Brain functional connection detection method and system based on near-infrared spectroscopy

A technology of brain functional connectivity and near-infrared spectroscopy, which is applied in the field of brain functional connectivity detection and systems based on near-infrared spectroscopy, can solve the problems of complex detection methods, expensive equipment, processing and analysis of cerebral blood oxygen content, etc. High reliability, simple non-invasive detection method, simple and convenient method

Inactive Publication Date: 2016-05-04
SHANDONG UNIV
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Problems solved by technology

Patent No. CN1891144AA proposes a cerebral apoplexy early warning detector based on cerebrovascular hemodynamic monitoring parameter information. The detection method is complicated and the equipment is expensive; device that can synchronize multimodal measurements with other instruments, but does not directly process analysis of cerebral blood oxygen content
Patent No. CN103156620A proposes a multi-channel brain function near-infrared spectral imaging system based on phase-sensitive detection technology. This system can perform imaging analysis on brain function, but the analysis process is complicated and there are many supporting equipment

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  • Brain functional connection detection method and system based on near-infrared spectroscopy
  • Brain functional connection detection method and system based on near-infrared spectroscopy
  • Brain functional connection detection method and system based on near-infrared spectroscopy

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Embodiment Construction

[0036] The present invention will be further described below in conjunction with the accompanying drawings and embodiments.

[0037] The present invention collects the brain oxygen content of left and right frontal lobes of different groups of people by using near-infrared spectrum, analyzes and processes the spectra by wavelet coherence method (WCO) and wavelet phase coherence method (WPCO), and establishes a PLS correction model. When detecting the people to be tested, it is only necessary to collect the brain oxygen signals of the left and right prefrontal lobes of the tested people, perform WCO and WPCO processing, and substitute them into the established PLS model to automatically calculate the brain functional connection detection index.

[0038] Such as figure 1 As shown, two photoelectric sensors were placed on the left and right frontal regions of the brain, and a cerebral oximeter was used to detect the blood oxygen parameters of the brain tissue. Cerebral blood oxy...

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Abstract

The invention discloses a brain function connection detection method and a brain function connection detection system based on the near infrared spectrum. The method comprises the steps that the near infrared spectrum is utilized to collect the blood oxygen parameter of a time sequence function, the function is then imported into wavelet coherence and wavelet phase position coherence analysis software for time-frequency domain conversion, meanwhile, the brain oxygen parameter wavelet phase coherence coefficient and wavelet phase position coherence parameter under different feature frequencies are calculated, and then the two coefficients are input to a brain function connection detection model established on the basis of a partial least square method, and then the detection result of the brain function connection feature of a tester is provided. With the brain function connection detection method and the brain function connection detection system based on near infrared spectrum, the brain blood oxygen signals of left and right prefrontal lobes are monitored at the same time, and the method is simple and convenient; in monitoring, a photoelectric sensor only needs to be placed at the positions of the left and right prefrontal lobes of the tester, so that the brain oxygen parameter of the tester can be obtained in real time through the near infrared spectrum method, and the anti-interference performance is strong; the sensitivity and reliability of the monitoring index are high.

Description

technical field [0001] The invention relates to a method and system for detecting brain functional connection based on near-infrared spectroscopy. Background technique [0002] At present, brain functional connectivity disorder is one of the important reasons that affect people's healthy life quality, especially the prefrontal cortex functional connectivity plays an important role in people's cognition and posture balance. By using a simple and non-invasive method to detect brain functional connectivity, brain function can be monitored early and brain dysfunction can be prevented. [0003] Current noninvasive methods for studying brain function mainly include functional magnetic resonance (fMRI), positron emission tomography (PET), electroencephalography (EEG), event-related potential (ERP), magnetoencephalography (MEG) and near-infrared spectroscopy. method (NIRS). Due to the deep penetration ability of near-infrared light, and oxyhemoglobin (HbO2), which reflects brain t...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/1455G06F19/00
Inventor 李增勇韩庆宇谭启涛张曼玉王碧天
Owner SHANDONG UNIV
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