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Tension headache treatment preparation

A therapeutic agent and tension technology, applied in the field of tension headache therapeutic agents, can solve the problems of insignificant improvement of symptoms, short headache attack frequency and duration, easy recurrence of patients' symptoms, etc., and achieve alleviating hyperalgesia and no drug side effects , Improve the effect of headache

Inactive Publication Date: 2013-11-27
童绥君
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0018] 5. Cannot be attributed to other diseases: that is, to exclude secondary headache causes such as cerebral hemorrhage and subarachnoid hemorrhage, as well as migraine and cluster headaches.
Through the research of multiple groups of clinical medical records, the above-mentioned methods for treating tension headaches currently used clinically can improve the headache of patients, reduce the frequency and duration of headache attacks, have short curative effect, and the symptoms are not improved obviously, and the symptoms of patients are easy to repeat.

Method used

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  • Tension headache treatment preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Outpatient Zhang XX, female, 65 years old, came to our hospital with the main complaint of "repeated headache for more than 2 years". History of present illness: headache due to no obvious inducement more than 2 years ago, manifested as paroxysmal dull pain in the whole head, the location is not fixed, each time lasts 1-2 hours, about 2-3 times a month, after exercise No aggravation, slight improvement after rest, accompanied by poor sleep, no nausea, vomiting, fever, chills, fear of sound, photophobia, numbness of limbs, slurred speech, difficulty swallowing, drinking water cough, tinnitus, hearing loss Declining, went to other hospitals for many times, and gave symptomatic treatment (specifically unknown). Symptoms did not improve, and headaches recurred, so he was referred to our hospital. Physical examination: T36.6°C, P77 beats / min, R19 beats / min, BP121 / 82mmHg, clear mind, normal spirit, clear speech, correct answer, good response, good memory and comprehension, do...

Embodiment 2

[0039] Outpatient Shi XX, female, 64 years old, went to the outpatient department of our hospital with the main complaint of "repeated headache for more than 5 years". History of present illness: headache due to no obvious inducement more than 5 years ago, manifested as bilateral occipital, temporal, and overhead migratory paroxysmal dull pain, lasting for several hours each time, about 5 times a month, active No aggravation after rest, slight improvement after rest, accompanied by palpitations, chest tightness, poor mood, no fever, chills, nausea, vomiting, fear of sound, photophobia, numbness of limbs, slurred speech, difficulty swallowing, drinking water and coughing , no tinnitus, hearing loss, multiple visits to other hospitals, given symptomatic treatment (specifically unknown), no improvement in symptoms, repeated headaches, referral to our hospital. Physical examination: T36.8°C, P79 beats / min, R20 beats / min, BP121 / 88mmHg, clear mind, normal spirit, clear speech, corre...

Embodiment 3

[0041]Outpatient Lin XX, male, 43 years old, came to the outpatient department of our hospital with the main complaint of "repeated headache for half a year". History of present illness: headache due to no obvious inducement more than half a year ago, manifested as bilateral occipital, paroxysmal dull pain on the top of the head, the location is not fixed, each time lasts for half an hour to 1 hour, about 1-2 times a month , No aggravation after activities, slight improvement after rest, accompanied by palpitations, poor sleep, no fever, chills, no nausea, vomiting, no fear of sound, photophobia, no weakness and numbness of limbs, no slurred speech, difficulty swallowing, drinking water and coughing , went to other hospitals for many times, and gave symptomatic treatment (specifically unknown). Symptoms did not improve, and headaches recurred, so he was referred to our hospital. Physical examination: T36.3°C, P69 beats / min, R20 beats / min, BP116 / 78mmHg, clear mind, normal spiri...

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Abstract

The invention discloses a tension headache treatment preparation. The preparation is mainly prepared from the following components: seroxat, deanxit and clonazepam. The target of the treatment agent acts on a plurality of etiological factors of tension headache, and the treatment agent has remarkable effects of comprehensively regulating neurotransmitter of the central nervous system, relieving hyperpathia and the like, has obvious effects of relieving headache and reducing the headache attack frequency and duration, and does not have remarkable medical side effect.

Description

technical field [0001] The present invention relates to a therapeutic agent for tension headache. Background technique [0002] Tension headache is a compression or compression headache of the whole head, accounting for about 50%-60% of headache patients. It is the most common clinical chronic headache and brings endless pain to patients. [0003] 1. The etiology and pathogenesis of tension headache [0004] (1) Central pain mechanism [0005] It is an important mechanism that causes tension headache. The abnormal function of neurotransmitters in the central nervous system may cause chronic or intermittent dysfunction of various neurotransmitters, which may cause functional or structural abnormalities in the dorsal horn of the spinal cord, trigeminal nucleus, thalamus, and cortex. , the pain threshold to tactile, electrical, and thermal stimuli is significantly reduced, and hyperalgesia is prone to occur. Neuroimaging studies have confirmed that there is a reduction in th...

Claims

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Application Information

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IPC IPC(8): A61K31/5513A61P25/04A61P25/22A61P25/20A61K31/4525A61K31/496A61K31/135
Inventor 童绥君马琪林毕敏李剑鹏江斌
Owner 童绥君
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