Traditional Chinese medicine composition used for treating chronic liver diseases
A technology for chronic liver disease and composition, applied in the field of traditional Chinese medicine compositions for the treatment of chronic liver disease, can solve problems such as no literature report found
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Embodiment 1
[0017] Using CCl 4 The induced mouse liver fibrosis model confirmed that the traditional Chinese medicine compound can significantly inhibit the progression of liver fibrosis and the formation of liver cirrhosis.
[0018] 1. Materials and methods:
[0019] 1.1 Animals
[0020] Forty clean-grade male C57BL / 6 mice, 8 weeks old, weighing 20±3g, were purchased from the Shanghai Experimental Animal Center of the Chinese Academy of Sciences. Raised, modeled and observed in the Experimental Animal Center of Shanghai University of Traditional Chinese Medicine, free to eat and drink.
[0021] 1.2 Main reagents and equipment
[0022] Carbon tetrachloride (CCl 4 ) was purchased from Sinopharm Group, the standard product of hydroxyproline (Hyp) was purchased from Tokyo Chemical Industry Co., Ltd.; the Olympus IX70 optical microscope was purchased from Olympus Company.
[0023] 1.3 medicine (using Chinese medicine composition of the present invention)
[0024] Sanleng 6-18g, Curcuma ...
Embodiment 2
[0050] The preparation of embodiment 2 tablet
[0051] Weigh the following raw materials: 6g trigonum, 6g curcuma, and 9g turtle shell, make coarse powder, soak in 15 times the amount of water each time for 0.5 hour, heat and reflux for extraction twice, concentrate the filtrate to an extract, and dry infusion after vacuum drying paste; after adding appropriate amount of excipients, tablets are prepared. Each tablet contains 90 mg of the traditional Chinese medicine composition. Usage: 5 tablets each time, 3 times a day, 7 days a week, 12 weeks as a course of treatment.
Embodiment 3
[0052] The preparation of embodiment 3 granules
[0053] Weigh the following raw materials: 18g trigonum, 18g curcuma, and 30g turtle shell, and make coarse powder, soak in 15 times the amount of water for 0.5 hour each time, heat and reflux for extraction twice, concentrate the filtrate to extract, and dry infusion after vacuum drying paste; after adding appropriate amount of excipients, granules are obtained. Each bag of granules contains 175 mg of the traditional Chinese medicine composition. Usage: 3 bags each time, 3 times a day, 7 days a week, 12 weeks as a course of treatment.
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