Synchronous photodynamic therapy device

A technology of photodynamic therapy and treatment device, applied in the direction of light therapy, etc., can solve the problems of limited adjustment ability and uncomfortable personalized treatment plan.

Inactive Publication Date: 2014-07-16
BEIJING INSTITUTE OF TECHNOLOGYGY
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Problems solved by technology

The requirements of the existing photodynamic therapy equipment on the light source are mainly limited to the output light powe

Method used

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Embodiment Construction

[0011] The present invention will be described in further detail below in conjunction with the accompanying drawings and examples. Here, the exemplary embodiments of the present invention and their descriptions are used to explain the present invention, but not to limit the present invention.

[0012] Before the first use, the system first completes the calibration of internal optical parameters. That is, under the control of the computer (2) the image sensor takes a series of correction plate images through the (4) monitoring lens, and obtains the optical correction parameters of the (2) image sensor through the (4) monitoring lens, such as focal length, radial distortion, shear parameters such as distortion; secondly, (3) the spatial light modulator projects a series of coded images through (5) the therapeutic light projection lens (refer to Figure 4 (b)(c)(d)(e)) to the correction plate or flat reflector (such as a screen), and simultaneously acquire (2) a series of captu...

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Abstract

The invention relates to a synchronous photodynamic therapy device. The synchronous photodynamic therapy device can be used for synchronously controlling light illuminating power of a therapy light source according to the blood oxygen concentration in a diseased area of a patient under the control of a computer and can also be used for adjusting time and space distribution parameters of the light illuminating power in a therapy area through a spatial light modulator, or adjusting the light illuminating power of the therapy light source in a light source modulation method through cooperation of the computer and the spatial light modulator. In addition, according to the synchronous photodynamic therapy device, multiple spectrum structures can be adopted in the therapy light source, blood oxygen spatial distribution parameters of a treated part can be obtained through structured light illumination, then the space and time distribution of therapy light in the therapy area can be controlled, optimal matching of photosensitizer, light and oxygen can be achieved, and harmful effects of the photothermal effect and photochemical toxicity of the photosensitizer on peripheral tissues can be reduced.

Description

technical field [0001] The invention relates to a synchronous photodynamic therapy device, in particular to using photodynamic method to treat body surface diseases, such as port wine stain, basal cell carcinoma, solar keratosis, cutaneous squamous cell carcinoma, acne and the like. Background technique [0002] Photodynamic therapy is a new technology for disease diagnosis and treatment by using photosensitizers and light radiation to generate photodynamic reactions. Repeated treatment with minimal side effects. The principle of photodynamic therapy is to irradiate the lesion area with light of a specific wavelength, and finally produce a series of photochemical reactions. The products (excited singlet oxygen molecules) have strong oxidative properties, which can kill diseased cells and achieve the purpose of treatment. . [0003] The efficacy of photodynamic therapy involves three key factors: photosensitizer, light and oxygen molecules in cells. Currently, commonly use...

Claims

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Application Information

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IPC IPC(8): A61N5/06
Inventor 胡晓明张凤娟李勤曹群
Owner BEIJING INSTITUTE OF TECHNOLOGYGY
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