Retinal prosthesis with spherical arc substrate

A retinal prosthesis and retinal technology, applied in the field of visual prosthesis, can solve the problems of electrode array fabrication and splicing, the difficulty of fixing, and the complex structure, and achieve the effects of improving the efficiency of electrical stimulation, increasing the difficulty, and improving the stimulation efficiency.

Inactive Publication Date: 2014-04-02
INST OF BIOMEDICAL ENG CHINESE ACAD OF MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the array can provide a large spatial field of view, its structure is relatively complicated, and the fabrication, implantation, and post-implantation splicing and fixation of the electrode array are difficult.

Method used

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  • Retinal prosthesis with spherical arc substrate
  • Retinal prosthesis with spherical arc substrate
  • Retinal prosthesis with spherical arc substrate

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Embodiment Construction

[0028] Embodiments of the present invention will be described in further detail below in conjunction with the accompanying drawings.

[0029] A retinal prosthesis with a spherically curved substrate, such as figure 1 As shown, it includes the microelectrode array 1 implanted in the retina, the microelectrode array lead-out part 2 and the external electrical stimulation introduction part 3. The above three parts can be made in one piece, and the overall thickness is not greater than 20 μm. The microelectrode array implanted in the retina is a spherical arc-shaped retinal surface micro-electrode array, and the electrode array is installed in different arrangements on a spherical arc-shaped polychlorinated xylene (parylene) substrate with biocompatibility Microelectrode array, each electrode point has a lead wire, the microelectrode array on the surface of the spherical arc retina can be implanted in the retina, and the electrical stimulation signal from the outside acts on the c...

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Abstract

The invention relates to a retinal prosthesis with a spherical arc substrate. The retinal prosthesis comprises a microelectrode array, a microelectrode array outgoing line portion and an external electrical stimulation lead-in portion. The retinal prosthesis is mainly technically characterized in that the microelectrode array is arranged on the surface of the spherical arc retinal prosthesis. The center of the retinal prosthesis is more effectively fitted with the surface of the retinal prosthesis by the aid of the microelectrode array on the surface of the spherical arc retinal prosthesis, a microelectrode is arranged on a spherical arc convex surface, so that the microelectrode can effectively contact with the surface of the retinal prosthesis, electrical stimulation efficiency is improved, stimulation current of the microelectrode array on the surface of the retinal prosthesis is reduced, the service time of the microelectrode array is prolonged, the retinal prosthesis is effectively protected, and spherical arc polychlorostyrene with biocompatibility replaces xylene materials and serves as a flexible substrate, so that manufacture and implantation of the electrode array are facilitated.

Description

technical field [0001] The invention belongs to the technical field of visual prosthesis, in particular to a retinal prosthesis with a spherical arc substrate. Background technique [0002] Retinal Prothesis (Retinal Prothesis) is aimed at specific retinal lesions. Microelectrode arrays are implanted in the retina to stimulate the surviving rods and cones to form optical information in the brain. Age-related macular degeneration (AMD) and retinitis pigmentosa (RP) degenerate cone cells and rod cells to varying degrees, resulting in vision loss or blindness; however, the optic nerve is not damaged and can still transmit electrical signals from the retina to brain. The principle of the visual prosthesis is to encode the light signal into an electrical stimulation signal, and then apply the electrical signal to the retina by the retinal microelectrode array, and stimulate the undamaged visual cells of the retina to cause an electrical response signal part, and the electrical r...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F9/08A61F2/14A61N1/36
Inventor 谢小波崔红岩徐圣普胡勇冯莉
Owner INST OF BIOMEDICAL ENG CHINESE ACAD OF MEDICAL SCI
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