP, Ro / SS-A(52KD), Ro / SS-A(60KD), La / SS-B, Sc1-70, CENP-B, Jo-1, AMA-M2, PM-Sc1, PCNA, Mi-2 and Ku through independent marking to a nitrocellulose membrane or a nylon membrane. The kit is provided with the ingenious critical quality control band, one critical quality control band can play a role in interpreting two or even more detection bands (antigen bands), and result determination is simpler and more reliable.
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Description

technical field

[0001] The invention belongs to the field of biotechnology, and relates to a kit for diagnosing diseases, in particular to a kit for detecting antinuclear antibody spectrum related to autoimmune diseases. Background technique

[0002] Autoimmunity is the reaction of the body's immune system to self-antigens, producing autoantibodies and self-responsive T cells. Under normal physiological conditions, autoimmunity can promptly remove aging and dead self-cells and maintain the stability of the internal environment. In some pathological states, self-responsive T cells and autoantibodies that directly and indirectly destroy self-tissues may be produced, and cause lesions and dysfunction of corresponding organ tissues, which are called autoimmune diseases (AID) ). Common autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, multiple dermatitis / myositis, mixed connective tissue disease, hyperthyroidism, juvenile diabet...

Claims

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