Use of alpha-ketoglutaric acid

The technology of ketoglutaric acid and grass carp is applied in the application field of alpha-ketoglutaric acid, which can solve the problems of poor resistance to ammonia nitrogen stress, low immunity, slow growth of grass carp, etc., achieve strong disease resistance and promote grass carp Growth, improve feed conversion efficiency

Active Publication Date: 2014-05-07
HUNAN AGRICULTURAL UNIV
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

[0008] The technical problem to be solved by the present invention is to provide a use of α-ketoglutarate for grass carp with slow growth, low immunity and poor ability to resist ammonia nitrogen stress in the prior art. Added as a feed additive to grass carp feed, it can promote the growth of grass carp, improve the feed conversion rate, and improve the ability of grass carp to resist ammonia nitrogen stress

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  • Use of alpha-ketoglutaric acid
  • Use of alpha-ketoglutaric acid

Examples

Experimental program
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Effect test

Embodiment 1

[0015] Example 1: Effects of α-ketoglutarate on growth performance and blood biochemical indicators of grass carp

[0016] Test materials: α-ketoglutaric acid was purchased from Shanghai Haiqu Chemical Co., Ltd., a white fine crystalline powder with a purity of 98.5%.

[0017] Test site: Hunan Agricultural University aquaculture base.

[0018] Test feed and grouping: select 180 healthy grass carp with an average body weight of 35.66 grams, and randomly divide them into two treatment groups, namely the control group and the α-ketoglutaric acid addition group (the feed group of the present invention), and each treatment has 3 repetitions , each repeated 30 tails, fed the basal ration and the feed ration of the present invention respectively. Grass carp basal diet is formulated according to the nutritional standard of grass carp compound feed (SC / T 1024-1997), and its composition and nutritional level are shown in Table 1:

[0019] Table 1 Composition and nutritional level of b...

Embodiment 2

[0030] Example 2: Effect of α-ketoglutarate on grass carp ammonia nitrogen stress

[0031] Test material, place, test feed and grouping, feeding test method are uniformly described in embodiment 1. After the feeding experiment (60 days), 15 fish with close to average body weight were randomly selected from each treatment, and put into 4 CL modulated the total ammonia nitrogen concentration of 20 mg / L in water for acute ammonia nitrogen stress test, carefully observed and recorded the behavioral response and death of fish.

[0032] The results of the acute ammonia nitrogen stress test showed that grass carp fed the basal diet group were extremely restless in the ammonia nitrogen stress test. As the exposure time prolongs, the swimming slows down and is accompanied by sideways or rollover movements, the breathing speed slows down, the operculum opening and closing slowly, and hides or swims into the bottom after being frightened. After 3 hours, some fish began to stiffen and d...

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Abstract

The invention discloses a use of alpha-ketoglutaric acid. The alpha-ketoglutaric acid can be used as immune regulating / promoting agent for grass carp and anti-ammonia-nitrogen stress agent additive for the grass carp in the form of additive to be added into grass carp feed, so that the grass carp growth can be promoted and the immune function and anti-ammonia-nitrogen stress capacity of the grass carp can be improved, and therefore, problems that the grass carp feed conversion rate is low, and the anti-ammonia-nitrogen stress capacity of the grass carp is poor can be solved.

Description

technical field [0001] The invention relates to the application of α-ketoglutarate in the form of a feed additive as an immune regulator / promoter and an anti-ammonia stress agent in grass carp feed. Background technique [0002] The modern high-density intensive farming model increases the input of nitrogen sources in the aquaculture water body, resulting in high ammonia nitrogen content in the water body, resulting in reduced food intake for aquatic animals, increased demand for energy, decreased growth rate, and decreased immunity, which seriously hinders aquaculture. healthy development of the industry. For example, grass carp, one of the four major domestic carps in my country, in recent years, due to the continuous increase in breeding density, the content of harmful substances mainly ammonia nitrogen in the water body exceeds the standard, resulting in slow growth, frequent occurrence of diseases and difficult treatment, greatly reducing the survival rate. and output, ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23K1/16A23K1/18
Inventor 赵玉蓉王红权金柏涛唐德约梁健
Owner HUNAN AGRICULTURAL UNIV
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