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Preparation method of Yunkang capsules

A technology of capsules and Yunkang, which is applied in capsule delivery, medical preparations containing active ingredients, and pharmaceutical formulas, etc. It can solve the problems that it is difficult to guarantee the efficacy and cannot be directly made into capsule preparations, and achieve the effect of meeting consumer demand

Inactive Publication Date: 2015-01-07
上海海虹实业(集团)巢湖今辰药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because the preparation of traditional Yunkang syrup contains water, which will dissolve the liquid medicine of the capsule wall, it cannot be directly made into capsule preparations, and it is difficult to ensure that the new dosage form can achieve the original effect when changing the processing technology of the raw materials in Yunkang syrup. Efficacy of Yunkang Syrup

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment 1

[0019] The preparation method of the Yunkang Capsules provided in this specific implementation is made by the following raw materials in parts by mass: 150 parts of yam, 90 parts of Dipsacus, 120 parts of Radix Astragali, 90 parts of Angelica sinensis, 120 parts of dog spines, 90 parts of dodder, 60 parts of mulberry, 90 parts of Eucommia, 90 parts of psoralen, 90 parts of codonopsis, 120 parts of poria cocos, 90 parts of Atractylodes macrocephala, 30 parts of donkey-hide gelatin, 120 parts of rehmannia glutinosa, 90 parts of dogwood, 120 parts of medlar, 60 parts of black plum 90 parts of white peony root, 60 parts of amomum, 60 parts of Yizhi, 90 parts of ramie root, 60 parts of scutellaria baicalensis, 10 parts of mugwort leaves;

[0020] Step 1. Soak the above raw materials except donkey-hide gelatin in warm water at 50-60°C for 4 hours, and the amount of water is 5 times the total mass of the raw materials used for soaking, filter after soaking, and use the filtrate for la...

Embodiment 1

[0027] The preparation method of the Yunkang Capsules provided in this specific implementation is made by the following raw materials in parts by mass: 150 parts of yam, 90 parts of Dipsacus, 120 parts of Radix Astragali, 90 parts of Angelica sinensis, 120 parts of dog spines, 90 parts of dodder, 60 parts of mulberry, 90 parts of Eucommia, 90 parts of psoralen, 90 parts of codonopsis, 120 parts of poria cocos, 90 parts of Atractylodes macrocephala, 30 parts of donkey-hide gelatin, 120 parts of rehmannia glutinosa, 90 parts of dogwood, 120 parts of medlar, 60 parts of black plum 90 parts of white peony root, 60 parts of amomum, 60 parts of Yizhi, 90 parts of ramie root, 60 parts of scutellaria baicalensis, 10 parts of mugwort leaves;

[0028] Step 1. Soak the above raw materials except donkey-hide gelatin in warm water at 50-60°C for 4 hours, and the amount of water is 5 times the total mass of the raw materials used for soaking, filter after soaking, and use the filtrate for la...

Embodiment 2

[0034] The preparation method of the Yunkang Capsules provided in this specific implementation is made by the following raw materials in parts by mass: 150 parts of yam, 90 parts of Dipsacus, 120 parts of Radix Astragali, 90 parts of Angelica sinensis, 120 parts of dog spines, 90 parts of dodder, 60 parts of mulberry, 90 parts of Eucommia, 90 parts of psoralen, 90 parts of codonopsis, 120 parts of poria cocos, 90 parts of Atractylodes macrocephala, 30 parts of donkey-hide gelatin, 120 parts of rehmannia glutinosa, 90 parts of dogwood, 120 parts of medlar, 60 parts of black plum 90 parts of white peony root, 60 parts of amomum, 60 parts of Yizhi, 90 parts of ramie root, 60 parts of scutellaria baicalensis, 10 parts of mugwort leaves;

[0035] Step 1. Add water to decoct the above-mentioned raw materials except donkey-hide gelatin and filter 3 times. The amount of water added each time is 4 times the quality of the dregs used for decocting. The decocting time for the 3 times is 2...

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PUM

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Abstract

The invention discloses a preparation method of Yunkang capsules. 22 traditional Chinese medicinal materials such as Chinese yams, himalayan teasel roots and milkvetch roots are processed as follows: Step 1, the bulk drugs are soaked with warm water at the temperature of 50-60 DEG C and then filtered, and a filtrate is reserved for use; Step 2, dregs filtered out in Step 1 are decocted with water and then filtered, and a filtrate is reserved for use; Step 3, the filtrate obtained in Step1 and the filtrate obtained in Step 2 are merged, a bulk drug, namely, ass hide glue, is added, and the mixture is concentrated to be prepared into thick paste; Step 4, alcohol precipitation is performed on the thick paste obtained in Step 3, a supernate is taken and concentrated to be prepared into refined thick paste; Step 5, the refined thick paste obtained in Step 4 is depressurized and dried to be prepared into dry paste powder; Step 6, magnesium stearate and starch slurry are added into the dry paste powder obtained in Step 5, the magnesium stearate, the starch slurry and the dry paste powder are mixed evenly, and the capsules are obtained through filling. The preparation method of the Yunkang capsules can ensure that new dosage forms can realize effects of original Yunkang syrup and can satisfy actual production requirements and consumption needs.

Description

technical field [0001] The invention relates to a method for preparing Yunkang capsules, belonging to the technical field of pharmaceutical product production. Background technique [0002] Yunkang Syrup is a well-known drug for invigorating the spleen, strengthening the kidney, nourishing blood and anti-abortion. It is mainly used to treat threatened abortion and habitual abortion of kidney deficiency type and Qi and blood deficiency type. As we all know, the syrup preparations of traditional Chinese medicine are easily contaminated by microorganisms during the preparation and storage process due to the sugar and other nutrients, resulting in mildew and deterioration of the syrup; Appropriate preservatives are used to prevent or delay the proliferation of microorganisms, so that the quality of syrup meets hygienic requirements. It can be seen that the preparation form of Yunkang Syrup results in a short shelf life and a high risk of mildew and deterioration. [0003] Caps...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61K9/48A61P15/06A61K35/36
CPCA61K36/8945A61K9/4866A61K35/36A61K36/076A61K36/11A61K36/185A61K36/232A61K36/282A61K36/284A61K36/344A61K36/39A61K36/40A61K36/46A61K36/481A61K36/487A61K36/539A61K36/65A61K36/71A61K36/736A61K36/804A61K36/815A61K36/9062A61K36/9064A61K2236/331A61K2236/39A61K2236/53A61K2300/00
Inventor 梁延波刘声伟邱振海
Owner 上海海虹实业(集团)巢湖今辰药业有限公司
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