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Novel method of applying oxymatrine to treating eczematous dermatitis

A technology of oxymatrine and dermatitis eczema, which is applied in the field of medicine, can solve the problems of large side effects and poor effect of dermatitis and eczema, and achieve the effect of low toxicity, treating both symptoms and root causes, and reversing the pathological mechanism

Inactive Publication Date: 2013-03-20
施惠娟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The purpose of the present invention is to solve the shortcomings of existing medicines and methods for treating dermatitis and eczema, such as poor effect and large side effects, and provide a new method of using oxymatrine to treat dermatitis and eczema

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] 1 Materials and methods

[0016] 1.1 Clinical data: 60 patients with generalized eczema were selected. The clinical diagnosis was consistent with acute eczema, subacute eczema or acute exacerbation of chronic eczema. They were 18-68 years old and had not received treatment within one month. They had no severe internal organs such as liver and kidney dysfunction. Diseases, no history of active tuberculosis, hypertension, diabetes, cataract, excluding pregnant and lactating women. The patients were randomly divided into two groups: a treatment group of 30 cases and a control group of 30 cases. There was no significant difference between the two groups in age, gender, disease duration, and disease severity (P>0.05).

[0017]1.2 Treatment method The treatment group was given intravenous infusion of oxymatrine injection (0.6g100ml) / d, and the antihistamine loratadine was taken orally; the control group was given loratadine orally. For those with obvious exudation, wet comp...

Embodiment 2

[0026] A total of 30 patients with eczema were selected and treated with oxymatrine (0.4g100ml) / d, 2 weeks as a course of treatment, and the curative effect was judged after the course of treatment was over. After statistical processing, the results showed that oxymatrine had significant curative effect in treating eczema, and no obvious adverse reactions were seen at the same time.

Embodiment 3

[0028] A total of 30 patients with eczema were selected and treated with oxymatrine capsules (300mg tid po). Two weeks was a course of treatment, and the curative effect was judged after the course of treatment was over. After statistical processing, the results showed that oxymatrine had significant curative effect in treating eczema, and no obvious adverse reactions were seen at the same time.

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Abstract

The invention provides a novel method of applying oxymatrine to treating eczematous dermatitis, belonging to the field of medicines. The method is characterized by 1. adopting intravenous drip of oxymatrine to treat eczematous dermatitis, 2. adopting intravenous drip of oxymatrine to treat eczematous dermatitis in combination with oral administration of antihistamines, 3. adopting oral administration of oxymatrine tablets or capsules to treat eczematous dermatitis and 4. applying oxymatrine ointments to the wounded parts to externally treat eczematous dermatitis. Compared with the existing medicines and methods for treating eczematous dermatitis, the novel method has the effects that unexpected curative effects can be obtained and the cure rate is above 75%. The new method is an innovative idea of holistic treatment for treating eczematous dermatitis and has great medical significance.

Description

[0001] technical field [0002] The invention belongs to the field of medicines, and in particular relates to a method for treating dermatitis and eczema with oxymatrine. Background technique [0003] As we all know, dermatitis and eczema skin diseases are common diseases in dermatology. The etiology and pathogenesis of dermatitis and eczema are not yet clear. The etiology is quite complicated, and most of them are caused by allergies. It is an allergic reaction caused by the interaction of various internal and external factors. But some dermatitis eczema has nothing to do with allergy. Changes in patient responsiveness often involve many factors, some of which are still unclear and need to be studied in the future. (1) Genetic factors: Certain types of eczema are closely related to genetics. Eczema patients often have certain allergic constitutions, and there is a history of allergic diseases in the family. Prone to allergic diseases such as contact dermatitis and drug re...

Claims

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Application Information

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IPC IPC(8): A61K31/4375A61P17/00
Inventor 施惠娟
Owner 施惠娟
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