Origanum oil oral emulsion and preparation method thereof

An emulsifier and co-emulsifier technology, which is used in pharmaceutical formulations, emulsion delivery, and medical preparations containing active ingredients, etc., can solve the problems of inconvenient mixing, inconvenience for poultry drinking water, and application restrictions of oregano oil.

Inactive Publication Date: 2013-03-20
JIANGSU HFQ BIO TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Furthermore, the oregano oil premix material is inconvenient, and the oregano oil solution cannot be administered by drinking water as an oi

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0027] In the preparation method of oregano oil oral milk of the present invention, the preservative is dissolved in an appropriate amount of purified water or low-carbon fatty alcohol, and then dissolved in purified water together with an emulsifier and an emulsifier to form solution A; solution A is added to a colloid mill , adjust the rotation speed, stir and mix for 5-10 minutes; dissolve the antioxidant in the co-emulsifier, and then add it to the oregano oil to become solution B; slowly add solution B to solution A in the colloid mill, and emulsify for 10-60 minutes; Then filter and pack to obtain oregano oil oral milk.

[0028] In the present invention, solution B can be added to the colloid mill first, and then solution A can be added to solution B to emulsify in the colloid mill. The emulsification is accomplished through a tissue masher, milk homogenizer or high pressure shearing machine.

[0029] In the preparation method of oregano oil oral milk of the present inv...

Embodiment 1

[0033] Oregano oil 0.5%, emulsifier 0.5%, co-emulsifier 0.5%, preservative 0.01%, antioxidant 0.005%, purified water 98%; described emulsifier is Tween 80, and described co-emulsifier is propylene glycol, so The preservative is sodium benzoate, and the antioxidant is BHA.

[0034] Dissolve the preservative in an appropriate amount of purified water or low-carbon fatty alcohol, and then dissolve it in purified water together with emulsifier and co-emulsifier to form solution A;

[0035] Dissolve the antioxidant in the co-emulsifier, and then add it to the oregano oil to become solution B;

[0036] Add solution A to the colloid mill, adjust the rotation speed, and stir and mix for 5-10 minutes;

[0037] Slowly add solution B to solution A in the colloid mill, emulsify for 10-60 minutes; then filter and pack separately to obtain oregano oil oral milk.

Embodiment 2

[0039] Oregano oil 5%, emulsifier 15%, co-emulsifier 2%, preservative 0.1%, antioxidant 0.2%, purified water 78%; described emulsifier is Tween 80, and described co-emulsifier is dehydrated alcohol , the preservative is ethylparaben, and the antioxidant is BHA.

[0040] Dissolve the preservative in an appropriate amount of purified water or low-carbon fatty alcohol, and then dissolve it in purified water together with emulsifier and co-emulsifier to form solution A;

[0041]Dissolve the antioxidant in the co-emulsifier, and then add it to the oregano oil to become solution B;

[0042] Add solution B to the colloid mill, adjust the speed, and stir for 5-10 minutes;

[0043] Slowly add solution A to solution B in the colloid mill, emulsify for 10-60 minutes; then filter and pack separately to obtain oregano oil oral milk.

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Abstract

The invention aims to disclose an origanum oil oral emulsion and a preparation method of the origanum oil oral emulsion. The origanum oil oral emulsion comprises the following components according to weight percentage of 0.5-10% of origanum oil, 0.5-20% of an emulsifying agent, 0.5-10% of an auxiliary emulsifying agent, 0.01-1% of a preservative, 0.005-0.1% of an antioxidant, and the balance of purified water. Compared with the prior art, the disadvantages that the origanum oil is volatile and instable, has great thrill and is inconvenient to use can be effectively overcome; and the origanum oil oral emulsion has the characteristics of stability, high efficiency, greenness, safety, no drug resistance, no residues and convenience for use; and the aim of the invention is realized.

Description

technical field [0001] The invention relates to an oral milk and a preparation method thereof, in particular to a veterinary oregano oil oral milk and a preparation method thereof. Background technique [0002] Oregano oil is a yellow-red or brown-red essential oil extracted from the plant oregano, which has all the spicy and aromatic smell of thyme. Oregano is the whole herb of Origanum genus Lamiaceae, also known as Zhishencao, Nepeta and other local symbols. It has strong bactericidal and antibacterial properties of clearing away heat, removing dampness, dispelling heat, relieving exterior, and regulating qi. Function, the volatile oil extracted from oregano is the most pure traditional Chinese medicine additive with broad-spectrum antibacterial effect on 31 common enteritis-causing bacteria and Shigella flexneri. [0003] Oregano oil is one of the feed drug additives approved by the Ministry of Agriculture of my country. It is a safe, efficient, green, and non-incompati...

Claims

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Application Information

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IPC IPC(8): A61K36/53A61K9/107A61P31/04
Inventor 龙谭
Owner JIANGSU HFQ BIO TECH CO LTD
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