A kind of traditional Chinese medicine composition for preparing anti-candida medicine

Abstract

The invention relates to a traditional Chinese medicine composition for preparing Candida resisting medicines. The traditional Chinese medicine composition contains the ingredients in parts by weight: 40-80 parts of cinnamaldehyde and 30-60 parts of pogostone. The traditional Chinese medicine composition for preparing the Candida resisting medicines, provided by the invention, can be used for treating deep or systemic fungal infections caused by Candida, including deep or systemic fungal infections caused by Candida albicans, Candida tropicalis, Candida krusei or Candida glabrata. According to the traditional Chinese medicine composition, the pogostone is screened from numerous ingredients of ageratum oil, has relatively high bacteriostasis activity and has a good synergistic effect with the cinnamaldehyde; the cinnamaldehyde and the pogostone are suitable for being used after being combined; compared with the bacteriostasis activity after the cinnamaldehyde and the ageratum oil are combined, the bacteriostasis activity after the pogostone and the cinnamaldehyde are combined is remarkably improved, and the safety is good.

Description

Technical field

[0001] The invention relates to a traditional Chinese medicine composition, which can be used to prepare medicines against Candida infection. Background technique

[0002] With the widespread use of broad-spectrum antibiotics, corticosteroids, and immunosuppressive agents, deep fungal infections have become more and more common in various clinical disciplines, and have become complications of severely endangered high-risk patients, including blood diseases, ICUs, tumors, and lung fungal infection , AIDS and other important factors of death. The first pathogenic bacteria is Candida, with a fatality rate of 30-60%. Among them, the mortality rate of Candida krusei infection is as high as 100%. At present, the treatment of deep fungal infections caused by Candida is mostly chemical synthesis, such as fluconazole, itraconazole, caspofungin, voriconazole, etc., although they have different degrees of antibacterial effects, they are expensive and have serious side effec...

Examples

Embodiment 1

[0041] Cinnamaldehyde: 1.25g (50 parts by weight),

[0042] Patchouli ketone: 1.25g (50 parts by weight).

Embodiment 2

[0044] Cinnamaldehyde: 1.25g (50 parts by weight),

[0045] Patchouli ketone: 1.25g (50 parts by weight),

[0046] Tween 80: 0.05g (2 parts by weight).

Embodiment 3

[0048] Cinnamaldehyde: 4.0g (80 parts by weight),

[0049] Patchouli ketone: 2.0g (40 parts by weight),

[0050] Tween 80: 0.05g (1 part by weight).

Technical field

[0001] The invention relates to a traditional Chinese medicine composition, which can be used to prepare medicines against Candida infection. Background technique

[0002] With the widespread use of broad-spectrum antibiotics, corticosteroids, and immunosuppressive agents, deep fungal infections have become more and more common in various clinical disciplines, and have become complications of severely endangered high-risk patients, including blood diseases, ICUs, tumors, and lung fungal infection , AIDS and other important factors of death. The first pathogenic bacteria is Candida, with a fatality rate of 30-60%. Among them, the mortality rate of Candida krusei infection is as high as 100%. At present, the treatment of deep fungal infections caused by Candida is mostly chemical synthesis, such as fluconazole, itraconazole, caspofungin, voriconazole, etc., although they have different degrees of antibacterial effects, they are expensive and have serious side effec...

Examples

Embodiment 1

[0041] Cinnamaldehyde: 1.25g (50 parts by weight),

[0042] Patchouli ketone: 1.25g (50 parts by weight).

Embodiment 2

[0044] Cinnamaldehyde: 1.25g (50 parts by weight),

[0045] Patchouli ketone: 1.25g (50 parts by weight),

[0046] Tween 80: 0.05g (2 parts by weight).

Embodiment 3

[0048] Cinnamaldehyde: 4.0g (80 parts by weight),

[0049] Patchouli ketone: 2.0g (40 parts by weight),

[0050] Tween 80: 0.05g (1 part by weight).

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