19 results about "Lactobacillus acidipiscis" patented technology

The present invention discloses an anti-inflammatory Lactobacillus acidophilus composition for regulating immune responses, belonging to the fields of microbial technology and biomedicine. The composition comprises live lyophilized powders of Lactobacillus acidophilus, Lactobacillus plantarum, and Bifidobacterium longum, together with homologous postbiotic lyophilized powders of the same strains. By combining functionally complementary probiotics with their homologous postbiotics, a full-chain anti-inflammatory system is constructed, covering immune regulation, inflammation suppression, and intestinal barrier repair. The live bacteria enable long-term colonization and microecological regulation, while the postbiotics act rapidly, producing a synergistic effect. The composition is prepared solely from strain-derived fermentation products without exogenous additives, ensuring safety and purity, and provides a stable and efficient solution for inflammation relief and immune function optimization.

This invention belongs to the field of food fermentation technology, and specifically relates to a compound probiotic agent and its application in the preparation of fermented soy milk. This invention provides a compound probiotic agent composed of *Lactobacillus fermentum* NCPS LF01, *Pediococcus pentosaceus* NCPS PPE01, and *Lactobacillus acidophilus* NCPS LA01 in a volume ratio of 1-2:1:1, and applies this compound probiotic agent to the preparation of soy products, especially fermented soy milk. The beneficial effects of this invention are that fermented soy milk prepared using this compound probiotic agent has a rich flavor, and the total flavonoid and total phenolic content, as well as the in vitro DPPH free radical scavenging rate, are significantly superior to those of ordinary commercially available strains or other strains. In summary, this compound probiotic agent can effectively improve the retention level of active ingredients and antioxidant capacity of fermented soy milk, and has outstanding application value.

The application provides a compound microbial inoculum for preparing pickled Chinese cabbage through fermentation of bean water and a fermentation method, and belongs to the technical field of fermented food technology.The compound microbial inoculum for preparing pickled Chinese cabbage through fermentation of bean water comprises the following bacterial species in percentage by mass: 40-60% of Lactobacillus plantarum, 20-35% of Lactobacillus acidophilus, 10-25% of Saccharomyces cerevisiae and 5-15% of Bacillus acidophilus.The pre-processed bean water is used as a fermentation substrate, and the compound microbial inoculum is inoculated to prepare pickled Chinese cabbage through fermentation, so that the fermentation period is shortened, the fermentation quality of the pickled Chinese cabbage is improved, the safety of the pickled Chinese cabbage is ensured, the pickled Chinese cabbage is endowed with special bean aroma, and the resource utilization of the bean water is realized.

The application discloses a preparation method and application of a composite strain of a sugar-controlling probiotic, and belongs to the technical field of microorganisms. The method comprises the steps of strain stock solution preparation, anaerobic culture, pH value determination and regulation, and composite strain proportioning. Through a dynamic shunting mechanism with pH value 4.3 as a threshold, the culture solution lower than the value is subjected to re-acidification treatment, and the culture solution higher than the value is subjected to differential dilution and coating operation. Finally, Lactobacillus gasseri, Streptococcus thermophilus, Lactobacillus bulgaricus, Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus paracasei, Bifidobacterium breve, Bifidobacterium lactis and Bifidobacterium longum are mixed at a preset ratio, and a sustained-release agent is added for storage. The method can significantly improve the screening efficiency of target probiotics, the stability of the composite preparation and the blood glucose regulation effect, and can be widely applied to the development of sugar-controlling probiotic products.

This invention discloses a kidney-tonifying and liver-nourishing compound probiotic Cistanche fermented drink and its preparation method, comprising the following steps: mixing and sterilizing Cistanche deserticola, Poria cocos, malt, functional components, and natural selenium-strontium mineral water to obtain a fermentation substrate; activating *Lactobacillus casei*, *Lactobacillus acidophilus*, *Lactobacillus rhamnosus*, and *Lactobacillus plantarum* strains respectively, centrifuging and freeze-drying, and then mixing them to obtain a compound probiotic powder; culturing the compound probiotic powder in MRS medium to obtain a compound probiotic liquid; inoculating the compound probiotic liquid into the fermentation substrate for fermentation, sterilizing, and obtaining the kidney-tonifying and liver-nourishing compound probiotic Cistanche deserticola fermented drink. This invention, through the innovative integrated formulation technology of combining Cistanche deserticola, malt, and Poria cocos as medicinal and edible ingredients, multifunctional factor compounding, and compound probiotic fermentation, prepares a kidney-tonifying probiotic Cistanche deserticola fermented drink with high active ingredients, clear efficacy, and excellent flavor.

