Method for treating capillary hemangiomas
A technology of capillaries and medicinal salts, applied in cardiovascular system diseases, X-ray/γ-ray/particle irradiation therapy, pharmaceutical formulations, etc., can solve side effects and other problems
Inactive Publication Date: 2014-06-25
GALDERMA SA
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Problems solved by technology
Although encouraging results have been observed with interferon, it is associated with serious side effects such as leukopenia and neurotoxicity, eg, spastic diplegia
Method used
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Embodiment 1a
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Embodiment 1b
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Embodiment 1c
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The invention relates to a method of treating capillary hemangiomas in a human in need thereof by topically administering an effective amount of one or more alpha-2 adrenergic receptors agonist to the site of the capillary hemangiomas on the skin of the human.
Description
[0001] Citations to Related Applications [0002] This application claims the benefit of US Provisional Patent Application Serial No. 61 / 548,838, filed October 19, 2011, the entire contents of which are incorporated herein by reference. Background technique [0003] Capillary hemangioma, also known as berry nevus, infantile hemangioma, juvenile hemangioma, hemangioblastoma, benign hemangioendothelioma, hypertrophic hemangioma, is the most common skin appendage of the face, orbit, and eye in children Organ tumor. Overt capillary hemangiomas have been reported in as many as 10% of all children under 1 year of age. In preterm infants less than 1000 g, the incidence of these lesions was even higher, reaching 23%. Capillary hemangiomas are benign, invasive neoplasms composed of intersecting blood vessels. They can exist as small discrete lesions or as large unsightly lumps that may obstruct vision and / or cause amblyopia. [0004] The natural history of capillary hemangiomas inc...
Claims
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IPC IPC(8): A61K31/4174A61K31/498A61P9/00
CPCA61K31/137A61K31/165A61K31/498A61K31/4174A61K31/155A61P43/00A61P9/00A61P9/14A61B18/20A61K9/0014A61K38/212A61K45/06A61N5/10
Inventor 沃伦·J·舍雷尔
Owner GALDERMA SA