Circovirus egg yolk antibody oral liquid and preparation method thereof
A technology of egg yolk antibody and oral liquid, which is applied in the direction of antibodies, pharmaceutical formulas, antiviral agents, etc., can solve the problems of inconvenient use of egg yolk antibody for porcine circular disease, improve immunity and stress ability, and have high bioavailability , biological activity is not affected by the effect
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Embodiment 1
[0017] A formula of porcine circovirus yolk antibody oral solution includes the following raw materials: 95 L of whole egg aqueous solution containing yolk antibody, 0.2 L of caprylic acid, 0.3 L of formaldehyde, 0.02 L of thimerosal, and 1000 units / ml of penicillin and streptomycin in the oral solution.
[0018] Its preparation method comprises the following steps:
[0019] 1) Use the commercially available inactivated porcine circovirus vaccine for booster immunization. The dose of vaccine per chicken is 2ml each time, and the immunization procedure is carried out three times at intervals of 10 days. When the antibody titer reaches 1:256, start collecting High free eggs.
[0020] 2) Sort the collected high-free eggs, sterilize with 0.2% bromogeramine, and set aside.
[0021] 3) Acidification treatment by water dilution method: Beat 2) Bugao egg-free whole eggs into the pasteurized tank for full emulsification. The emulsification time is 7 minutes, and then add the emulsifie...
Embodiment 2
[0040] A formula for porcine circovirus yolk antibody oral solution includes the following raw materials: 105 L of whole egg aqueous solution containing yolk antibody, 0.2 L of octanoic acid, 0.2 L of formaldehyde, 0.01 L of thimerosal, and 800 units / ml of penicillin and streptomycin in the oral solution.
[0041] Its preparation method comprises the following steps:
[0042] 1) Use the commercially available inactivated porcine circovirus vaccine for booster immunization. The dose of vaccine per chicken is 2ml each time, and the immunization procedure is carried out three times at intervals of 10 days. When the antibody titer reaches 1:128, start collecting High free eggs.
[0043] 2) Sort the collected high-free eggs, sterilize with 0.1% bromogeramine, and set aside.
[0044] 3) Acidification treatment by water dilution method: Beat 2) Bugao egg-free whole eggs into the pasteurized tank for full emulsification, emulsification time is 10 minutes, and then add the emulsified ...
Embodiment 3
[0063] A formula for porcine circovirus yolk antibody oral solution includes the following raw materials: 100 L of whole egg aqueous solution containing yolk antibody, 0.3 L of octanoic acid, 0.3 L of formaldehyde, 0.02 L of thimerosal, and 1000 units / ml of penicillin and streptomycin in the oral solution.
[0064] Its preparation method comprises the following steps:
[0065] 1) Use the commercially available inactivated porcine circovirus vaccine for booster immunization. The dose of vaccine per chicken is 2ml each time, and the immunization procedure is carried out three times at intervals of 10 days. When the antibody titer reaches 1:256, start collecting High free eggs.
[0066] 2) Sort the collected high-free eggs, sterilize with 0.2% bromogeramine, and set aside.
[0067] 3) Acidification treatment by water dilution method: Beat 2) Bugao egg-free whole eggs into the pasteurized tank for full emulsification, emulsification time is 8 minutes, and then add the emulsified ...
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