The application discloses a cat oral cavity nursing probiotic composition and application thereof, and the probiotic composition comprises animal bifidobacterium and lactic acid bacteria, wherein the lactic acid bacteria is any one or a combination of multiple of salivarius, lactobacillus casei, enterococcus faecalis, lactobacillus rhamnosus, lactobacillus plantarum, lactobacillus acidophilus and lactobacillus reuteri; compared with single probiotic, the probiotic composition has better effect on oral cavity odor removal, can effectively improve cat oral cavity source halitosis, and can also reduce dental plaque formation, relieve gingivitis and dental caries, and can be applied to preparation of a cat oral cavity odor cleaner, and has good application prospect.

A probiotic composition for treating or preventing metabolic dysfunction-associated steatotic liver disease-associated hepatocellular carcinoma(MASLD-HCC) or colorectal cancer, comprises one or more microbiota selected from a group consisting of Lactobacillus helveticus, Lactobacillus plantarum, Lactobacillus rhamnosus GG, Lactobacillus paracasei, Lactobacillus acidophilus, Bifidobacterium breve, Bifidobacterium animalis subsp. Lactis, Streptococcus thermophilus or any combination thereof. The probiotic composition demonstrates improved therapeutic effects when combined with low-dose Sorafenib for MASLD-HCC and outperforms 5-Fluorouracil in colorectal cancer models.

An oat preparation, an oat product comprising the oat preparation, a preparation method therefor and the use thereof. The oat preparation is obtained by fermenting a fermentation broth; the fermentation broth comprises a fermentation substrate and a starter culture; the fermentation substrate mainly consists of hydrolyzed oat bran; the starter culture comprises lactobacillus reuteri, lactobacillus plantarum, lactobacillus acidophilus, bifidobacterium lactis and lactobacillus rhamnosus, and comprises streptococcus salivarius subsp. thermophilus and lactobacillus delbrueckii subsp. bulgaricus.

The application discloses lactobacillus degrading hippophae rhamnoides malic acid and application thereof in preparation of hippophae rhamnoides juice, wherein one strain is classified and named as lactobacillus acidophilus (Lactobacillus acidophilus) Lactobacillus acidipiscis ) with a preservation number of CGMCC No. 37351, and one strain is classified and named as lactobacillus plantarum (Lactobacillus plantarum) Lactobacillus plantarum ) with a preservation number of CGMCC No. 37352. Fresh hippophae rhamnoides juice is mixed with sterile water according to a proportion, pasteurized after sugar degree is adjusted, cooled to room temperature, and pretreated; the lactobacillus is inoculated into the pretreated hippophae rhamnoides juice after being cultured to a logarithmic growth phase, and anaerobically cultured at 35±1 DEG C for 90-96 h. The lactobacillus screened in the application has a remarkable degradation effect on hippophae rhamnoides malic acid, can efficiently degrade hippophae rhamnoides malic acid, and meanwhile retains nutrition function and natural flavor, and can be used for preparation of hippophae rhamnoides juice.

The present disclosure relates to the field of microbial therapy, and specifically to a product for preventing and / or treating obesity and a metabolic syndrome. The product includes a Lactobacillus acidophilus strain JYLA-126 and a coating solution thereof. A bacterial solution of the L. acidophilus strain JYLA-126 is coated with a bacterial coating solution to better transport the bacterial solution to the intestinal tract to exert therapeutic effects. The L. acidophilus strain JYLA-126 coating solution is used for intragastric treatment of obesity mice induced by high-fat diet. Various indicators show that the L. acidophilus strain JYLA-126 coating solution may effectively regulate intestinal microflora and maintain intestinal health. The coating solution improves liver glucose metabolism, reduces liver oxidative stress, improves liver lipid metabolism, and alleviates a liver inflammation level. This coating solution improves white adipose accumulation and promotes brown adipose thermogenesis, thereby achieving effective treatment of obesity and metabolic syndrome in mice.

