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Application of Shenkang injection in preparation of medicament for treating chronic renal failure complication or complication caused by dialysis

A technology of Shenkang injection and complications, applied in the field of Shenkang injection

Active Publication Date: 2013-04-24
XIAN SHIJISHENGKANG PHARMA IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, dialysis is still the main clinical treatment for CRF, but dialysis requires long-term maintenance treatment, so it will also cause a large number of complications, mainly pulmonary edema, peritonitis and other diseases

Method used

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  • Application of Shenkang injection in preparation of medicament for treating chronic renal failure complication or complication caused by dialysis
  • Application of Shenkang injection in preparation of medicament for treating chronic renal failure complication or complication caused by dialysis
  • Application of Shenkang injection in preparation of medicament for treating chronic renal failure complication or complication caused by dialysis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0079] Extract the Chinese herbal medicines in the Shenkang injection prescription with water respectively, then precipitate with ethanol, filter to obtain the filtrate, fine filter, adjust the pH value to 7.2, sterilize and pack into Chinese medicine dialysate.

Embodiment 2

[0081] The Shenkang injection prepared in Example 1 was directly mixed with conventional dialysate at a ratio of 0.1-1:1-10, and the pH value, osmotic pressure, conductivity, etc. were adjusted to meet the requirements of conventional dialysate to prepare a mixed dialysate.

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PUM

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Abstract

The invention provides application of Shenkang injection in preparation of a medicament for treating chronic renal failure complication or complication caused by peritoneal dialysis or blood dialysis. The Shenkang injection can be administrated in an intravenous infusion mode, or mixed with conventional dialysate and administrated or prepared into Chinese medicinal dialysate for dialytic administration. Animal experiments prove that the Shenkang injection can reduce the blood pressure, raises the N0 level, reduces the endothelin (ET) level, treats pulmonary edema, reduces the pulmonary coefficient and the pulmonary water content, improves renal anemia and treats peritoneal inflammation. The Shenkang injection has the advantages that the dialysis frequency is reduced, the occurrence of dialysis complication is reduced, the peritoneum is well protected, the dialysis effect is improved, the medical cost is reduced, further failure of the kidney is well delayed, the kidney is protetcted and the quality of life of a patient is improved.

Description

technical field [0001] The present invention relates to a new application and application method of Shenkang Injection, specifically, Shenkang Injection is directly mixed with conventional dialysate or prepared as a traditional Chinese medicine dialysate to prevent and treat chronic renal failure (CRF) complications And some complications caused by maintaining peritoneal dialysis or hemodialysis for a long time belong to the field of traditional Chinese medicine for treating urogenital diseases. Background technique [0002] Chronic renal failure (chronic renal failure for short), also known as chronic renal insufficiency (CRF), refers to chronic progressive renal parenchymal damage caused by various reasons, resulting in obvious atrophy of the kidneys, unable to maintain its basic functions, and appearing A syndrome composed of a series of symptoms and metabolic disorders. According to the International Society of Nephrology, the annual incidence of CRF is 98 to 198 per mi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/708A61K9/08A61P13/12A61P9/12A61P7/10A61P7/06A61P31/04
Inventor 曹凤君吕延英詹芳王光建赵兴王俊平
Owner XIAN SHIJISHENGKANG PHARMA IND
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