A device for stretching and growing nerve axons

Abstract

The invention discloses a nerve axon stretching grower which consists of a culturing and stretching control system and a mechanical device, wherein the culturing and stretching control system comprises a cell culture box, an upper computer, a controller and a stepping motor; the mechanical device comprises a coupler which is connected with the stepping motor, a ball screw linear sliding table, a stretching connecting block, a cell stretching grower, a device supporting rack and a chassis; the controller is connected with and drives the stepping motor to rotate so as to drive the ball screw linear sliding table at one end of the coupler to generate displacement, and the cell stretching grower is fixedly arranged on the device supporting rack and is used for indirectly stretching nerve axons by virtue of the stretching connecting block which is fixedly arranged on the linear sliding table. Different input commands can be set by virtue of the controller so as to regulate the growing direction and speed of the nerve axons. In addition, electrode contacts can be plated on a stretching film and a bottom film and can be connected with a multichannel neural signal recording and stimulating system for recording neural signals of the nerve axons and selectively stimulating different sites.

Description

technical field

[0001] The invention belongs to the field of biomedical experimental equipment, and more specifically relates to a nerve axon pulling and growing device. Background technique

[0002] According to the data released by the US National Spinal Cord Injury Statistics Center in 2011, there are currently about 265,000 spinal cord injury patients in the United States, and an average of about 12,000 new spinal cord injury patients are added each year. In China, about 60,000 new patients with spinal cord injury are added every year. The current clinical treatment of spinal cord injury mainly includes surgery, drug therapy and long-term exercise rehabilitation. However, the massive loss of neural tissue and the failure of regenerative function make current treatment options very limited. At this stage, clinically, autologous nerve transplantation is mainly used for nerve repair, which can not only fill the defect, but also provide an internal guide for the extension ...

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