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Cell Composite Force-Electrical Loading Measurement Device

A compound force, cell technology, applied in the field of cell engineering

Inactive Publication Date: 2016-03-30
XIAMEN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to solve the technical problem that the existing devices cannot provide precise electromechanical combined stimulation for a type of suspension cells such as egg cells, thereby proposing a combined electromechanical loading test device for single cells

Method used

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  • Cell Composite Force-Electrical Loading Measurement Device
  • Cell Composite Force-Electrical Loading Measurement Device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] refer to figure 1 with figure 2 As shown, the device for cell composite force-electric loading measurement in this embodiment includes: a mechanical transmission system, a mechanical transmission control system, electrode probes, a cell placement platform, an electrical signal generation system, and a piezoelectric measurement system. in:

[0035] The mechanical transmission system includes a mechanical action generating device and an operating arm 5 connected to the mechanical action generating device. The mechanical action generating device is used to drive the operating arm 5 to perform spatial displacement actions. The mechanical action generating device is a three-dimensional action generating device (a one-dimensional or two-dimensional action generating device can be used according to actual needs). Such as figure 1 As shown, the three-dimensional action generating device includes: a first linear displacement component located on the X axis, a second linear dis...

Embodiment 2

[0050]This embodiment is basically the same as Embodiment 1, except that the electrode probes are not connected to an electrical signal generating system, but are connected to an electrical signal measuring system, so that bioelectrical signals fed back by cell stimulation can be collected. Specifically, this embodiment includes: a mechanical transmission system, a mechanical transmission control system, an electrode probe, a cell placement platform, an electrical signal measurement system, and a piezoelectric measurement system. in:

[0051] The mechanical transmission system includes a mechanical action generating device and an operating arm connected to the mechanical action generating device. The mechanical action generating device is used to drive the operating arm to perform a displacement action in space.

[0052] The mechanical transmission control system is in control connection with the mechanical action generating device, and is used to drive the mechanical action g...

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Abstract

The invention belongs to the technical field of cell engineering, and particularly relates to a cytomechanic-electrical joint loading and analyzing device in a biomedical experimental instrument. The invention discloses a device for cell composite force-electric load measurement. The device comprises a mechanical drive system, a mechanical drive control system, an electrode probe, a cell placement platform, an electric signal generation system and a piezoelectric measurement system. The invention also discloses a device for cell composite force-electric load measurement. The device for cell composite force-electric load measurement comprises a mechanical drive system, a mechanical drive control system, an electrode probe, a cell placement platform, an electric signal measuring system and a piezoelectric measurement system. The devices disclosed by the invention are applied to an application prospect for cytomechanic-electrical load measurement on cells.

Description

technical field [0001] The invention belongs to the technical field of cell engineering, in particular to a cell mechanics-electricity combined loading and analysis device in a biomedical experimental instrument. Background technique [0002] Cell mechanics is a rapidly developing frontier topic in the field of biomechanics in the past few years. It mainly studies the structural and functional changes of cells under mechanical stimulation. Studying the mechanical properties of biological cells is of great significance to cell physiology, pathological process research, disease diagnosis and treatment, cell quality evaluation and analysis, etc. In the field of reproductive medicine and developmental biology, the structural and biochemical changes in the process of cell development are often studied through the change of the elastic coefficient of the zona pellucida of egg cells. The elastic coefficient of the zona pellucida of egg cells is considered to be an important indica...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12M1/42
CPCC12M35/02C12M35/04C12M41/00
Inventor 谢瑜刘翀
Owner XIAMEN UNIV
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