Antibacterial and anti-inflammatory Chinese herbal compound gel and preparation method thereof

A technology of compound gel and traditional Chinese medicine, which is applied in the direction of antibacterial drugs, antifungal agents, and pharmaceutical formulas, and can solve problems affecting curative effect, bacterial drug resistance, and human injury, etc., and achieves non-toxic side effects, obvious effects, and obvious synergy The effect of action

Inactive Publication Date: 2015-09-23
ZHUHAI COLLEGE OF JILIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Conventional drugs for the treatment of infection are mainly chemical drugs, long-term use is likely to cause bacterial drug resistance, affect the curative effect, and even cause harm to the human body

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] 1) Weigh gallbladder 25g, saponin thorn 20g, cnidium 15g, scutellaria baicalensis 30g, bitter bean 15g, bitter clove 15g, poplar leaf root 10g, tea tree essential oil 2g, liquidambar essential oil 1.2g, borneol 5g, 55% Ethanol 8g, carbomer 1.5g, triethanolamine 15g, methylparaben 0.8g;

[0026] 2) Put the Chinese herbal medicine into the reflux device, add water 8 times the weight of the traditional Chinese medicine into the container, heat and reflux for extraction for 1.5 hours, filter, add water 8 times the total weight of the Chinese medicine to the medicinal residue, heat and reflux for extraction for 1.5 hours, and combine the two Gained filtrate, the filtrate is concentrated to the original drug concentration of 0.5g / ml, through 4000rpm, centrifugal 10min, get supernatant, set aside.

[0027] 3) Disperse 1.5g of carbomer evenly in pure water and soak, and wait until fully dissolved to obtain a phase A solution.

[0028] 4) Dissolve 5g of borneol in 8g of 55% eth...

Embodiment 2

[0032] 1) Weigh gallbladder 35g, saponins 10g, cnidium 25g, scutellaria baicalensis 20g, bitter beans 25g, bitter clove 10g, poplar root 25g, tea tree oil 1.2g, liquidambar essential oil 1g, borneol 8g, 55% 10g of ethanol, 1.2g of carbomer, 12g of triethanolamine, and 1g of platinum methyl ester;

[0033] 2) Put the Chinese medicinal materials into the reflux device, add water 15 times the weight of the traditional Chinese medicine into the container, heat and reflux for extraction for 2.5 hours, filter, add water 15 times the total weight of the traditional Chinese medicine to the medicinal residue, heat and reflux for 2.5 hours, and combine the two The resulting filtrate was concentrated to the concentration of the original drug of 0.8g / ml, and centrifuged at 4000rpm for 10min, and the supernatant was taken for subsequent use.

[0034] 3) Disperse 1.2g of carbomer evenly in pure water and soak it, and wait until it is fully dissolved to obtain a phase A solution.

[0035] 4...

Embodiment 3

[0038] 1) Weigh gallbladder 15g, saponin thorn 35g, cnidium 20g, scutellaria baicalensis 15g, bitter bean 15g, bitter clove 20g, poplar leaf root 12g, tea tree essential oil 1g, sweetgum leaf essential oil 0.5g, borneol 10g, 55% Ethanol 6g, carbomer 1g, triethanolamine 10g, methylparaben 0.5g;

[0039] 2) Put the Chinese medicinal materials into the reflux device, add water 10 times the weight of the traditional Chinese medicine into the container, heat and reflux for extraction for 1 hour, filter, add water 10 times the total weight of the Chinese medicine for the dregs, heat and reflux for extraction for 1 hour, and combine the two results Filtrate, the filtrate is concentrated to the original drug concentration of 0.6g / ml, through 4000rpm, centrifugal 10min, take supernatant, set aside.

[0040] 3) Evenly disperse 1g of carbomer in pure water and soak it, and wait until it is fully dissolved to obtain a phase A solution.

[0041]4) Dissolve 10g of borneol in 6g of 55% etha...

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PUM

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Abstract

The invention discloses antibacterial and anti-inflammatory Chinese herbal compound gel and a preparation method thereof. The antibacterial and anti-inflammatory Chinese herbal compound gel is prepared from Chinese herbals and auxiliary materials applicable to external preparations; the Chinese herbals comprise Chinese gall gallnut, spina gleditsiae, fructus cnidii, scutellaria baicalensis, tea tree oil, menthol, borneol and the like. The antibacterial and anti-inflammatory Chinese herbal compound gel contains various antibacterial and anti-inflammatory components, and through the synergistic effect of all the raw materials, the antibacterial and anti-inflammatory effects are good, the antibacterial and anti-inflammatory Chinese herbal compound gel does not have irritation to skin, hypersensitivity and toxic or side effect.

Description

technical field [0001] The invention provides an antibacterial and anti-inflammatory traditional Chinese medicine compound gel and a preparation method thereof, which can be used in different forms or purposes such as a medicine for treatment or a disinfectant for auxiliary treatment, sanitary products, etc., and relates to the technical field of external skin preparations. Background technique [0002] Due to the wide application and even abuse of antibiotics, the emergence of bacterial resistance has been accelerated, and the situation of anti-infection treatment is becoming more and more severe. Conventional drugs for the treatment of infection are mainly chemical drugs, long-term use is likely to cause bacterial drug resistance, affect the curative effect, and even cause harm to the human body. The present invention selects medicinal materials with a long history of folk and clinical application in my country on the basis of literature review, and prepares a compound tra...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/74A61K36/70A61K9/06A61P17/00A61P17/04A61P31/04A61P31/10A61P15/00A61K35/64
Inventor 江连海侯绮兰滕利荣卢晓娥吴丽艳金元宝王雪
Owner ZHUHAI COLLEGE OF JILIN UNIV
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