Cattle fast-dissolving tablet with calcium hydroxymethionine as major ingredient and preparation process of tablet

Abstract

The invention belongs to the technical field of medicament preparation and especially relates to a cattle fast dissolving tablet with calcium hydroxymethionine as a major ingredient and a preparation process of the tablet. The fast dissolving tablet provided by the invention is characterized by comprising the following components by weight percent: 10-30% of calcium hydroxymethionine, 3-10% of disodium hydrogen phosphate, 31-10% of vitamin D, 20-30% of lactose, 20-40% of mannitol, 1-5% of sodium carboxymethyl starch and 5-10% of polyethylene glycol-6000. The preparation process comprises the steps of raw material treatment, mixing, preparing particles, drying, finishing, evenly mixing and tabletting. The fast dissolving tablet is used for preventing and treating calcium deficiency of the cattle, such as osteoporosis, cleidocranial dysplasia, and calcium supplement of pregnant cows and the cows of the lactation period; the functions of the organism parathyroid glands are activated by adjusting the calcium-phosphorus ratio so that calcium in the skeleton is used and calcium absorption is promoted, and parturient paresis caused by hypocalcemia after delivery of the cows is prevented and treated; and the fast dissolving tablet is convenient to use, high in dissolving speed, high in absorptivity, good in effect and good in stability.

Description

technical field [0001] The invention belongs to the field of medicine preparation, in particular to an instant tablet for cattle with hydroxymethionine calcium as the main ingredient and a preparation process thereof. [0002] Background technique [0002] The dairy industry is an important part of the animal husbandry industry. The development of the dairy industry is an important part of adjusting and optimizing the structure of the animal husbandry industry. It is an important measure to improve people's food structure, improve the quality of life, enhance people's physique, and promote the development of the national economy. However, at present, due to factors such as calcium deficiency, improper calcium and phosphorus, and calcium malabsorption, diseases such as growth retardation, osteoporosis, fetal dysplasia, and postpartum paralysis frequently occur in dairy cows. About 6% of dairy cows suffer from postpartum paralysis every year, and 66% of dairy cows suffer fro...

AI Technical Summary

Problems solved by technology

At present, there are many kinds of calcium supplements for dairy cows on the market, the main ingredients are calcium lactate, calcium carbonate, calcium gluconate, calcium citrate, etc. The common characteristics of these ingredients are low intestinal absorption rate, poor bioavailability, and large usage , therefore, the effect of calcium supplementation is not ideal

Dosage forms are ordinary tablets, oral liquids, etc.; the production process of oral liquids is cumbersome and costly; ordinary tablets have poor solubility, etc.