The application discloses a preparation method of lactic acid bacteria fermented foxtail chub jelly. The application uses foxtail chub natural gum to replace artificial thickening agent, uses cane sugar and milk to prepare a mixed substrate, uses Lactobacillus bulgaricus, Lactobacillus acidophilus and Streptococcus thermophilus to prepare a lactic acid bacteria preparation, and performs combined fermentation to produce organic acid to replace citric acid to promote coagulation, without adding preservatives, so that the functional jelly with pure naturalness, high nutrition and excellent flavor is prepared.

This invention discloses a biological agent suitable for squab growth, its preparation method, and its application, belonging to the field of feed technology. It comprises the following components by weight: 8-40 parts of microbial agent, 1-10 parts of additive, 1-10 parts of antioxidant, 0.5-5 parts of peptidoglycan, and 40-60 parts of montmorillonite. The microbial agent includes *Bifidobacterium animalis*, *Lactobacillus acidophilus*, *Lactobacillus paracasei*, and *Lactobacillus reuteri*. The additive includes at least one of yeast β-glucan and astragalus polysaccharide. The biological agent for squab growth of this application uses montmorillonite as a base material. Under the combined action of the microbial agent, additive, antioxidant, and peptidoglycan, it can regulate the intestinal health of breeding pigeons, improve their immunity, and increase immune factors in pigeon milk. This can improve the growth performance of squabs, reduce the culling rate of both breeding and squabs, thereby increasing economic benefits and showing broad application prospects.

The application discloses a red crawfish food-enticing fermented feed and a preparation method thereof, and belongs to the technical field of feed fermentation and food-enticing. The red crawfish food-enticing fermented feed is prepared by using a complex bacteria liquid system of Hansenula, Saccharomyces cerevisiae, Lactobacillus plantarum and Lactobacillus acidophilus, and a large amount of high-activity esters and acid-smelling food-enticing substances are generated through a double mechanism of "bacteria liquid culture first round ester production + continuous ester production in puffed material", and the food-enticing effect is further improved after synergistic action with conventional food-enticing agents. The red crawfish food-enticing fermented feed provided by the application can significantly shorten the feeding response time of red crawfish, improve the feeding rate, especially in the low-temperature environment of 8-20 DEG C in autumn, winter and early spring, and the effect is outstanding. Meanwhile, the red crawfish food-enticing fermented feed can significantly improve the weight gain rate, survival rate and intestinal digestive enzyme activity of red crawfish, reduce the ammonia nitrogen and nitrite content of the aquaculture water, solve the problems of low feeding of red crawfish, low feed utilization rate and water pollution in the low-temperature period, provide a feed solution with stronger food-enticing effect and green high efficiency, and has a wide application prospect.

The application provides a probiotic composition capable of promoting proliferation of intestinal flora, and a preparation method and application thereof, and relates to the technical field of microorganisms. The probiotic composition comprises the following raw materials: probiotics and prebiotics; the probiotics are a mixture of lactobacillus crispatus, lactobacillus acidophilus and animal bifidobacterium with a mass ratio of (0.1-2):(2-4):(5-7); and the prebiotics are a mixture of xylo-oligosaccharide, oat beta-glucan, arabinoxylan and 2'-fucosyllactose with a mass ratio of (3-5):(1-2):(3-4):(0.1-1). The application significantly promotes proliferation of beneficial flora in the intestines through specific probiotics and specific prebiotics, and interaction between components.

