Application of cynomorium songaricum extractive in preparation of antidepressant drug

A Cynomorium extract and anti-depressant technology, which is applied in the field of medicine, can solve the problems of no public reports of Cynomorium depression drugs, no public reports of Cynomorium extract antidepressant drugs, etc., and achieve simple preparation methods, The effect of rich raw materials

Inactive Publication Date: 2014-10-01
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

With the continuous improvement of the value of Cynomorium drugs, the research on Cynomorium is increasingly valued by people, but so far there is no public report on th

Method used

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  • Application of cynomorium songaricum extractive in preparation of antidepressant drug
  • Application of cynomorium songaricum extractive in preparation of antidepressant drug
  • Application of cynomorium songaricum extractive in preparation of antidepressant drug

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Embodiment Construction

[0006] The specific implementation of the present invention will be described in detail below in combination with specific situations.

[0007] In the specific implementation of the present invention, the application of the Cynomorium extract in the preparation of antidepressant drugs, the Cynomorium extract is taken from the Cynomorium medicinal material, pulverized into coarse powder passing through a 20-30 mesh sieve, and adding 10 times the Cynomorium weight Soak in ethanol with a mass concentration of 70% for 0.5h, reflux extraction twice or twice, the first time for 1.5h, the second time for 1h, filter, combine the filtrates, recover the ethanol under reduced pressure until there is no alcohol smell, and obtain Cynomorium cynomorium extract; D -101 type macroporous adsorption resin soaked in ethanol with a mass concentration of 95% for 24 hours, then wet-packed the column, and dynamically cleaned with ethanol with a mass concentration of 95% until the ethanol eluent and w...

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Abstract

The invention relates to application of cynomorium songaricum extractive in the preparation of an antidepressant drug, can effectively solve the problem about the preparation of the antidepressant drug, and realizes the application of the cynomorium songaricum extractive in the preparation of the antidepressant drug. The cynomorium songaricum extractive is prepared through the following steps: taking cynomorium songaricum medicinal materials, smashing the cynomorium songaricum medicinal materials into coarse powder, soaking with ethyl alcohol, performing the reflux extraction, recycling the ethyl alcohol from the filtrate through pressure reduction until the alcohol taste is eliminated, so as to obtain a cynomorium songaricum extracting solution; soaking macroporous resin with ethyl alcohol, and performing wet-process packing; dispersing the cynomorium songaricum extracting solution into dispersion liquid by using distilled water, adjusting the pH value to 4.5, adding macroporous resin columns, eluting by using distilled water, and removing the eluent; continuously eluting by using ethyl alcohol, and removing the eluent; then eluting by using ethyl alcohol again, collecting the ethyl alcohol eluent, recycling the ethyl alcohol through pressure reduction, drying, and smashing, so as to obtain the finished product. According to the invention, the prepared cynomorium songaricum extractive has the anti-depression function, and can be effectively used for preparing the antidepressant drug, so that the application of the cynomorium songaricum extractive in the preparation of the antidepressant drug is realized.

Description

technical field [0001] The invention relates to medicine, in particular to the application of Cynomorium cynomorium extract in the preparation of antidepressant medicine. Background technique [0002] Cynomorium, also known as elixir, is a perennial succulent parasitic herb. A parasitic plant that grows wild in the Gobi desert, where it grows best at minus 20°C, where there is no snow and the ground is not frozen. It has the effects of invigorating the kidney and moistening the intestines, curing impotence, and hematuria. With the continuous improvement of the value of Cynomorium drugs, the research on Cynomorium is increasingly valued by people, but so far there is no public report on the application of Cynomorium extracts in the preparation of antidepressant drugs, nor the preparation of Cynomorium to treat depression. Public reports of disease drugs. Contents of the invention [0003] In view of the above situation, in order to overcome the defects of the prior art, ...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61P25/24
Inventor 苗明三白明蔡源源
Owner HENAN UNIV OF CHINESE MEDICINE
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