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Preoperative intervention medicine composition for neurosurgery and preparation method of composition

A technology of neurosurgery and composition, which is applied in the field of neurosurgery preoperative intervention pharmaceutical composition and its preparation, which can solve problems such as increased cardiopulmonary load, myocardial ischemia, and damage to platelet function, and achieve increased walking efficacy, flat and sweet taste Effect

Inactive Publication Date: 2014-07-23
车树圣
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, when shivering occurs, it will be accompanied by an increase in the cardiopulmonary load caused by a significant increase in the body's metabolic rate;

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Example 1, the weight ratio of raw materials: 20 parts of ginseng, 10 parts of orchid, 6 parts of saponins, 10 parts of Cimicifuga, 6 parts of pangolin, 10 parts of osmanthus, 10 parts of sarcophagus, citrus aurantii 10 parts, 10 parts of Iris calamus, 2 parts of Du Heng, 6 parts of willow moss, 20 parts of loofah.

[0031] The preparation method of Example 1 is: mix the paired ginseng, uniflora, saponins, cohosh, pangolin, osmanthus, sarcocarp, hovenia trifoliata, iris calamus, Du Heng, willow moss, and loofah Add water to decoct, take the filtrate after 30 minutes, add water to the medicinal dregs and continue decocting for 20 minutes, then take the filtrate, combine the two filtrates, divide into two parts and take it in the morning and evening.

Embodiment 2

[0032] Example 2, the weight ratio of raw materials: 10 parts of ginseng, 6 parts of Cymbidium chinensis, 3 parts of saponins, 6 parts of Cimicifuga, 3 parts of pangolin, 6 parts of Qingxianggui, 6 parts of sarcophagus, 6 parts of Zhiru 6 parts, 6 parts of Iris calamus, 1 part of Du Heng, 3 parts of willow moss, 10 parts of loofah.

Embodiment 3

[0033] Example 3, the weight ratio of raw materials: 20 parts of ginseng, 10 parts of orchid, 6 parts of saponins, 10 parts of Cimicifuga, 6 parts of pangolin, 10 parts of osmanthus, 10 parts of sarcophagus, citrus aurantii 10 parts, 10 parts of Iris calamus, 2 parts of Du Heng, 6 parts of willow moss, 20 parts of loofah.

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PUM

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Abstract

The invention discloses a preoperative intervention medicine composition for neurosurgery and a preparation method of the composition so as to solve the problem of prevention of shiver after idiopathic general anesthesia. The preparation method of the preoperative intervention medicine composition is characterized by comprising the following steps: (1) respectively distilling sarcandra glabra, changnienia amoena, irkutsk anemone rhizome, poncirus bark, fragrant sarcococca herb and asarum forbesii coarse powder by using steam so as to extract volatile oil, collecting the volatile oil, mixing for later use, and reserving medicine residues for later use; (2) uniformly mixing satyrium root, spina gleditsiae, rhizoma cimicifugae, amblystegium serpens, pangolin and loofah sponge with the medicine residues obtained in the step 1, adding 4 times amount of water, adding water so as to decoct two times, decocting for one hour each time, combining decoction, and standing still, then adding 95% alcohol, the amount of which accounts for 3-4 times of the amount of liquid medicine to the decoction, standing still for 15 minutes, then centrifuging for 20 minutes at the speed of 3000rpm / min, taking centrifugate, concentrating and carrying out spray drying so as to obtain a primary material; and (3) spraying the volatile oil obtained in the step (1) into the primary material obtained in the step (2), uniformly mixing, grinding, sieving by using a 60-mesh sieve, and capsuling. The clinical experiment shows that the preoperative intervention medicine composition for prevention of shiver after idiopathic general anesthesia is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a neurosurgery preoperative intervention drug composition and a preparation method thereof. Background technique [0002] Neurosurgery, especially for patients involving craniotomy, due to anesthesia, trauma, high intracranial pressure, tracheal tube stimulation, and external factors, postoperative complications are much higher than other surgical operations. For example, the incidence of postanesthesia shivering (PS) after idiopathic general anesthesia has been reported in previous literatures, which is 5% to 38% in general surgery and 13% to 65% in craniotomy. The so-called idiopathic chills after general anesthesia, also known as "thiopental-like rigidity", is a complication of anesthesia. Shivering under physiological conditions is the body's compensatory response to hypothermia, which produces heat through rapid rhythmic contraction of skeletal muscles. The mech...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61P43/00A61K35/36
Inventor 郑洪彩徐夕升高治民王春爱
Owner 车树圣
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