This invention provides a children's eye-protecting compound fermented beverage and its preparation method, comprising the following steps: Adding wolfberry, Chinese yam, pitted red dates, Hangzhou white chrysanthemum, and honeysuckle to purified water, extracting, filtering to remove residue, and obtaining a medicinal and edible extract; adding blueberry concentrate, black wolfberry extract, mulberry concentrate, raspberry concentrate, crystalline fructose, fructooligosaccharides, galactooligosaccharides, malic acid, and eye-protecting functional ingredients sequentially to the extract, stirring evenly to obtain a liquid; sterilizing and cooling the liquid; inoculating the sterilized and cooled liquid with *Lactobacillus plantarum*, *Lactobacillus rhamnosus*, and *Lactobacillus acidophilus*, and fermenting at a constant temperature of 37°C in a sealed container for 24–36 hours until the pH stabilizes at 3.5–3.7, then terminating the fermentation. Homogenizing and bottling. This invention, using the above-mentioned children's eye-protecting compound fermented beverage and its preparation method, has a mild formula, comprehensive eye-protecting ingredients, and undergoes deep fermentation with probiotics, making it suitable for children over 3 years old.

The application discloses application of a probiotic compound preparation containing Bifidobacterium longum exopolysaccharide in prevention and treatment of colitis. In the application, the potential of the Bifidobacterium longum exopolysaccharide in preparation of prevention and / or treatment of ulcerative colitis is first proposed, and it is found that the Bifidobacterium longum exopolysaccharide can produce a strong synergistic effect in combination with Lactobacillus acidophilus, and can produce an effect of inhibiting intestinal inflammation of a DSS-induced colitis model mouse.

A composition for treating insomnia, comprising a probiotic complex and traditional Chinese medicine components. The probiotic complex comprises Lactobacillus plantarum, Bifidobacterium lactis, Lactobacillus crispatus, Lactobacillus acidophilus, Lactobacillus rhamnosus, Bifidobacterium bifidum, Lactobacillus reuteri, Lactobacillus casei, Lactobacillus delbrueckii subsp. bulgaricus, Lactobacillus fermentum, Lactobacillus gasseri, Lactococcus lactis, Bifidobacterium longum, Lactobacillus salivarius, Bifidobacterium breve, Streptococcus thermophilus, Lactobacillus paracasei and Lactobacillus helveticus. The traditional Chinese medicine components are semen ziziphi spinosae, bulbus lilii, poria, semen nelumbinis and mori fructus. The composition may further comprise prebiotics selected from L-arabinose, β-glucan, inulin, erythritol, lactitol, vitamin C and γ-aminobutyric acid. The composition can be used for preparing pharmaceutical or food formulations, such as solid beverages, chewable tablets or oral lozenges. Clinical observation shows that the composition has the effect of relieving insomnia.

The present invention provides an oat product obtained by fermenting a fermentation solution comprising a fermentation substrate consisting essentially of hydrolyzed oat bran and a fermenting agent comprising Lactobacillus reuteri, Lactobacillus plantarum, Lactobacillus acidophilus, Bifidobacterium lactis and Lactobacillus rhamnosus and comprising Streptococcus salivarius subsp. thermophilus and Lactobacillus delbrueckii subsp. bulgaricus. The present invention also provides an oat product comprising the oat product and methods of making and uses of the oat product.

The application discloses a lactic acid bacteria CCFM1460 which can produce multiple bioactive substances to promote skin barrier repair and a postbiotic of the lactic acid bacteria CCFM1460, and belongs to the technical field of microorganisms and medical technology.The lactic acid bacteria CCFM1460 provided in the application can produce 3,4-dihydroxyphenyl glycol, N-tetradecyl diethanolamine and 3-phenyl lactic acid through fermentation.The postbiotic of the lactic acid bacteria CCFM1460 has a good skin barrier repair effect.The cell lysate and fermentation supernatant of the lactic acid bacteria CCFM1460 can improve the cell activity of damaged keratinocytes and the expression levels of FLG, IVL and LOR genes, and the cell lysate of the CCFM1460 can improve the expression levels of ZO-1, OCCLUDIN and CLDN genes.Therefore, the lactic acid bacteria has a great application prospect in the preparation of external use or oral medicine or cosmetics for repairing skin barrier.