Capsule capable of reducing incidence rate of postoperative shivering and preparation method thereof

Abstract

The invention discloses a capsule capable of reducing an incidence rate of postoperative shivering and a preparation method thereof. The preparation method is characterized by comprising the following steps: (1) respectively distilling coarse powder of glabrous sarcandra herb, changnienia amoena, rhizoma anemones altaicae, poncirus bark, asaraceae and erythrinae bark through steam, extracting volatile oil, collecting and mixing the volatile oil for later use, and reserving dregs for later use; (2) uniformly mixing satyrium root, spina gleditsiae, rhizoma cimicifugae, fragrant sarcococca herb, amblystegium serpens and buckeye seeds with the dregs obtained from the step 1, adding 4 times of water, decocting twice in water with each time lasting for 1 hour, combining decoctions and standing; then adding 95% ethanol which is 3-4 times as much as the decoction to the decoction, standing for 15 minutes, centrifuging for 20 minutes at 3000rpm / min, reserving a centrifugal solution, concentrating and spray-drying the centrifugal solution to obtain a primary material; and (3) spraying the volatile oil obtained from the step 1 into the primary material obtained from the step 2, uniformly mixing and grinding, filtering through a 60-mesh sieve, and filling in capsules. Clinical experiments prove that the capsule disclosed by the invention has the characteristics of a good curative effect and a relatively high safety on preventing shivering after idiopathic general anesthesia; the capsule is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a capsule capable of reducing the incidence of postoperative shivering and a preparation method thereof. Background technique [0002] The use of anesthesia can allow patients to perform surgical operations in a sedative, painless and comfortable state, but anesthesia drugs will not only affect consciousness and change pain cognition, but also interfere with normal physiological functions of patients, such as heartbeat, blood pressure, Breathing etc. [0003] The incidence of postanesthesia shivering (PS) after idiopathic general anesthesia has been reported in previous literatures, ranging from 5% to 38% in general surgery and 13% to 65% in craniotomy. The so-called idiopathic chills after general anesthesia, also known as "thiopental-like rigidity", is a complication of anesthesia. Shivering under physiological conditions is the body's compensatory response to hypo...

AI Technical Summary

Problems solved by technology

However, when shivering occurs, it will be accompanied by an increase in the cardiopulmonary load caused by a significant increase in the body's metabolic rate;