Device and method for positioning and sample feeding of low-field magnetism resonance system

Abstract

The invention discloses a device for positioning and sample feeding of a low-field magnetism resonance system, and also discloses a method for the positioning and sample feeding of the low-field magnetism resonance system. The device for the positioning and sample feeding comprises an air compressor and a vacuum pump, wherein the air compressor and the vacuum pump are connected with a noncircular sample feeding guide pipe through a pipeline; a positioner and a guide pipe lower cover are arranged on the noncircular sample feeding guide pipe, and are arranged in a net cover and a shielding box; a computer is used for controlling a noncircular positioning slide block loaded with a nuclear magnetic sample pipe to do reciprocating conveying in a fixed-direction and non-rotating way between a permanent magnet and the positioner through two electromagnetic valves, so as to guarantee that the nuclear magnetic product can be stably and quickly positioned into a detection area of the net cover and the center of the shielding box; by using the noncircular sample feeding guide pipe which is made of a PEEK (poly ether ether ketone) material and the nuclear magnetic sample pipe which is coated with a high temperature-resistant and heat-insulation material, the constant temperature of a nuclear magnetic sample is guaranteed. The device has the advantages that the structure is simple, the operation is convenient, the positioning, sample feeding and effective heat insulation are realized, and the device is suitable for the detection NMR (nuclear magnetic resonance) and MRI (magnetic resonance imaging) study based on an atom magnetic meter method.

Description

technical field [0001] The invention relates to the field of pneumatic and vacuum method transmission, vehicle monitoring and management of sample heat preservation parking lot, in particular to a positioning sampling device for a low-field magnetic resonance system, and also relates to a positioning sampling device for a low-field magnetic resonance system The method is suitable for the positioning sampling of magnetic resonance imaging (MRI) based on the atomic magnetometer method, and can also be extended to the detection of NMR samples such as flowing gas and liquid. Background technique [0002] The pneumatic method is a common traditional method for transporting NMR samples in NMR spectrometers. In traditional high-field NMR spectrometers, the polarization and signal detection of nuclear magnetic samples are usually completed in the same area in the superconducting magnet, and the nuclear magnetic samples are pneumatically transported to the detection area of ​​the NMR...

AI Technical Summary

Problems solved by technology

However, (1) devices based on these two methods require a long transmission pipeline to connect the prepolarization area and the detection area

Therefore, a large amount of liquid NMR samples are required to fill the transmission pipeline in the experiment, and the amount of liquid NMR samples used is large, which is not suitable for a small amount of liquid NMR samples; MRI research; (3) After testing a flow sample, it is not convenient to replace the sample and clean the transmission pipeline

[0008] 3) Valerio Biancalan et al. described in the article "A fast pneumatic sample-shuttle with attenuated shocks" (Review of Scientific Instrument, 85, 036104 (2014)), using special opening changes on the injection tube and injection slide Internal airflow to reduce the vibration of the NMR sample tube during the transfer and injection process, however, it is not suitable for high temperature working environment, nor can it be extended to MRI research based on the atomic magnetometer method

Therefore, when biological NMR samples are used, it is difficult to ensure that the NMR samples remain in the same state after each transfer to the detection area by using the existing circular tube (cavity, airway, etc.) sampling method or technology, and it is also difficult to ensure that It is not affected by the high temperature working atomic vapor bubble

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