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Traditional Chinese medicinal composition for treating coronary heart disease

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition, can solve the problems of lack of improvement of coronary heart disease, abnormal activity endurance, lack of improvement of microcirculation disorder, etc., to achieve improvement of coronary microcirculation state, improvement of cardiac function reserve, and protection of cardiac muscle. Effect

Inactive Publication Date: 2014-08-20
GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Lack of drugs to improve microcirculatory disturbance in coronary heart disease, and lack of drugs to improve abnormal activity tolerance of coronary heart disease

Method used

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  • Traditional Chinese medicinal composition for treating coronary heart disease
  • Traditional Chinese medicinal composition for treating coronary heart disease
  • Traditional Chinese medicinal composition for treating coronary heart disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Raw material ratio:

[0027] 5 parts of American ginseng, 5 parts of ginseng, 10 parts of herb, 5 parts of Panax notoginseng, 6 parts of Pinellia chinensis, 3 parts of leech, and 15 parts of lotus leaf.

[0028] Preparation Process:

[0029] 1) Water decoction: take American ginseng, ginseng, atractylodes atractylodes, Panax notoginseng, Pinellia and lotus leaves, add water, decoct in a slightly boiling state for 1 hour, decoct twice, combine the filtrates, concentrate, spray dry, and obtain powder 1;

[0030] 2) leech: freeze-dried, pulverized to obtain leech powder;

[0031] 3) Mixing: Mix the powder 1 and the leech powder, and granulate to obtain a granule, which is recorded as Shenshu Guanxin Fang traditional Chinese medicine compound granule.

Embodiment 2

[0033] Raw material ratio:

[0034] 4 parts of American ginseng, 4 parts of ginseng, 12 parts of herb, 5 parts of Panax notoginseng, 7 parts of Pinellia chinensis, 3 parts of leeches, and 204 parts of lotus leaves.

[0035] Preparation Process:

[0036] 1) Take American ginseng, ginseng, atractylodes atractylodes, Panax notoginseng, Pinellia and lotus leaves, add water, decoct each for 1 hour in a slightly boiling state, decoct twice, combine the filtrates, concentrate, and spray dry to obtain powder 1;

[0037] 2) leech: freeze-dried, pulverized to obtain leech powder;

[0038] 3) Mixing and making tablets: mixing the powder 1 and leech powder, and pressing into tablets to obtain tablets.

Embodiment 3

[0040] Raw material ratio:

[0041] 3 parts of American ginseng, 5 parts of ginseng, 11 parts of herb, 4 parts of Panax notoginseng, 5 parts of Pinellia chinensis, 3.5 parts of leech, and 15 parts of lotus leaf.

[0042] Preparation Process:

[0043] 1) Take American ginseng, ginseng, and herb, add water, decoct for 1.5 hours at a slight boil, decoct twice, and combine the filtrate; add water with Panax notoginseng, Pinellia and lotus leaves, decoct for 1 hour at a slight boil, and decoct twice , combined filtrates; combined all filtrates were concentrated, spray-dried to obtain powder 1;

[0044] 2) Leech: dry at no more than 80°C and crush to obtain leech powder;

[0045] 3) Mixing: Mix the powder 1 and the leech powder, fill it, and obtain capsules.

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Abstract

The invention discloses a traditional Chinese medicinal composition for treating the coronary heart disease. The effective components of the composition are extracted from American ginseng, ginseng, Atractylodes lancea, Panax Notoginseng, Rhizoma Pinelliae Preparatum, leech and lotus leaf. The traditional Chinese medicinal composition can obviously improve the cardiac function reserve and coronary microcirculation state of a myocardial infarction rat model in order to realize myocardial ischemia resistance and myocardial protection effects. The traditional Chinese medicinal composition improves the angina pectoris symptoms of coronary heart disease patients with stable angina pectoris, improves the cardiac function, improves the daily exercise tolerance, protects the gastrointestinal function, improves the quality of life, improves traditional Chinese medicinal diseases, has no obvious influences on the blood pressure or the hear rate, has high compliance, and has no obvious toxic side effects of untoward effects.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating coronary heart disease. Background technique [0002] "China Cardiovascular Disease Report 2008-2009" statistics show that the incidence and mortality of cardiovascular diseases in my country are on the rise, and at least 500,000 people suffer from myocardial infarction every year. The results of the 2010 China Health Statistical Yearbook show that heart disease is the second cause of death among urban residents in my country, accounting for 20.77% of all deaths, of which the mortality rate of coronary heart disease is 94.96 / 100,000; it is the third cause of death among rural residents, It accounted for 17.21% of all deaths, and the death rate of coronary heart disease was 71.27 / 100,000. [0003] Coronary heart disease has become a common and frequently-occurring disease in my country, seriously endangering peopl...

Claims

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Application Information

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IPC IPC(8): A61K36/8888A61P9/10A61K35/62
Inventor 吴焕琳徐丹苹阮新民罗文杰王侠李晓庆
Owner GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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