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Supercritical extraction method of Periplaneta americana oil and preparation of defatted Periplaneta americana

A Periplaneta americana, supercritical technology, applied in the direction of fat oil/fat production, fat production, digestive system, etc., can solve problems such as few researches, achieve the effect of reducing side effects, high degreasing rate, and convenient operation

Active Publication Date: 2018-05-01
SICHUAN GOODDOCTOR PANXI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are few studies on the pretreatment of Periplaneta americana medicinal materials

Method used

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  • Supercritical extraction method of Periplaneta americana oil and preparation of defatted Periplaneta americana
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  • Supercritical extraction method of Periplaneta americana oil and preparation of defatted Periplaneta americana

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Example 1 Extraction of Periplaneta americana Oil

[0020] Periplaneta americana medical material is crushed into coarse powder, weighs 250g coarse powder, puts in supercritical CO 2 In the extraction device, at a pressure of 30MPa and a temperature of 40°C, CO 2 Extract for 2 hours at a flow rate of 20 L / h, and collect the oil of Periplaneta americana.

Embodiment 2

[0021] Example 2 Extraction of Periplaneta americana Oil

[0022] Periplaneta americana medical material is crushed into coarse powder, weighs 250g coarse powder, puts in supercritical CO 2 In the extraction device, at a pressure of 20MPa and a temperature of 30°C, CO 2 Extract for 1 hour at a flow rate of 10 L / h, and collect the oil of Periplaneta americana.

Embodiment 3

[0023] Example 3 Extraction of Periplaneta americana oil

[0024] Periplaneta americana medical material is crushed into coarse powder, weighs 250g coarse powder, puts in supercritical CO 2 In the extraction device, at a pressure of 40MPa and a temperature of 50°C, CO 2 Extract for 3 hours at a flow rate of 30L / h, and collect the oil of Periplaneta americana.

[0025] Taking the oil yield of Periplaneta americana as the evaluation index, the pressure, temperature, CO 2 The traffic and extraction time were investigated, and the results are as follows:

[0026]

[0027] According to the above table, it can be known that the present invention uses the supercritical extraction method to effectively extract the oil of Periplaneta americana, and wherein the extraction rate is the best with the operating conditions of Example 2.

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Abstract

The invention provides a preparation method of degreased periplaneta americana. The preparation method comprises the following steps: grinding the medicinal material periplaneta americana, putting the ground periplaneta americana in a supercritical CO2 extraction device to be extracted, respectively collecting grease and dregs, and taking the dregs, namely the degreased periplaneta americana. Studies show that the prepared degreased periplaneta americana medicinal material has the effect of obviously reducing the side effects during gastric ulcer treatment, and provides a new choice for clinical medication; meanwhile, the method is high in degreasing rate, is convenient and fast to operate and is suitable for industrial production.

Description

technical field [0001] The invention relates to a method for extracting fat from Periplaneta americana and preparation of defatted Periplaneta americana. Background technique [0002] Periplaneta Americana (Periplaneta Americana) belongs to Insecta, Blattata, Blatidae, "cockroach" is its common name, first seen in "Compendium of Materia Medica Supplements", also known as Shijiang, slipworm, has survived on the earth for 3.5 It is one of the most vigorous, oldest, and most successful insect groups in the world. The main medicine of Periplaneta americana is lumps and accumulation, and it can benefit the blood vessels. External use can suppress sores, pull out toxins, eliminate decay, and promote muscle growth. Modern research shows that it also has good antibacterial effects. [0003] The main component of Kangfuxin liquid is the ethanol extract of the dried worm body of Periplaneta americana, which can benefit blood vessels, nourish yin and strengthen muscles. Modern medicin...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K35/64C11B1/10A61P1/04
CPCA61K35/63C11B1/104
Inventor 苏柘僮熊永爱邹俊波
Owner SICHUAN GOODDOCTOR PANXI PHARMA