Application of magnolol in preparation of antitumor drug

An anti-tumor drug, the technology of magnolol, applied in the application field of magnolol in the preparation of anti-tumor drugs, can solve the problems of weak anti-autooxidation ability and no anti-oxidation activity, and achieve inhibition of proliferation and tumor suppression Obvious effect
CN103127039AInactive Publication Date: 2013-06-05FUDAN UNIV

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
FUDAN UNIV
Publication Date
2013-06-05
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention belongs to the chemical industry field and the medicine field, and relates to an application of magnolol in preparation of antitumor drugs. The invention provides the application of magnolol in preparation of antitumor drugs, and the tumor cells comprise liver cancer cells, and cervical cancer cells. The magnolol belongs to a natural product, has little toxic and side effect, high bioavailability, and stable properties, and has clinical application value. The micromolecular compound of the invention can be developed as a new antitumor drug or its auxiliary component, has obvious tumor suppression effect, is green and environment-friendly, and provides a new approach and means for treating and curing tumors.
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Description

technical field

[0001] The invention belongs to the fields of chemical industry and medicine, and relates to the application of magnolol in the preparation of antitumor drugs. Background technique

[0002] Magnolia officinale is brown to white fine powder Magnolia bark extract, the antibacterial active ingredient in the traditional Chinese medicine Magnolia officinalis, has a special, long-lasting muscle relaxation effect and strong antibacterial effect, and can inhibit platelet aggregation. It is mainly used clinically as an antibacterial and antifungal drug.

[0003] The basic parameters of magnolol are as follows:

[0004] 【English name】Magnolol

[0005] Alias】5',5-diallyl-2,2'-biphenyldiol

[0006] 【Chemical name】, 6', 7, 12-Tetramethoxy-2, 2'-dimethyl-1-beta-berbaman

[0007] 【Molecular formula and molecular weight】C18H1802, 266.32

[0008] 【CAS No.】528-43-8

[0009] [structural formula]

[0010]

[0011] The application of supercritical CO by Li Jiaxiao et a...

Claims

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