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Chinese medicinal preparation for treating nonspecific cystitis and preparation method thereof

A traditional Chinese medicine preparation and non-specific technology, applied in the field of pharmacy, can solve problems such as poor effect and certain side effects, and achieve the effect of less side effects and definite curative effect

Inactive Publication Date: 2015-02-11
于晓红
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine mostly adopts antibacterial treatment, which is often ineffective and has certain side effects

Method used

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Examples

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Comparison scheme
Effect test

preparation example Construction

[0045] Wherein, when the dosage form of described Chinese medicine preparation is powder, its preparation method comprises the following steps:

[0046] In the first step, the heart leaf hubu, wrinkled leaves, round knot mountain leech and wild hops are mixed according to the stated ratio, and the alcohol concentration is 80% to 95% of ethanol relative to the mass of the obtained mixture. Dissolve, heat and reflux for 5 to 8 hours to extract, filter to obtain the first filtrate; dissolve the filter residue again with ethanol with an alcohol concentration of 80% to 90% relative to the mass of the obtained mixture, and heat to reflux for 3 to 5 Extract for 1 hour, filter to get the second filtrate; combine the first filtrate and the second filtrate, recover ethanol under reduced pressure and concentrate until the concentration of the drug solution is 0.4-0.9g crude drug / mL, and pass through a macroporous adsorption resin with a volume of 5L For column elution, first use 3 times ...

Embodiment 1

[0057] The powder prepared by embodiment 1 the present invention

[0058] Take 280g of heart leaf Hubu, 150g of wrinkled leaves, 220g of leeches, 280g of wild hops, 120g of bristles, 150g of fangji, 200g of big trees, 180g of lilac polygonum, 300g of black dragon silk, 200g of big hair, point glands 150g of Guoluhuang, 260g of Golden Kidney, 210g of Nine-section Wood, 300g of Dung Jidu and 200g of Typhoid Head;

[0059] Its preparation method comprises the following steps:

[0060] In the first step, the heart leaf hubu, wrinkled leaves, round knot mountain leech and wild hops are mixed according to the stated ratio, dissolved in ethanol with an alcohol concentration of 5 times relative to the obtained mixture mass, and heated to reflux for 6 Extract for 1 hour, filter to get the first filtrate; Dissolve the filter residue again with ethanol with an alcohol concentration of 85% relative to the mass of the obtained mixture 5 times, heat and reflux for 5 hours to extract, filte...

Embodiment 2

[0064] The capsule prepared by embodiment 2 the present invention

[0065] Take 260g of heart leaves Hubu, 180g of wrinkled leaves, 200g of leeches, 300g of wild hops, 150g of bristles, 150g of fangji, 180g of big trees, 200g of cloves, 280g of black dragon silk, 180g of big hair, point glands 200g Guoluhuang, 300g Golden Kidney, 200g Mosaic Nine-section Wood, 280g Dung Jidu and 180g Typhoid Head;

[0066] Its preparation method comprises the following steps:

[0067]In the first step, mix heart leaf hubu, wrinkled leaves, round knot mountain leech and wild hops according to the stated ratio, add water 5 times relative to the mixture to extract the volatile oil, and clathrate the obtained volatile oil with β-cyclodextrin , the ratio of volatile oil to β-cyclodextrin is 1:5, stirring for 180 minutes at a temperature of 60°C to obtain a volatile oil clathrate, and set aside; in addition, the water extract is concentrated to a clear paste with a relative density of 1.28 at 75°C;...

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PUM

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Abstract

The invention discloses a Chinese medicinal preparation for treating nonspecific cystitis and a preparation method thereof. Various raw herbal materials in the Chinese medicinal preparation comprise Humulus lupulus L. var. cordifolius Maxim., obovate ainsliaea, beggarweed, cordateleaf european hop flower, Adiantum davidii Franch, Aristolochia fangchi, Cleidion brevipetiolatum, Ludwigia prostrata, Adiantum philippense L., wild beans, Lysimachia hemsleyana, Chrysosplenium sinicum, Psychotria siamica, long stephania herb and rabdosia tenuifolia hara. The Chinese medicinal preparation provided by the invention has the beneficial effects of definite curative effect on nonspecific cystitis and low side effect.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine preparation for treating non-specific cystitis and a preparation method thereof. Background technique [0002] Cystitis is an inflammation of the bladder, mainly caused by specific and non-specific bacterial infections, and there are other special types of cystitis. Specific infection refers to bladder tuberculosis. Nonspecific cystitis is caused by Escherichia coli, vice Escherichia coli, Proteus, Pseudomonas aeruginosa, Streptococcus faecalis and Staphylococcus aureus. Its clinical manifestations are acute and chronic. The former has a sudden onset, burning sensation when urinating, and pain in the urethral area. Sometimes there is urgency and severe frequency. Common in women. Terminal hematuria is common, and in severe cases, gross hematuria and blood clots may be discharged. The symptoms of chronic cystitis are similar to those of acute ...

Claims

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Application Information

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IPC IPC(8): A61K36/74A61P13/10
CPCA61K9/14A61K9/4858A61K36/11A61K36/185A61K36/264A61K36/28A61K36/47A61K36/48A61K36/53A61K36/59A61K36/60A61K36/74A61K2300/00Y02A50/30
Inventor 于晓红
Owner 于晓红
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