Application of goose not herbivorous CO2 supercritical extract in preparing medicine or food with anti-influenza virus effect

A technology of supercritical extract and anti-influenza virus, which is applied in the field of medicine, can solve the problems that do not involve the anti-influenza virus of goose herbivore extract, and achieve good medical application value, strong anti-virus effect, and good anti-influenza The effect of the virus

Active Publication Date: 2016-01-20
JINAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, among the many research results, there is no report on whether the goose herbivore extract has the effect of anti-influenza virus

Method used

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  • Application of goose not herbivorous CO2 supercritical extract in preparing medicine or food with anti-influenza virus effect

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] 300g goose does not eat grass (collected from Guangdong, identified by Mai Zhenqiu, a senior engineer of Guangzhou Medicinal Materials Company, as a plant of Compositae Centipeda minima (L.)A.Br.et.Aschers, the following examples are the same) dried whole grass or flowered whole grass (the following examples are the same) pulverized, cross 60 mesh sieves, place in CO 2 In the supercritical extraction apparatus, the extraction pressure was 25 MPa, the extraction temperature was 38°C, the flow rate was 20 liters / hour, and the extraction time was 2 hours, the CO 2 Supercritical extract 20.3g.

Embodiment 2

[0031] Grind 300g of dried goose grass (collected from Guangdong, identified by Mai Zhenqiu, senior engineer of Guangzhou Medicinal Materials Company), pass through a 60-mesh sieve, and place in CO 2 In the supercritical extraction apparatus, the extraction pressure was 40 MPa, the extraction temperature was 50°C, the flow rate was 30 liters / hour, and the extraction time was 4 hours, the CO 2 Supercritical extract 22.6g.

Embodiment 3

[0033] Grind 300g of dried goose grass (collected from Guangdong, identified by Mai Zhenqiu, senior engineer of Guangzhou Medicinal Materials Company), pass through a 60-mesh sieve, and place in CO 2 In a supercritical extraction apparatus, the extraction pressure is 20 MPa, the extraction temperature is 30°C, the flow rate is 10 liters / hour, and the extraction time is 1 hour, the CO 2 Supercritical extract 14.6g.

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Abstract

The invention discloses the application of the CO2 supercritical extract of Goose Bubivora in the preparation of medicine or food with anti-influenza virus effect. The goose non-herbivorous extract is the extract obtained by extracting the goose non-grassy by CO2 supercritical extraction process, or the extract obtained by extracting and refining the extract with petroleum ether, cyclohexane, chloroform or benzene . The goose not herbivorous extract has a good anti-influenza virus effect, and its anti-virus effect is equivalent to or more significant than the positive control drug ribavirin, and has good medical application value. The invention provides a strong technical basis for developing the plant resources that geese do not eat grass.

Description

technical field [0001] The present invention relates to the technical field of medicine, more specifically, relates to a kind of goose does not eat grass CO 2 Application of supercritical extract in preparing medicine or food with anti-influenza virus effect. Background technique [0002] Influenza viruses are a major threat to human health. The respiratory disease caused by influenza virus is called influenza (flu), which has the characteristics of wide prevalence, strong infectivity and high incidence. According to statistics, there are 600-1200 million influenza cases in the world every year, of which 3-5 million are severe influenza cases, 250-500,000 people die, and the case fatality rate of severe influenza can reach 10%. As a viral infectious disease, influenza not only seriously threatens the health of the people, but also brings a heavy burden to the country and society. How to effectively prevent and treat influenza, especially highly pathogenic influenza, has be...

Claims

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Application Information

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Patent Type & AuthorityPatents(China)
IPC IPC(8): A61K36/28A23L1/29A23L2/38A61P31/16A23L33/00
Inventor王国才李药兰李国强吴鹏张晓丽洪艺蕾
OwnerJINAN UNIVERSITY