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Anti-inflammatory and liver-protecting traditional Chinese medicine composition and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of anti-inflammatory and liver-protecting traditional Chinese medicine composition and its preparation, can solve problems such as low extraction rate, influence on drug efficacy, and failure to propose active ingredients, and achieve excellent curative effect, reduction of necrotic foci, and liver The effect of the relative alignment of cell cords

Active Publication Date: 2016-04-27
GUANGXI WUZHOU PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0018] Due to the different properties of the active ingredients in the eight-flavored medicinal materials, if the preparation methods in the above patents all use water extraction, some active ingredients cannot be extracted, or the extraction rate is low, which will affect the efficacy of the drug.

Method used

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  • Anti-inflammatory and liver-protecting traditional Chinese medicine composition and preparation method thereof
  • Anti-inflammatory and liver-protecting traditional Chinese medicine composition and preparation method thereof
  • Anti-inflammatory and liver-protecting traditional Chinese medicine composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0080] 1) Take the following medicinal materials in parts by weight: 456g of Desmodium glabra, 302g of Corn Stigma, 228g of Shiwei, 228g of Chicken Bone Grass, 228g of Poria Cocos, 165g of Plantain, 165g of Sea Golden Sand Grass, 228g of Imperata Rhizome;

[0081] 2) Extract 2 times with citric acid-ethanol solution of Chickweed, adding 20 times and 15 times of the total weight of medicinal materials respectively in 10% ethanol solution of 0.1% citric acid, each extraction time is 4 hours and 2 hours respectively, Combine the extracts, filter, and concentrate the filtrate into a liquid extract;

[0082] 3) Plantago was extracted twice with sodium bicarbonate-ethanol solution, each time adding 0.1% sodium bicarbonate 10% ethanol solution 20 times and 15 times the total weight of the medicinal materials, and the extraction time was 4 hours and 2 hours respectively. hours, combined extracts, filtered, and the filtrate was concentrated into liquid extract;

[0083] 4) Add water t...

Embodiment 2

[0086] 1) Take the following medicinal materials in parts by weight: 456g of Desmodium glabra, 302g of Corn Stigma, 228g of Shiwei, 228g of Chicken Bone Grass, 228g of Poria Cocos, 165g of Plantain, 165g of Sea Golden Sand Grass, 228g of Imperata Rhizome;

[0087] 2) Extract with citric acid-ethanol solution for 3 times, add 5% citric acid and 40% ethanol solution of 20 times, 15 times, and 8 times the total weight of the medicinal materials respectively, and the extraction time for each time is 4 hours, After 2 hours and 1 hour, the extracts were combined, filtered, and the filtrate was concentrated into a liquid extract;

[0088] 3) Plantago was extracted with sodium bicarbonate-ethanol solution for 3 times, each time adding 5% sodium bicarbonate 40% ethanol solution of 20 times, 15 times and 10 times the total weight of the medicinal materials respectively, and each extraction time was 4 hour, 2 hours, 1 hour, combine the extracts, filter, and concentrate the filtrate into ...

Embodiment 3

[0092] 1) Take the following medicinal materials in parts by weight: 456g of Desmodium glabra, 302g of Corn Stigma, 228g of Shiwei, 228g of Chicken Bone Grass, 228g of Poria Cocos, 165g of Plantain, 165g of Sea Golden Sand Grass, 228g of Imperata Rhizome;

[0093] 2) Extract with citric acid-ethanol solution for 3 times, adding 0.5% citric acid and 20% ethanol solution of 20 times, 15 times, and 10 times the total weight of the medicinal materials respectively, and the extraction time for each time is 3 hours, After 2 hours and 1 hour, the extracts were combined, filtered, and the filtrate was concentrated into a liquid extract;

[0094] 3) Plantago was extracted with sodium bicarbonate-ethanol solution for 3 times, adding 0.5% sodium bicarbonate in 30% ethanol solution of 20 times, 15 times and 10 times the total weight of the medicinal materials respectively, and each extraction time was 3 hour, 2 hours, 1 hour, combine the extracts, filter, and concentrate the filtrate into...

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Abstract

The invention relates to a traditional Chinese medicine composition for achieving anti-inflammatory and liver-protection effects and a preparation method of the traditional Chinese medicine composition. The preparation method comprises the steps of taking Desmodium styracifolium, corn stigma, pyrrosia lingua, Abrus cantoniensis Hance, Poria cocos, plantain herb, Lygodium japonicum Sw and lalang grass rhizome, wherein the Abrus cantoniensis Hance is extracted by a citric acid-ethanol solution, the plantain herb is extracted by a sodium bicarbonate-ethanol solution, and the Desmodium styracifolium, the Lygodium japonicum Sw, the pyrrosia lingua, the corn stigma, the lalang grass rhizome and the Poria cocos are extracted by water; and finally combining fluid extracts obtained by the three extraction methods. The animal pharmacological experiments and clinical test results prove that the traditional Chinese medicine composition has excellent anti-inflammatory and liver-protection effects superior to the prior art when being used for treating lithiasis in urinary system.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating calculi in the urinary system, in particular to an anti-inflammatory and liver-protecting traditional Chinese medicine composition and a preparation method thereof. Background technique [0002] Urinary system stones belong to the scope of "sand stranguria", "stone stranguria" and "blood stranguria" in TCM gonorrhea, mainly including 4 syndrome types: [0003] (1) Qi stagnation and blood stasis type: Symptoms include dull pain in the waist, dull pain, normal or tight pulse, and normal tongue; or sudden interruption of urination during drowning, severe pain that extends to the waist and abdomen, and the pain is relieved after the discharge of sand and stones; or Pain in the waist and flanks, which is like twisting, causing the lower abdomen, frequent attacks, pale complexion, cold sweat, nausea, accompanied by blood in the urine or yellowish urine, dark red tongue or petech...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P13/04A61P1/16A61P29/00
Inventor 刘冠萍张栩颜郑志远林艳英吴赛春梁云飞严灿梅
Owner GUANGXI WUZHOU PHARMA GRP
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