Sample reagent dispensing device, immunity analyzer and method thereof

Abstract

A sample reagent dispensing device, comprising a conveying unit (10), an accommodating unit (20), a first dispensing station (30) located on the periphery of the accommodating unit (20), a second dispensing station (201) located on the accommodating unit (20), a dispensing unit (40) and a control unit. An immunity analyzer, comprising the above-mentioned sample reagent dispensing device, a cleaning unit and an optical detection unit. In the present application, a first reaction component and a second reaction component are respectively dispensed in the first dispensing station (30) and the second dispensing station (201), thereby realizing the parallel operation of the dispensation of the first reaction component and other operation of the accommodating unit (20), and improving the test efficiency; when the second reaction component is dispensed, it is not necessary to convey a reaction vessel out of the accommodating unit (20), thereby simplifying the test steps and flow; the arrangement of the dispensing unit (40) thereof is no longer limited to the periphery of the accommodating unit (20), and the first dispensing station (30) and the second dispensing station (201) can be separately distributed, thereby avoiding the limitation and interference between dispensing units (40) in space.

Description

Technical field [0001] This application relates to the field of medical equipment, and in particular to a sample reagent dispensing device, an immune analyzer and a method thereof. Background technique [0002] Immune analyzers are often used in clinical laboratories to detect various analytical components of blood, urine or other body fluids. The immune analyzer needs to support immune response modes such as competition method, sandwich method, indirect method and capture method. Immunoassay methods mainly include radioimmunoassay, enzyme-linked immunoassay and luminescence immunoassay. Due to the advantages of environmental protection, high detection sensitivity, and wide detection range, luminescence immunoassay has become the main technical means of clinical immunoassay. Luminescence immunoassay is a new type of labeled immunoassay method for detecting trace antigens or antibodies established by combining luminescence analysis and immune response. It realizes the combinatio...

AI Technical Summary

Problems solved by technology

[0011] In the automatic analysis technology of inspection, blood cell analysis generally uses a puncture-type sample needle to dispense the sample, and then the sample is dispensed to a fixed reagent dispensing station using a fluid system to realize reagent dispensing. This automatic analysis device and method are limited to Analysis with few types of reagents, and its liquid circuit system is complicated, the cost of the instrument is high, and the reliability is low

For biochemical analyzers, reaction trays are generally used, and sample dispensing stations, reagent dispensing stations, stirring and mixing stations, and cleaning stations are arranged on the reaction trays. The injection station and the reagent dispensing station dispense samples and reagents to the reaction containers on the reaction tray. However, this dispensing device requires the reaction tray to move according to a specific cycle and regularity. When sample and reagent dispensing is performed on the reaction tray, the reaction The disk must be in a stopped state, thereby limiting the movement of the reaction disk, which has great limitations on the flexible testing process. In addition, the movement trajectory of the sample needle and / or reagent needle must pass through the reaction disk, which limits the The layout of the sample needle and / or reagent needle is increased, which increases the difficulty of implementation

[0012] In addition to using devices and methods similar to biochemical analysis, immunoassays also adopt the method of setting dispensing stations outside the incubation reaction area, that is, dispensing samples and reagents at the dispensing station, and then dispensing the samples and reagents. The reaction container is transferred to the incubation reaction area. In this way, the sample needle and reagent needle must be arranged around the dispensing station, and the dispensing time of the sample and reagent must be staggered, so it is only suitable for low-throughput (low-speed) analyzers. And when the sample and the reaction container of the first reagent dispensing are transferred to the incubation reaction area to complete the incubation for a period of time, when dispensing the second reagent, the reaction container needs to be transferred to the dispensing station, and after adding the second reagent Then transfer to the incubation reaction area, which increases the complexity of the transfer action and the implementation process

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