Medical antibacterial rubber dressing as well as preparation method and application thereof

A technology of rubber and chlorinated natural rubber is applied in the field of medical antibacterial rubber dressings and the preparation of medical antibacterial rubber dressings to achieve the effects of good versatility, high barrier microorganisms and good porosity

Active Publication Date: 2014-10-01
JIANGSU RUIJING TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At the same time, there are very few high-end dressings with independent intellectual property rights in the Chinese market at present, and the use of chlorinated natural rubber as the base material to prepare modern antibacterial dressings through electrospinning technology is almost blank.

Method used

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  • Medical antibacterial rubber dressing as well as preparation method and application thereof
  • Medical antibacterial rubber dressing as well as preparation method and application thereof
  • Medical antibacterial rubber dressing as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0077] Embodiment 1: prepare medical antibacterial rubber dressing

[0078] The implementation steps of this embodiment are as follows:

[0079] A, preparation of chlorinated natural rubber solution

[0080] According to the weight ratio of chlorinated natural rubber to THF 1:5.0, the chlorinated natural rubber produced by the Product Processing Research Institute of the Chinese Academy of Tropical Agricultural Sciences, the chlorine content is 58% by weight in THF solvent, under the condition of stirring speed 300rpm Down stirring and dissolving 60min, obtain the chlorinated natural rubber solution;

[0081] B, preparation of grafted chlorinated natural rubber

[0082] According to the weight ratio of chlorinated natural rubber and allyltriphenylphosphonium bromide 1:0.6, add allyltriphenylphosphonium bromide prepared by Jinan University CN102020675B patented technology to the chlorinated natural rubber solution obtained in step A Phosphonium, mixed evenly, and then carrie...

Embodiment 2

[0089] Embodiment 2: prepare medical antibacterial rubber dressing

[0090] The implementation steps of this embodiment are as follows:

[0091] A, preparation of chlorinated natural rubber solution

[0092]According to the weight ratio of chlorinated natural rubber and THF 1:3.0, the chlorinated natural rubber produced by the Product Processing Research Institute of the Chinese Academy of Tropical Agricultural Sciences, the chlorine content is 50% by weight in THF solvent, under the condition of stirring speed 400rpm Down stirring and dissolving 50min, obtain the chlorinated natural rubber solution;

[0093] B, preparation of grafted chlorinated natural rubber

[0094] According to the weight ratio of chlorinated natural rubber and allyltriphenylphosphonium bromide 1:0.4, add allyltriphenylphosphonium bromide prepared by Jinan University CN102020675B patented technology to the chlorinated natural rubber solution obtained in step A Phosphonium, mixed evenly, and then carrie...

Embodiment 3

[0101] Embodiment 3: prepare medical antibacterial rubber dressing

[0102] The implementation steps of this embodiment are as follows:

[0103] A, preparation of chlorinated natural rubber solution

[0104] According to the weight ratio of chlorinated natural rubber to THF 1:3.6, the chlorinated natural rubber produced by the Product Processing Research Institute of the Chinese Academy of Tropical Agricultural Sciences, the chlorine content is 53% by weight in THF solvent, under the condition of stirring speed 500rpm Down stirring and dissolving 30min, obtain the chlorinated natural rubber solution;

[0105] B, preparation of grafted chlorinated natural rubber

[0106] According to the weight ratio of chlorinated natural rubber and allyltriphenylphosphonium bromide 1:0.5, add allyltriphenylphosphonium bromide prepared by Jinan University CN102020675B patented technology to the chlorinated natural rubber solution obtained in step A Phosphonium, mixed evenly, and then carrie...

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Abstract

The invention relates to a medical antibacterial rubber dressing as well as a preparation method and application thereof. The preparation method of the medical antibacterial rubber dressing comprises the following steps: preparing a chlorinated natural rubber solution, preparing grafted chlorinated natural rubber, preparing a nano zinc carbonate mixture solution and spinning. The medical antibacterial rubber dressing contains high polymer long-acting antibacterial components prepared by quaternary phosphonium cationic grafted chlorinated natural rubber as well as nano zinc carbonate. Therefore, the medical antibacterial rubber dressing has high-efficiency and synergetic effect of killing harmful microbes, has an obvious effect of killing bacteria, viruses and fungi and has the efficiency of killing staphylococcus aureus, hemolytic streptococcus, pseudomonas aeruginosa, Escherichia coli and other clinic pathogenic bacteria by over 99 percent.

Description

【Technical field】 [0001] The invention belongs to the technical field of medical drugs. More specifically, the present invention relates to a medical antibacterial rubber dressing, a method for preparing the medical antibacterial rubber dressing, and an application of the medical antibacterial rubber dressing. 【Background technique】 [0002] The skin is the largest organ of the human body, and it is an important barrier to protect the body and resist external damage. After skin trauma (operation, burn, ulcer, etc.), an artificial dressing with similar skin function is often needed to temporarily replace the skin to protect the wound, prevent infection and accelerate healing. wound healing. [0003] Traditional wound dressings include cotton gauze bandages (such as barrier dressings, woven or non-woven sponge structure cotton fabrics, etc.), bandages / rolled bandages (cotton or viscose fiber non-adhesive bandages, etc.), special dressings (protective gaskets, disinfected once...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/42A61L15/44A61L15/30A61L15/18
Inventor 汤瑞明耿在云
Owner JIANGSU RUIJING TECH DEV
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