Method for preparing hemostatic sponge for dressing

Abstract

The invention provides a method for preparing hemostatic sponge for dressing. The method is characterized by comprising the following steps: (1) preparing a chitosan water solution; (2) injecting the prepared chitosan water solution into a mould; (3) freezing the chitosan water solution in the mould; (4) freeze-drying the frozen material; and (5) post-processing chitosan sponge. The method adopts the chitosan water solution as a raw material to prepare the hemostatic sponge for dressing. Through the processes such as freezing, freeze-drying, post-processing and the like, the produced sponge has a strong water absorbing capacity, namely good wet stability, is safer and more reliable, and has an obvious hemostatic effect, a strong absorption capacity and a wider range of application.

Description

technical field [0001] The invention provides a preparation method of a sponge, in particular a preparation method of a hemostatic sponge used for dressing. Background technique [0002] Trauma is a serious problem that endangers human health. According to the World Health Organization Trauma Treatment Guidelines, 16,000 people worldwide die from trauma every day, and medical expenses due to trauma are as high as 16% of all global medical expenditures, and 1 / 2 of the trauma patients 3 is death due to blood loss and multiple organ failure related to blood loss. If the bleeding can be stopped in time and effectively, it is very important to save the life of the wounded, stabilize the injury, and create conditions for follow-up treatment. Dressing, as a hemostatic material, refers to a protective covering on the wound, which can help control bleeding, prevent infection and absorb secretions. Hemostatic dressings are of great significance for timely hemostasis. At the same tim...

AI Technical Summary

Problems solved by technology

[0004] The hemostatic dressings on the market generally improve the hemostatic performance of the dressing by adding bioactive molecules, such as thrombin and fibrin, but the cost of such dressings is relatively high, and it is difficult to maintain the activity of such bioactive molecules

The existing chitosan hemostatic material is a chitosan derivative modified by polyacrylic acid. Approval of any related medical products containing polyacrylic acid, and a chitosan hemostatic sponge is a porous sponge with chitosan and gelatin as the main components. Dissolved, unable to exert coagulation performance