Chitosan compound with function of enhancing immunity, preparation method thereof, and capsules containing chitosan compound
A technology for enhancing immunity and chitosan, which is applied in the directions of non-active ingredients medical preparations, medical preparations containing active ingredients, and capsule delivery, etc. It can solve problems such as single formula and function, and no adjustment to consider compatibility. , to achieve the effect of enhancing immunity, improving self-immunity, and enhancing absorption capacity
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Embodiment 1
[0034] A kind of preparation method of chitosan, concrete steps are as follows:
[0035] (1) Add chitin to 50% NaOH solution at a ratio of 1:15, and heat at 80°C for 20 minutes under the condition of microwave power 650W; after cooling to room temperature, filter, rinse repeatedly with pure water until neutral, and dry Dry; Obtain chitosan crude product; The chitosan crude product that obtains repeats above-mentioned steps 2 times;
[0036] (2) the crude product of chitosan prepared by step (1) is dissolved in 5% acetic acid, and the insoluble matter is removed by filtration, and then the NaOH solution with a concentration of 10% is used to separate out colloidal matter, filtered, washed to neutrality, and dried. Get chitosan refined products.
Embodiment 2
[0038] A chitosan compound with the function of enhancing immunity is composed of the following components according to the weight ratio:
[0039] Chitosan: Lycium barbarum extract: Ganoderma lucidum extract: Ginkgo biloba extract = 45:33:15:7.
[0040] The specific steps of the preparation method are as follows:
[0041] (1) Under agitation, 50 g of chitosan was dissolved in 20 L of 1% (v / v) acetic acid solution; then, the chitosan solution was diluted with distilled water so that its final concentration was 2 mg / ml; Sodium oxide solution regulates the pH value of chitosan solution to be 6;
[0042] (2) Slowly add wolfberry fruit extract, ganoderma lucidum extract and ginkgo biloba extract to chitosan solution in sequence, ultrasonic power is 450W, working time is 20s, intermittent time is 15s, working 90 times, and embedding suspension is obtained liquid;
[0043] (3) Using spray drying technology to obtain finished microspheres.
[0044] A capsule with the function of e...
Embodiment 3
[0046] A chitosan compound with the function of enhancing immunity is composed of the following components according to the weight ratio:
[0047] Chitosan: Lycium barbarum extract: Ganoderma lucidum extract: Ginkgo biloba extract = 50:32:11:7.
[0048] The specific steps of the preparation method are as follows:
[0049] (1) Under stirring condition, 80g chitosan is dissolved in 32L concentration and is 1% (v / v) acetic acid solution; Then, dilute chitosan solution with distilled water, make its final concentration be 2mg / ml; Sodium oxide solution regulates the pH value of chitosan solution to be 6;
[0050] (2) Slowly add wolfberry fruit extract, ganoderma lucidum extract and ginkgo biloba extract to chitosan solution in sequence, ultrasonic power is 450W, working time is 20s, intermittent time is 15s, working 90 times, and embedding suspension is obtained liquid;
[0051] (3) Using spray drying technology to obtain finished microspheres.
[0052] A capsule with the funct...
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