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Application of traditional Chinese medicine composition in preparation of medicines for preparing diabetic ketoacidosis complicated with leukemoid reaction

A leukemia-like and composition technology, applied in the field of traditional Chinese medicine compositions, can solve problems such as the application of unrecorded pharmaceutical compositions

Active Publication Date: 2014-01-15
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The patent does not record the application of the pharmaceutical composition in the preparation of drugs for the treatment of diabetic ketoacidosis complicated with leukemia-like reactions

Method used

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  • Application of traditional Chinese medicine composition in preparation of medicines for preparing diabetic ketoacidosis complicated with leukemoid reaction
  • Application of traditional Chinese medicine composition in preparation of medicines for preparing diabetic ketoacidosis complicated with leukemoid reaction

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] The raw material formula is :

[0058] Ginseng 102 g, Polygonatum 136 g, Atractylodes 68 g, Sophora flavescens 56 g, Poria cocos 83 g, Ophiopogon japonicus 136 g, Polygonum multiflorum 83 g, Rehmannia glutinosa 102 g, Cornus officinalis 136 g, Coptidis 56 g, Perrin 56 g, Lychee core 136 g g, Epimedium 56 g, Anemarrhena 68 g, Salvia 89 g, Pueraria 136 g, Digupi 83 g;

[0059] The preparation method is :

[0060] a. Weigh Chinese medicinal materials according to the prescription amount, cleanly select and break;

[0061] b. Add 6 times the amount of water to Peilan and Cangzhu to extract the volatile oil. The oil extraction time is 5 hours. The volatile oil is collected in another device, and the aqueous solution is filtered for later use, and the residue is discarded;

[0062] c. Cornus officinalis is impregnated with 7 times the amount of 75% ethanol for 24 hours, then percolated, the percolated liquid is collected, the ethanol is recovered, concentrated into a th...

Embodiment 2

[0068] The raw material drug formula is:

[0069] Ginseng 42g, Polygonatum 200g, Atractylodes 30g, Sophora flavescens 60g, Poria cocos 35g, Ophiopogon japonicus 200g, Polygonum multiflorum 35g, Rehmannia glutinosa 120g, Cornus officinalis 50g, Coptis 60g, Perrin 30g, Lychee core 150g g, Epimedium 30 g, Anemarrhena 100 g, Salvia miltiorrhiza 35 g, Pueraria 200 g, Digupi 30 g;

[0070] The preparation method is :

[0071] a. Weigh Chinese herbal medicines according to the prescription amount, cleanly select and break them;

[0072] b. Add 5 times the amount of water to Peilan and Cangzhu to extract the volatile oil. The oil extraction time is 3 hours. The volatile oil is collected in another device, and the aqueous solution is filtered for later use, and the residue is discarded;

[0073] c. After impregnating Cornus officinalis with 5 times the amount of 50% ethanol for 12 hours, perform percolation, collect the percolation liquid, recover ethanol, concentrate it into a thi...

Embodiment 3

[0079] Ginseng 160g, Polygonatum 50g, Atractylodes 100g, Sophora flavescens 20g, Poria cocos 100g, Ophiopogon japonicus 50g, Polygonum multiflorum 100g, Rehmannia glutinosa 50g, Cornus officinalis 200g, Coptidis 20g, Perrin 60g, Lychee core 75g g, Epimedium 60 g, Anemarrhena 30 g, Salvia miltiorrhiza 120 g, Pueraria 50 g, Digupi 100 g;

[0080] The preparation method is :

[0081] a. Weigh Chinese herbal medicines according to the prescription amount, cleanly select and break them;

[0082] b. Add 9 times the amount of water to Peilan and Cangzhu to extract the volatile oil. The oil extraction time is 6 hours. The volatile oil is collected in another device, and the aqueous solution is filtered for later use, and the residue is discarded;

[0083] c. Cornus officinalis is impregnated with 9 times the amount of 90% ethanol for 48 hours, then percolated, the percolated liquid is collected, the ethanol is recovered, and concentrated into a thick paste with a relative density o...

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Abstract

The invention discloses an application of a traditional Chinese medicine composition in the preparation of medicines for preparing diabetic ketoacidosis complicated with leukemoid reaction. The traditional Chinese medicine composition comprises herbal medicines such as ginseng, rhizoma polygonati, rhizoma atractylodis, radix sophorae flavescentis, poria cocos, dwarf lilyturf tuber, prepared fleeceflower root, rehmannia root, dogwood, coptidis rhizoma and fortune eupatorium herb. The traditional Chinese medicine composition is mainly used for tonifying qi and yin, strengthening spleen and transferring body fluid, and has the effects of clearing away heat, eliminating dampness and promoting blood circulation to remove meridian obstruction. After the traditional Chinese medicine composition is taken, the dosage of insulin used by patients is gradually reduced, the blood glucose control is normal and stable, the time of urine acetone bodies turning to negative is obviously shortened, and the state of illness can be controlled as soon as possible.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition, in particular to an application of a traditional Chinese medicine composition in the preparation of a medicine for treating diabetic ketoacidosis complicated with leukemia-like reaction. Background technique [0002] Diabetic ketoacidosis (DKA) is due to insufficient insulin and inappropriate increase in blood sugar-raising hormones, causing metabolic disorders of sugar, fat and protein, as well as water, electrolyte and acid-base balance disorders, resulting in high blood sugar, high blood ketone and metabolic disorders. Acidosis is the main clinical syndrome. It is an acute complication of diabetes and can lead to coma in severe cases. In infection and various stress states, insulin deficiency and insulin resistance are more serious, and resistance-regulating hormones increase, which further aggravates metabolic disorders. Elevated blood sugar, complicated by ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P3/12A61P3/10
Inventor 魏聪常丽萍安军永王永王猛秦拢王超
Owner HEBEI YILING MEDICINE INST
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