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An adjuvant drug for postoperative chemotherapy of non-small cell lung cancer

A non-small cell lung cancer and drug technology, which is applied in the direction of drug combination, antineoplastic drugs, and pharmaceutical formulations, can solve problems such as conflicts, shortages, and effects on curative effects, and achieve the goal of promoting tumor growth, reducing tumor weight, and increasing tumor inhibition rate Effect

Inactive Publication Date: 2018-04-27
刘新刚 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in prescriptions, the two drugs are used together, and their effects conflict, affecting the curative effect.
[0005] Therefore, there is still a lack of a traditional Chinese medicine or formula that does not simply start from the perspective of "killing" or "strengthening", and is used in conjunction with radiotherapy and chemotherapy for synergistic use.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Example 1, the weight ratio of raw materials: 20g of Rhizoma japonica, 20g of Ginger Flower, 6g of Ye Chuxiao, 9g of Pinellia Qu, 6g of Polygonum multiflorum, 10g of Red Trifolium, 10g of Senecio, 3g of Chinese Japonica, 10g of Shichangpu, osmanthus sticks 2g.

[0018] The preparation method of Example 1 is: mix and decoct the seeds of wild pluck, wood ginger flower, night blow flute, pinellia song (decoction), fleece-flower root, red clover, Senecio, acacia, calamus and cassia twig, Take the filtrate after 30 minutes, add water to the dregs of the medicine and continue to decoct for 20 minutes, then take the filtrate, combine the two filtrates, divide into two parts and take it in the morning and evening.

Embodiment 2

[0019] Example 2, the weight ratio of raw materials: 10 parts of Rhizoma chinensis, 10 parts of Mujianghua, 3 parts of Ye Chuan Xiao, 6 parts of Pinellia Qu, 3 parts of Polygonum multiflorum, 6 parts of red clover, 6 parts of Senecio, and acacia 1 part, 6 parts of Shichangpu, 1 part of Guizhi.

Embodiment 3

[0020] Example 3, the weight ratio of raw materials: 20 parts of Rhizoma chinensis, 20 parts of Mujianghua, 6 parts of Ye Chuan Xiao, 9 parts of Pinellia Qu, 6 parts of Polygonum multiflorum, 10 parts of red clover, 10 parts of Senecio, acacia 3 parts, Shichangpu 10 parts, Guizhi 2 parts.

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PUM

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Abstract

The invention discloses an assisted drug for postoperative chemo-treatment of non-small cell lung cancer and solves the problem of treatment of postoperative chemo-treatment. The assisted drug is characterized by being prepared from the following drug substances in weight ratio: elsholtzia rugulosa, leaves of tomentosecalyx elsholtzia, Leycesteria formosa Wall, fermented pinellia, fleece-flower root, red clover, groundsel, honey locust, grassleaf sweelflag rhizome and cassia twig. Clinical trials prove that the assisted drug is good in effect and relatively high in security in chemo-treatment and synergism, and is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to an auxiliary drug for postoperative chemotherapy of non-small cell lung cancer. Background technique [0002] The incidence of malignant tumors has been increasing in recent years. Chemotherapy, surgery, and radiotherapy are the main means of cancer treatment. Maximum tolerated dose chemotherapy (maximum tolerated dose, MTD) is the main form of traditional chemotherapy. Due to its heavy side effects, each cycle of chemotherapy requires an interval of 2 to 3 weeks to facilitate the recovery of body tissue and organ functions, which is prone to tumor resistance. medicine. At present, there are many theories such as the tumor stem cell hypothesis, which can explain that tumor cells are not sensitive to radiotherapy and chemotherapy or develop drug resistance or resistance during treatment, resulting in tumor recurrence and metastasis. In order to "completely" kill tumo...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8888A61P35/00
CPCA61K9/4808A61K36/28A61K36/355A61K36/48A61K36/483A61K36/53A61K36/54A61K36/704A61K36/888A61K36/8888A61K2300/00
Inventor 刘新刚魏玉珍孙永福
Owner 刘新刚
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