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Hemodialysis concentrate and preparation method thereof

A technology of hemodialysis and concentrated solution, applied in the field of medicine, can solve the problems of short shelf life and easily exceeding the limit of microorganisms, and achieve the effects of increasing safety, prolonging the validity period of storage and good sterilization effect.

Active Publication Date: 2015-10-28
GUANGZHOU KONCEN BIOSCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In the prior art, methods such as filtration are usually used to sterilize the concentrated solution. This method of disinfection can also obtain qualified products, but its shelf life is short, and the limit of microorganisms in the process of product storage is easy to exceed the standard.

Method used

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  • Hemodialysis concentrate and preparation method thereof
  • Hemodialysis concentrate and preparation method thereof
  • Hemodialysis concentrate and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0050] A preparation method of a hemodialysis concentrate in this embodiment comprises the following steps (such as figure 1 shown):

[0051] (1) Put the raw materials of hemodialysis A concentrated solution into the liquid mixing tank and stir and dissolve to prepare 100L of A concentrated solution;

[0052] (2) The solution in the liquid distribution tank is subjected to secondary filtration with filter elements of 1 μm and 0.22 μm;

[0053] (3) Mix the solution in the liquid distribution tank with the ozone generated by the ozone generator (filtered by a 0.22μm filter element) through a gas-liquid mixing pump and then input it into the storage tank. The pumping flow rate is 500L / h, and the ozone generated by the ozone generator Pass it into the gas-liquid mixing pump through the pipeline, fully mix and sterilize with the concentrated liquid A in the pump;

[0054] (4) The solution in the storage tank is pumped back to the liquid distribution tank by the circulation pump; ...

Embodiment 2

[0061] A kind of preparation method of hemodialysis concentrate of the present embodiment comprises the following steps:

[0062] (1) Put the raw materials of hemodialysis A concentrated solution into the liquid mixing tank and stir and dissolve to prepare 100L of A concentrated solution;

[0063] (2) The solution in the liquid distribution tank is subjected to secondary filtration with filter elements of 1 μm and 0.22 μm;

[0064] (3) Mix the solution in the liquid distribution tank with the ozone generated by the ozone generator (filtered by a 0.22μm filter element) through the gas-liquid mixing pump and then input it into the storage tank. The pumping flow rate is 400L / h, and the ozone generated by the ozone generator Pass it into the gas-liquid mixing pump through the pipeline, fully mix and sterilize with the concentrated liquid A in the pump;

[0065] (4) The solution in the storage tank is pumped back to the liquid distribution tank by the circulation pump;

[0066] (...

Embodiment 3

[0072] A kind of preparation method of hemodialysis concentrate of the present embodiment comprises the following steps:

[0073] (1) Put the raw materials of hemodialysis B concentrate into the liquid mixing tank and stir to dissolve, prepare 100L of B concentrate;

[0074] (2) The solution in the liquid distribution tank is subjected to secondary filtration with filter elements of 1 μm and 0.22 μm;

[0075] (3) Mix the solution in the liquid distribution tank with the ozone generated by the ozone generator (filtered by a 0.22μm filter element) through a gas-liquid mixing pump and then input it into the storage tank. The pumping flow rate is 500L / h, and the ozone generated by the ozone generator Pass through the pipeline into the gas-liquid mixing pump, fully mix and disinfect with the B concentrate in the pump;

[0076] (4) The solution in the storage tank is pumped back to the liquid distribution tank by the circulation pump;

[0077] (5) The solutions in the liquid mixin...

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Abstract

The invention discloses a preparation method of a hemodialysis concentrated solution. The preparation method comprises the following steps that (1) the hemodialysis concentrated solution is prepared in a solution mixing tank; (2) the solution in the solution mixing tank is subjected to second-level filtration; (3) the solution in the solution mixing tank and ozone generated in an ozone generator are input to a storage tank after being mixed through a gas and liquid mixing pump; (4) the solution in the solution mixing tank is pumped back to the solution mixing tank through a circulation pump; (5) the solutions in the solution mixing tank and the storage tank are mixed in a circulative mode until the ozone concentration of the solution in the storage tank reaches 0.050-0.100 mg / L; (6) the hemodialysis concentrated solution is obtained through filling. The preparation method is simple in operation, quick, efficient, and easy to industrialize. Compared with a conventional method, according to products prepared through the method, initial contaminating bacteria in the concentrated solution are reduced, the storage period is prolonged, product quality is better guaranteed, and using safety of a patient is guaranteed.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a hemodialysis concentrate and a preparation method thereof. Background technique [0002] Hemodialysis concentrate contains A concentrate and B concentrate. A concentrate is mainly composed of sodium chloride, potassium chloride, calcium chloride, magnesium chloride, acetic acid and purified water. B concentrate is composed of sodium bicarbonate and purified water. . In hemodialysis, concentrated solution A and concentrated solution B are used together to form dialysate. Its main function is to correct electrolyte and acid-base balance disorders of dialysis patients and remove metabolic waste in the body. [0003] During the hemodialysis process, the dialysate and the blood undergo material exchange through the dialyzer filter membrane, and some low-molecular substances can freely pass through the dialyzer filter membrane, enter the dialysate from the blood or enter the blood ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61M1/14A61L2/20A61L101/10
CPCA61M1/1656
Inventor 陈校园许春生匡卫文姚孝成刘春苗
Owner GUANGZHOU KONCEN BIOSCI
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